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Chapter 10 - Fetal and Neonatal Injury as a Consequence of Maternal Substance Abuse

from Section 2 - Pregnancy, Labor, and Delivery Complications Causing Brain Injury

Published online by Cambridge University Press:  13 December 2017

David K. Stevenson
Affiliation:
Stanford University, California
William E. Benitz
Affiliation:
Stanford University, California
Philip Sunshine
Affiliation:
Stanford University, California
Susan R. Hintz
Affiliation:
Stanford University, California
Maurice L. Druzin
Affiliation:
Stanford University, California
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References

Substance Abuse and Mental Health Services Administration. 2013 National Survey on Drug Use and Health: Summary of National Findings (NSDUH Series H-48, HHS Publication No. [SMA] 14–4863). Rockville, MD: Substance Abuse and Mental Health Services Administration, 2014.Google Scholar
Tan, CH, Denny, CH, Cheal, NE, et al. Alcohol use and binge drinking among women of childbearing age – United States, 2011–2013. MMWR 2015; 64(37): 1042–6.Google Scholar
Kelly, RH, Zatzick, DF, Anders, TF. The detection and treatment of psychiatric disorders and substance use among pregnant women cared for in obstetrics. Am J Psychiatry 2014; 158(2): 213–9.Google Scholar
Briggs, GG, Freeman, RK,Yaffe, SJ. Introduction. In Drugs in Pregnancy and Lactation, 9th edn. Philadelphia: Lippincott, Williams & Wilkins, 2011: xvxxii.Google Scholar
Kraemer, K. Placental transfer of drugs. Neonatal Netw 1997; 16: 65–7.Google Scholar
Mahone, PR, Scott, K, Sleggs, G, et al. Cocaine and metabolites in amniotic fluid may prolong fetal drug exposure. Am J Obstet Gynecol 1994; 171: 465–9.Google Scholar
Brent, RL. Environmental causes of human congenital malformations: the pediatrician’s role in dealing with these complex clinical problems caused by a multiplicity of environmental and genetic factors. Pediatrics 2004; 113: 957–68.Google Scholar
Konijnenberg, C. Methodological issues in assessing the impact of prenatal drug exposure. Substance Abuse Res Treat 2015; 9(S2): 3944.Google ScholarPubMed
Snodgrass, SR. Cocaine babies: a result of multiple teratogenic influences. J Child Neurol 1994; 9: 227–33.Google Scholar
Lemoine, P, Harousseau, H, Borteyru, JP, et al. Les enfants des parents alcoholiques: anomolies observees a propos de 127 cas (The children of alcoholic parents: anomalies observed in 127 cases). Quest Med 1968; 25: 476–82.Google Scholar
Jones, KL, Smith, DW, Ulleland, CN, Streissguth, AP. Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1973; 301(7815): 1267–71.Google Scholar
Stratton, K, Howe, C, Battaglia, F, eds. Institute of Medicine Fetal Alcohol Syndrome: Diagnosis, Epidemiology, Prevention, and Treatment. Washington: National Academy Press; 1996.Google Scholar
May, PA, Keaster, C, Bozeman, R, et al. Prevalence and characteristics of fetal alcohol syndrome and partial fetal alcohol syndrome in a Rocky Mountain region city. Drug Alcohol Depend 2015; 155: 118–27.Google Scholar
May, PA, Baete, A, Russo, J, et al. Prevalence and characteristics of fetal alcohol spectrum disorders. Pediatrics 2014; 134(5): 855–66.Google Scholar
May, PA, Blankenship, J, Marais, AS, et al. Approaching the prevalence of the full spectrum of fetal alcohol spectrum disorders in a South African population-based study. Alcohol Clin Exp Res. 2013; 37(5): 818–30.CrossRefGoogle Scholar
Centre for Addiction and Mental Health C. Fetal alcohol spectrum disorders: how widespread are they in Canada? Available at: www.camh.ca/en/hospital/about_camh/newsroom/news_releases_media_advisories_and_backgrounders/current_year/Pages/Fetal-Alcohol-Spectrum-Disorders-How-Widespread-Are-They-in-Canada.aspx (accessed March 29, 2016).Google Scholar
