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  • Cited by 33
Publisher:
Cambridge University Press
Online publication date:
August 2009
Print publication year:
2004
Online ISBN:
9780511546358

Book description

Recent developments have extended our knowledge of the basic functions of nerves: notably, the demonstration of the mechanism within nerve fibers which transports a wide range of essential materials. In order to understand how this discovery occurred, it is necessary to examine its history. The story begins in ancient Greece when nerves were conceived of as channels through which animal spirits carried sensory impressions to the brain. As science developed, the discoveries of various physical and chemical agents supplanted the agency of animal spirits until the molecular machinery of transport was recognized. In this fascinating and complete history, Sidney Ochs begins with a chronological look at this path of discovery, followed in the second half by a thematic approach wherein the author describes the electrical nature of the nerve impulse, fiber form and its changes in degeneration and regeneration, reflexes, learning, memory and other higher functions in which transport participates.

Reviews

‘Sidney Ochs provides a richly referenced background to the evolution of our knowledge of the nature of normal conduction in the PNS and muscle. … he does provide a detailed account of the history and background of his own important work on the nature and function of transport mechanisms in nerve. … the book is an enjoyable and instructive read.‘

Source: Brain

‘This is an interesting book about the historical perspectives of nerve function …‘.

Source: Neurological Research

'It would be difficult to identify any book in recent years that could provide as much excitement and profound insight into this field in the context of its broad history… it would be difficult to match the informed succinct style of this remarkable pioneer who has bought us his wonderfully readable reflections on the origins of those questions that continue to attract and to inspire increasing numbers of talented individuals to the benches of neuroscience research.'

Source: Journal of the History of the Neuroscienes

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