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  • Print publication year: 2019
  • Online publication date: July 2019

Chapter F - Chapter

from Drugs: An A–Z Guide


Fentanyl is 100 times as potent as morphine. Its onset of action is within 1–2 minutes after IV injection and a peak effect within 4–5 minutes. The duration of action after a single bolus is 20 minutes. The context-sensitive half-life following IV infusion is prolonged because of its large volume of distribution.