Abel, EL, Sokol, RJ. A revised conservative estimate of the incidence of FAS and its economic impact. Alcohol Clin Exp Res. 1991; 15(3): 514–24.Google Scholar
Harwood, H. Updating Estimates of the Economic Costs of Alcohol Abuse in the United States: Estimates, Updated Methods and Data. Report Prepared by the Lewin Group. Bethesda, MD:National Institute on Alcohol Abuse and Alcoholism, 2000.Google Scholar
Stade, BC, Ali, A, Bennett, D, et al. The burden of prenatal exposure to alcohol: revised measurement of cost. J Popul Ther Clin Pharmacol 2009; 16: e91102.Google ScholarPubMed
Williams, JF, Smith, VC; Committee on Substance Abuse. Fetal alcohol spectrum disorders. Pediatrics 2015; 136(5): e1395–406.CrossRefGoogle ScholarPubMed
Hoyme, HE, May, PA, Kalberg, WO, et al. A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. Pediatrics 2005; 115: 3947.Google Scholar
Astley, SJ, Clarren, SK. Diagnosing the full spectrum of fetal alcohol-exposed individuals: introducing the 4-digit diagnostic code. Alcohol Alcohol 2000; 35: 400–10.Google Scholar
World Health Organization. The ICD-10 Classification of Mental and Behavioral Disorders: Clinical Descriptions and Diagnostic Guidelines. Geneva: WHO, 1992.Google Scholar
American Psychiatric Association. A Diagnostic and Statistical Manual of Mental Disorders, 5th edn. Arlington, VA: American Psychiatric Publishing, 2013: 798801.Google Scholar
Centers for Disease Control and Prevention. Fetal Alcohol Spectrum Disorders: Guidelines for Referral and Diagnosis. Atlanta:CDC, 2004.Google Scholar
Chudley, AE, Conry, J, Cook, JL, et al. Fetal alcohol spectrum disorder: Canadian guidelines for diagnosis. CMAJ 2005; 172: S121.Google Scholar
Cook, JL, Green, CR, Lilley, CM, et al. Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan. CMAJ 2015; 188(3): 191–7.Google ScholarPubMed
Hoyme, HE, Kalberg, WO, Elliott, AJ, et al. Updated clinical guidelines for diagnosing fetal alcohol spectrum disorders. Pediatrics 2016; 138(2):pii: e20154256.Google Scholar
Swayze, VW, Johnson, VP, Hanson, JW, et al. Magnetic resonance imaging of brain anomalies in fetal alcohol syndrome. Pediatrics 1997; 99: 232–40.Google Scholar
Mattson, SN, Schoenfeld, AM, Riley, EP. Teratogenic effects of alcohol on brain and behavior. Alcohol Res Health 2001; 25(3): 185–91.Google Scholar
Spadoni, AD, McGee, CL, Fryer, SL, Riley, EP. Neuroimaging and fetal alcohol spectrum disorders. Neurosci Biobehav Rev 2007; 31(2): 239–45.Google Scholar
Jacobson, JL, Jacobson, SW, Sokol, RJ, et al. Effects of alcohol use, smoking and illicit drug use on fetal growth in black infants. J Pediatr 1994; 124: 757–64.CrossRefGoogle ScholarPubMed
Charness, ME, Safran, RM, Perides, G. Ethanol inhibits neural cell-cell adhesion. J Biol Chem 1994; 269: 9304–9.Google Scholar
DeJonge, MH, Zachman, RD. The effect of maternal ethanol ingestion on fetal rat heart vitamin A: a model for fetal alcohol syndrome. Pediatr Res 1995; 37: 418–23.Google Scholar
Naus, CCG, Bechberger, JF. Effect of prenatal ethanol exposure on postnatal neural gene expression in the rat. Dev Genet 1991; 12: 293–8.Google Scholar
Miller, MW. Prenatal exposure to ethanol delays the schedule and rate of migration of neurons to rat somatosensory cortex. In Fifth Congress of the International Society for Biomedical Research on Alcoholism (ISBRA). Denver: ISBRA, 1990.Google Scholar
Holzman, C, Paneth, N, Little, R, et al. Perinatal brain injury in premature infants born to mothers using alcohol in pregnancy. Pediatrics 1995; 95: 6673.Google Scholar
