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Chapter 19 - Manipulation of Amniotic Fluid Volume: Homeostasis of Fluid Volumes in the Amniotic Cavity

from Manipulation of Fetal Amniotic Fluid Volume

Published online by Cambridge University Press:  21 October 2019

Mark D. Kilby
Affiliation:
University of Birmingham
Anthony Johnson
Affiliation:
University of Texas Medical School at Houston
Dick Oepkes
Affiliation:
Leids Universitair Medisch Centrum
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Summary

Human pregnancies contain large amounts of water in several compartments, including the fetal body, the placenta and membranes, and the amniotic fluid (AF). This water circulates within the conceptus and also between fetus and mother. Normal acquisition and circulation of water is critical to fetal health and development, and abnormal amounts of water, evidenced as insufficient (oligohydramnios) or excessive (polyhydramnios) amounts of AF, are associated with impaired fetal outcome, even in the absence of structural fetal abnormalities. This chapter will review the current understanding of water flow to the fetus and into and out of the amniotic cavity, and the evidence suggesting that the fetus may regulate AF volume.

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Chapter
Information
Fetal Therapy
Scientific Basis and Critical Appraisal of Clinical Benefits
, pp. 191 - 199
Publisher: Cambridge University Press
Print publication year: 2020

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