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Chapter 13 - Fetal Thrombocytopenia (Content last reviewed: 15th March 2020)

from Section 3 - Late Prenatal – Fetal Problems

Published online by Cambridge University Press:  15 November 2017

David James
Affiliation:
University of Nottingham
Philip Steer
Affiliation:
Imperial College London
Carl Weiner
Affiliation:
University of Kansas
Bernard Gonik
Affiliation:
Wayne State University, Detroit
Stephen Robson
Affiliation:
University of Newcastle
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Summary

During normal fetal life, the platelet count progressively increases, reaching a level of approximately 150 × 109/L by the end of the first trimester. Thus, healthy fetuses and neonates have platelet counts within the normal range for adults (150–450 × 109/L). Therefore, fetal and neonatal thrombocytopenia is defined as a platelet count < 150 × 109/L regardless of gestational age. For severe thrombocytopenia with a risk of bleeding problems, a cutoff of 30–50 × 109/L is commonly used. Thus, many mild to moderately thrombocytopenic neonates show no symptoms, and the disease may go unnoticed.

Type
Chapter
Information
High-Risk Pregnancy
Management Options
, pp. 308 - 320
Publisher: Cambridge University Press
First published in: 2017

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