Armant, DR, Saunders, DE. Exposure of embryonic cells to alcohol: contrasting effects during preimplantation and postimplantation development. Semin Perinatol 1996; 20: 127–39.Google Scholar
Ahlgren, SC, Thakur, V, Bronner-Fraser, M. Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. Proc Natl Acad Sci USA 2002; 99: 10476–81.Google Scholar
Peng, Y, Yang, PH, Ng, SSM, et al. A critical role of Pax6 in alcohol induced fetal microcephaly. Neurobiol Dis 2004; 16: 370–6.Google Scholar
Chrisman, K, Kenney, R, Comin, J, et al. Gestational ethanol exposure disrupts the expression of Fgf8 and Sonic hedgehog during limb patterning. Birth Defects Res A Clin Mol Teratol 2004; 70: 163–71.Google Scholar
Veazey, KJ, Parnell, SE, Miranda, RC, Golding, MC. Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. Epigenet Chromatin 2015; 8: 39.Google Scholar
Kleiber, ML, Diehl, EJ, Laufer, BI, et al. Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. Front Genet 2014; 5: 161.Google Scholar
Mead, EA, Sarkar, DK. Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. Front Genet 2014; 5: 154.CrossRefGoogle ScholarPubMed
Druse, MJ, Kuo, A, Tajuddin, N. Effects of in utero ethanol exposure on the developing serotonergic system. Alcohol Clin Exp Res 1991; 15: 678–84.Google Scholar
Pinazo-Duran, MD, Renau-Piqueras, J, Guerri, C. Developmental changes in the optic nerve related to ethanol consumption in pregnant rats: analysis of the ethanol-exposed optic nerve. Teratology 1993; 48: 305–22.Google Scholar
Church, MW, Gerkin, KP. Hearing disorders in children with fetal alcohol syndrome: findings from case reports. Pediatrics 1988; 82: 147–54.Google Scholar
Syslak, PH, Nathaniel, EJH, Novak, C, et al. Fetal alcohol effects on the postnatal development of the rat myocardium:an ultrastructural and morphometric analysis. Exp Mol Pathol 1994; 60: 158–72.Google Scholar
Gage, JC, Sulik, KK. Pathogenesis of ethanol-induced hydronephrosis and hydroureter as demonstrated following in vivo exposure of mouse embryos. Teratology 1991; 44: 299312.Google Scholar
Autti-Rämö, I, Fagerlund, A, Ervalahti, N, et al. Fetal alcohol spectrum disorders in Finland: clinical delineation of 77 older children and adolescents. Am J Med Genet A 2006; 140: 137–43.Google Scholar
Day, NL, Richardson, G, Robles, N, et al. Effect of prenatal alcohol exposure on growth and morphology of offspring at 8 months of age. Pediatrics 1990; 85: 748–52.Google Scholar
Breese, CR, D’Costa, A, Ingram, RL, et al. Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure:relationship to somatic growth. J Pharmacol Exp Ther 1993; 264: 448–57.Google Scholar
Mauceri, HJ, Lee, W, Conway, S. Effect of ethanol on insulin-like growth factor-II release from fetal organs. Alcohol Clin Exp Res 1994; 18: 3541.Google Scholar
Guo, W, Gregg, JP, Fonkalsrud, EW. Effect of maternal ethanol intake on fetal rabbit gastrointestinal development. J Pediatr Surg 1994; 29: 1030–4.Google Scholar
American College of Obstetricians and Gynecologists. Breastfeeding: Maternal and Infant Aspects (Educational Bulletin Number 258). Washington, DC: ACOG, 2000.Google Scholar
Little, RE, Anderson, KW, Ervin, CH, et al. Maternal alcohol use during breast-feeding and infant mental and motor development at one year. N Engl J Med 1989; 321: 425–30.Google Scholar
Graham, JM, Hanson, JW, Darby, BL, et al. Independent dysmorphology evaluations at birth and 4 years of age for children exposed to varying amounts of alcohol in utero. Pediatrics 1988; 81: 772–8.Google Scholar
Streissguth, AP. The behavioral teratology of alcohol: performance, behavioral, and intellectual deficits in prenatally exposed children. In West, JR, ed., Alcohol and Brain Development. New York:Oxford University Press, 1986: 344.Google Scholar
Streissguth, AP, Aase, JM, Clarren, SK, et al. Fetal alcohol syndrome in adolescents and adults. JAMA 1991; 265: 1961–7.Google Scholar
Kirkland, SA, Dodds, LA, Brosky, G. The natural history of smoking during pregnancy among women in Nova Scotia. CMAJ 2000; 163: 281–2.Google ScholarPubMed
Tong, VT, England, LJ, Dietz, PM, Asare, LA. Smoking patterns and use of cessation interventions during pregnancy. Am J Prevent Med 2008; 35: 327–33.Google Scholar
Tong, VT, Jones, JR, Dietz, PM, et al. Trends in smoking before, during, and after pregnancy: pregnancy risk assessment monitoring system (PRAMS), United States, 31 Sites, 2000–2005. MMWR Surveill Summ 2009; 58: 129.Google Scholar
Lee, LJ, Lupo, PJ. Maternal smoking during pregnancy and the risk of congenital heart defects in offspring: a systematic review and metaanalysis. Pediatr Cardiol 2013; 34: 398407.Google Scholar
Secker-Walker, RH, Vacek, PM, Flynn, BS, et al. Smoking in pregnancy, exhaled carbon monoxide, and birth weight. Obstet Gynecol 1997; 89: 648–53.Google Scholar
Visnjevac, V, Mikov, M. Smoking and carboxyhemoglobin concentrations in mothers and their newborn infants. Toxicology 1986; 5: 175–7.Google Scholar
Jazayeri, A, Tsibris, JCM, Spellacy, WN. Umbilical cord plasma erythropoietin levels in pregnancies complicated by maternal smoking. Am J Obstet Gynecol 1998; 178: 433–5.Google Scholar
Jordanov, JS. Cotinine concentrations in amniotic fluid and urine of smoking, passive smoking and non-smoking pregnant women at term and in the urine of their neonates on the 1st day of life. Eur J Pediatr 1990; 149: 734–7.Google Scholar
Bernstein, IM, Plocienik, K, Stahle, S, et al. Impact of maternal cigarette smoking on fetal growth and body composition. Am J Obstet Gynecol 2000; 183: 883–6.Google Scholar
Law, KL, Stroud, LR, LaGasse, LL, et al. Smoking during pregnancy and newborn neurobehavior. Pediatrics 2003; 111: 1318–23.Google Scholar
Bardy, AH, Seppälä, T, Lillsunde, P, et al. Objectively measured tobacco exposure during pregnancy: neonatal effects and relation to maternal smoking. Br J Obstet Gynaecol 1993; 100: 721–6.Google Scholar
Bernstein, IM, Mongeon, JA, Badger, GJ, et al. Maternal smoking and its association with birth weight. Obstet Gynecol 2005; 106: 986–91.Google Scholar
Cliver, SP, Goldenberg, RL, Cutter, GR, et al. The effect of cigarette smoking on neonatal anthropometric measurements. Obstet Gynecol 1995; 85: 625–30.Google Scholar
Hermann, M, King, K, Weitzman, M. Prenatal tobacco smoke and postnatal secondhand smoke exposure and child neurodevelopment. Curr Opin Pediatr 2008; 20: 184–90.Google Scholar
Bada, HS, Das, A, Bauer, CR, et al. Low birth weight and preterm births: etiologic fraction attributable to prenatal drug exposure. J Perinatol 2005; 25: 631–7.CrossRefGoogle ScholarPubMed
Resnik, R, Brink, GW, Wilkes, M. Catecholamine-mediated reduction in uterine blood flow after nicotine infusion in the pregnant ewe. J Clin Invest 1979; 63: 1133–6.Google Scholar
Burton, GJ, Palmer, ME, Dalton, KJ. Morphometric differences between the placental vasculature of non-smokers, smokers and ex-smokers. Br J Obstet Gynaecol 1989; 96: 907–15.Google Scholar
Larsen, LG, Clausen, HV, Jonsson, L. Stereologic examination of placentas from mothers who smoke during pregnancy. Am J Obstet Gynecol 2002; 186: 531–7.Google Scholar
Gabrial, R, Alsat, E, Evain-Brion, D. Alteration of epidermal growth factor receptor in placental membranes of smokers: relationship with intrauterine growth retardation. Am J Obstet Gynecol 1994; 170: 1238–43.Google Scholar
Slotkin, TA, McCook, EC, Lappi, SE, et al. Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally. Dev Brain Res 1992; 68: 233–9.Google Scholar
Khoury, MJ, Gomez-Frias, M, Mulinare, J. Does maternal cigarette smoking during pregnancy cause cleft lip and palate in offspring? Am J Dis Child 1989; 143: 333–7.Google Scholar
Sullivan, PM, Dervan, LA, Reiger, S, et al. Risk of congenital heart defects in the offspring of smoking mothers: a population-based study. J Pediatr 2015; 166: 978–84.Google Scholar
Hacksaw, A, Rodeck, C, Boniface, S. Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 malformed cases and 11.7 million controls. Hum Reprod Update 2011; 17: 589604.Google Scholar
Ananth, CV, Savitz, DA, Luther, ER. Maternal cigarette smoking as a risk factor for placental abruption, placenta previa, and uterine bleeding in pregnancy. Am J Epidemiol 1996; 144: 881–9.Google Scholar
Castles, A, Adams, K, Melvin, CL, et al. Effects of smoking during pregnancy: five meta-analyses. Am J Prevent Med 1999; 16: 208–15.Google Scholar
Naeye, RL. Abruptio placentae and placenta previa: frequency, perinatal mortality, and cigarette smoking. Obstet Gynecol 1980; 55: 701–4.Google Scholar
Ananth, CV, Getahun, D, Peltier, MR, et al. Placental abruption in term and preterm gestations: evidence for heterogeneity in clinical pathways. Obstet Gynecol 2006; 107: 785–92.Google Scholar
Zdravkovic, T, Genbacev, O. McMaster, MT, Fisher, SJ. The adverse effects of maternal smoking on the human placenta: a review. Placenta 2005; 26A: S81–6.Google Scholar
Usta, IM, Hobeika, EM, Musa, AA, et al. Placenta previa-accreta: risk factors and complications. Am J Obstet Gynecol 2005; 193: 1045–9.Google Scholar
Nabet, C, Ancel, PY, Burguet, A, et al. Smoking during pregnancy and preterm birth according to obstetric history: French national perinatal surveys. Paediatr Perinat Epidemiol 2005; 19: 8896.Google Scholar
Salihu, HM, Sharma, PP, Getahun, G. Prenatal tobacco use and risk of stillbirth: a case-control and bidirectional case–crossover study. Nicotine Tobac Res 2008; 10: 159–66.Google Scholar
Varner, MW, Silver, RM, Rowland, CJ, et al. Association between stillbirth and illicit drug use and smoking during pregnancy. Obstet Gynecol 2014; 123: 113–25.Google Scholar
Marufu, TC, Ahankari, A, Coleman, T, Lewis, S. Maternal smoking and the risk of stillbirth: systemic review and meta-analysis. BMS Public Health 2015; 15: 239–53.Google Scholar
Flenady, V, Koopmans, L, Middleton, P, et al. Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis. Lancet 2011; 377: 1331–40.Google Scholar
Arbeille, P, Bosc, M, Vaillant, MC, et al. Nicotine-induced changes in the cerebral circulation in ovine fetuses. Am J Perinatol 1992; 79: 645–8.Google Scholar
Lei, F, Yan, X, Zhao, F. Impairment of central chemoreception in neonatal rats induced by maternal cigarette smoke exposure during pregnancy. PLoS One 2015; 10: e0137362.Google Scholar
Franco, P, Groswasser, J, Hassid, S, et al. Prenatal exposure to cigarette smoking is associated with a decrease in arousal in infants. J Pediatr 1999; 135: 34–8.Google Scholar
Hoffman, HJ, Hillman, LS. Epidemiology of the sudden infant death syndrome: maternal, neonatal, and postneonatal risk factors. Clin Perinatol 1992; 19: 717–37.Google Scholar
Takashima, S, Armstrong, D, Becker, LE, et al. Cerebral hypoperfusion in the sudden infant death syndrome, brainstem gliosis and vasculature. Ann Neurol 1978; 4: 257–62.Google Scholar
Mezzacappa, E, Buckner, JC, Earls, F. Prenatal cigarette exposure and infant learning stimulation as predictors of cognitive control in childhood. Dev Sci 2011; 14: 881–91.Google Scholar
Drews, CD, Murphy, CC, Yeargin-Allsop, M, et al. The relationship between idiopathic mental retardation and maternal smoking during pregnancy. Pediatrics 1996; 97: 547–53.Google Scholar
Olds, DL, Henderson, CR, Tatelbaum, R. Intellectual impairment in children of women who smoke cigarettes during pregnancy. Pediatrics 1994; 93: 221–7.CrossRefGoogle ScholarPubMed
Cornelius, MD, De Genna, NM, Leech, SL, et al. Effects of prenatal cigarette smoke exposure on neurobehavioral outcomes in 10-year-old children of adolescent mothers. Neurotoxicol Teratol 2011; 33: 137–44.Google Scholar
Cornelius, MD, Goldschmidt, L, De Genna, NM, Larkby, C. Long-term effects of prenatal cigarette smoke exposure on behavior dysregulation among 14-year-old offspring of teenage mothers. Matern Child Health J 2012; 16: 694705.Google Scholar
Cornelius, MD, Goldschmidt, L, Day, NL. Prenatal cigarette smoking: long term effects on young adult behavior problems and smoking behavior. Neurotoxicol Teratol 2012; 34: 554–9.Google Scholar
Ernst, M, Moolchan, ET, Robisnon, ML. Behavioral and neural consequences of prenatal exposure to nicotine. J Am Acad Child Adolesc Psychiatry 2001; 40: 630–41.Google Scholar
Polanska, K, Jurewicz, J, Hanke, W. Smoking and alcohol drinking during pregnancy as the risk factors for poor child neurodevelopment: a review of epidemiological studies. Int J Occup Med Environ Health 2015; 28: 419–43.Google Scholar
John, EM, Savitz, DA, Sandler, DP. Prenatal exposure to parents’ smoking and childhood cancer. Am J Epidemiol 1991; 133: 123–32.Google Scholar
Charlton, A. Children and passive smoking: a review. J Fam Pract 1994; 38: 267–77.Google Scholar
Paulson, RB, Shanfeld, J, Mullet, D, et al. Prenatal smokeless tobacco effects on the rat fetus. J Craniofac Genet Dev Biol 1994; 14: 1625.Google Scholar
Inamdar, AS, Croucher, RE, Chokhandre, MK, et al. Maternal smokeless tobacco use in pregnancy and adverse heatlh outcomes in newborns: a systematic review. Nicotine Tobac Res 2015; 17: 1058–66.Google Scholar
England, LJ, Kim, SY, Shapiro-Mendoza, CK, et al. Effects of maternal smokeless tobacco use on selected pregnancy outcomes in Alaska Native women: a case-control study. Acta Obstet Gynaecol Scand 2013; 92: 648–55.Google Scholar
Gunnerbeck, A, Edstedt Bonamy, AK, Wikstrom, AK, et al. Maternal snuff use and smoking and the risk of oral cleft malformations: a population-based cohort study. PLoS One 2014; 9: e84715.Google Scholar
Gunnerbeck, A, Wikstrom, AK, Edstedt Bonamy, AK, et al. Relationship of maternal snuff and cigarette smoking with neonatal apnea. Pediatrics 2011; 128: 503–9.Google Scholar
Weaver, M, Breland, A, Spindle, T, Eissenberg, T. Clinical case conference electronic cigarettes: a review of safety and clinical issues. J Addict Med 2014; 8: 234–40.Google Scholar
Breland, A, Spindle, T, Weaver, M, Eissenberg, T. Science and electronic cigarettes: current data, future needs. J Addict Med 2014; 8: 223–33.Google Scholar
Suter, MA, Mastrobattista, J, Sachs, M, Aagaard, K. Is there evidence for potential harm of electronic cigarette use in pregnancy? Birth Defects Res A Clin Mol Teratol 2015; 103: 186–95.Google Scholar
Mark, KS, Farquhar, B, Chisolm, MS, et al. Knowledge, attitudes, and practice of electronic cigarette use among pregnant women. J Addict Med 2015; 9: 266–72.Google Scholar
Ostrea, EM, Knapp, DK, Romera, A, et al. Meconium analysis to assess fetal exposure to nicotine by active and passive maternal smoking. J Pediatr 1994; 124: 471–6.Google Scholar
Lee, BO, Hong, YC, Park, H, et al. Secondhand smoke exposure during pregnancy and infantile development. Environ Res 2011; 111: 539–44.Google Scholar
Makin, J, Fried, PA, Watkinson, B. A comparison of active and passive smoking during pregnancy: long-term effects. Neurotoxicol Teratol 1991; 13: 512.Google Scholar
Liu, J, Leung, PW, McCauley, L, et al. Mother’s environmental tobacco smoke exposure during pregnancy and externalizing behavior problems in children. Neurotoxicology 2013; 34: 167–74.Google Scholar
Witschi, H, Lundgaard, SM, Rajini, P, et al. Effects of exposure to nicotine and to sidestream smoke on pregnancy outcome in rats. Toxicol Lett 1994; 71: 279–86.Google Scholar
Davis, DL. Paternal smoking and fetal health. Lancet 1991; 337: 123.Google Scholar
Klonoff-Cohen, HS, Edelstein, SL, Lefkowitz, ES, et al. The effect of passive smoking and tobacco exposure through breast milk on sudden infant death syndrome. JAMA 1995; 273: 795–8.Google Scholar
Zhou, S, Rosenthal, DG, Sherman, S, et al. Physical, behavioral, and cognitive effects of prenatal tobacco and postnatal secondhand smoke exposure. Curr Probl Pediatr Adolesc Health Care 2014; 44: 219–41.Google Scholar
Selden, BS, Clark, RF, Curry, SC. Marijuana. Emerg Med Clin North Am 1990; 8: 8527–39.Google Scholar
Wu, TC, Tashkin, DP, Djahed, B, et al. Pulmonary hazards of smoking marijuana as compared with tobacco. N Engl J Med 1988; 318: 347–51.Google Scholar
Cornelius, MD, Taylor, PM, Geva, D, et al. Prenatal tobacco and marijuana use among adolescents: effects on offspring gestational age, growth, and morphology. Pediatrics 1995; 95: 738–43.Google Scholar
English, DR, Hulse, GK, Milne, E, et al. Maternal cannabis use and birth weight: a meta-analysis. Addiction 1997; 92: 1553–60.Google Scholar
Fried, PA, Watkinson, B, Gray, R. Growth from birth to early adolescence in offspring prenatally exposed to cigarettes and marijuana. Neurotoxicol Teratol 1999; 21: 513–25.Google Scholar
Fried, PA, Makin, JE. Neonatal behavioral correlates of prenatal exposure to marijuana, cigarettes and alcohol in a low risk population. Neurotoxicol Teratol 1987; 9: 17.Google Scholar
Dahl, RE, Scher, MS, Williamson, DE, et al. A longitudinal study of prenatal marijuana use: effects on sleep and arousal at age 3 years. Arch Pediatr Adolesc Med 1995; 149: 145–50.Google Scholar
Fried, PA. Prenatal exposure to marijuana and tobacco during infancy, early and middle childhood: effects and an attempt at synthesis. Arch Toxicol Suppl 1995; 17: 233–60.Google Scholar
Fried, PA. The Ottawa Prenatal Prospective Study (OPPS): methodologic issues and findings. It’s easy to throw the baby out with the bathwater. Life Sci 1995; 56: 2159–68.Google Scholar
Campolongo, P, Trezza, V, Palmery, M, et al. Developmental exposure to cannabinoids causes subtle and enduring neurofunctional alterations. Int Rev Neurobiol 2009; 85: 117–33.Google Scholar
Schneider, M. Cannabis use in pregnancy and early life and its consequences: animal models. Eur Arch Psychiatry Clin Neurosci 2009; 259: 383–93.CrossRefGoogle ScholarPubMed
DiNieri, JA, Wang, X, Szutorisz, H, et al. Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring. Biol Psychiatry 2011; 70: 763–9.Google Scholar
Spano, MS, Ellgren, M, Wang, X, Hurd, YL. Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood. Biol Psychiatry 2007; 61: 554–63.Google Scholar
Farrar, HC, Kearns, GL. Cocaine: clinical pharmacology and toxicology. J Pediatr 1989; 115: 665–75.Google Scholar
Bailey, DN. Cocaine and cocaethylene binding to human placenta in vitro. Am J Obstet Gynecol 1997; 177: 527–31.Google Scholar
Jones, KL. Developmental pathogenesis of defects associated with prenatal cocaine exposure: fetal vascular disruption. Clin Perinatol 1991; 18: 139–46.CrossRefGoogle ScholarPubMed
Singer, LT, Arendt, R, Minnes, S, et al. Cognitive and motor outcomes of cocaine-exposed infants. JAMA. 2002; 287(15): 1952–60.CrossRefGoogle ScholarPubMed
Frank, DA, Augustyn, M, Knight, WG, et al. Growth, development, and behavior in early childhood following prenatal cocaine exposure: a systematic review. JAMA. 2001; 285(12): 1613–25.Google Scholar
Bandstra, ES, Morrow, CE, Anthony, JC, et al. Intrauterine growth of full-term infants: impact of prenatal cocaine exposure. Pediatrics 2001; 108: 1309–19.Google Scholar
Bateman, DA, Chiriboga, CA. Dose-response effect of cocaine on newborn head circumference. Pediatrics 2000; 106: e33.Google Scholar
Kuhn, L, Kline, J, Ng, S, et al. Cocaine use during pregnancy and intrauterine growth retardation: new insights based on maternal hair tests. Am J Epidemiol 2000; 152: 112–19.Google Scholar
Dinsmoor, MJ, Irons, SJ, Christmas, JT. Preterm rupture of the membranes associated with recent cocaine use. Am J Obstet Gynecol 1994; 171: 305–9.Google Scholar
Kliegman, RM, Madura, D, Kiwi, R, et al. Relation of maternal cocaine use to the risks of prematurity and low birth weight. J Pediatr 1994; 124: 751–6.Google Scholar
Iriye, BK, Bristow, RE, Hsu, CD, et al. Uterine rupture associated with recent antepartum cocaine abuse. Obstet Gynecol 1994; 83: 840–1.Google Scholar
Macones, GA, Sehdev, HM, Parry, S, et al. The association between maternal cocaine use and placenta previa. Am J Obstet Gynecol 1997; 177: 1097–100.Google Scholar
Czyrko, C, Del Pin, CA, O’Neill, JA, et al. Maternal cocaine abuse and necrotizing enterocolitis: outcome and survival. J Pediatr Surg 1991; 26: 414–18.Google Scholar
Büyükünal, C, Kiliç, N, Dervisoglu, S, et al. Maternal cocaine abuse resulting in necrotizing enterocolitis: an experimental study in a rat model. Acta Paediatr 1994; 396: 91–3.Google Scholar
Chasnoff, IJ, Bussey, ME, Savich, R, et al. Perinatal cerebral infarction and maternal cocaine use. J Pediatr 1986; 108: 456–9.Google Scholar
Singer, LT, Yamashita, TS, Hawkins, S, et al. Increased incidence of intraventricular hemorrhage and developmental delay in cocaine-exposed, very low birth weight infants. J Pediatr 1994; 124: 765–71.Google Scholar
Sims, ME, Walther, FJ. Antenatal brain injury and maternal cocaine use. J Perinatol 1989; 9: 349–50.Google Scholar
Behnke, M, Eyler, FD, Conlon, M, et al. Incidence and description of structural brain abnormalities in newborns exposed to cocaine. J Pediatr 1998; 132: 291–4.Google Scholar
Mott, SH, Packer, RJ, Soldin, SJ. Neurologic manifestations of cocaine exposure in childhood. Pediatrics 1994; 93: 557–60.Google Scholar
Chen, C, Duara, S, Neto, GS, et al. Respiratory instability in neonates with in utero exposure to cocaine. J Pediatr 1991; 119: 111–13.Google Scholar
Tronick, EZ, Frank, DA, Cabral, H, et al. Late dose-response effects of prenatal cocaine exposure on newborn neurobehavioral performance. Pediatrics 1996; 98: 7683.Google Scholar
Chan, K, Dodd, PA, Day, L, et al. Fetal catecholamine, cardiovascular, and neurobehavioral responses to cocaine. Am J Obstet Gynecol 1992; 167: 1616–23.Google Scholar
Knapp, S, Mandell, AJ. Narcotic drugs: effect on the serotonin biosynthetic systems of the brain. Science 1972; 177: 1209–11.Google Scholar
Durand, DJ, Espinoza, AM, Nickerson, BG. Association between prenatal cocaine exposure and sudden infant death syndrome. J Pediatr 1990; 117: 909–11.CrossRefGoogle ScholarPubMed
Bauchner, H, Zuckerman, B, McClain, M, et al. Risk of sudden infant death syndrome among infants with in utero exposure to cocaine. J Pediatr 1988; 113: 831–4.Google Scholar
Mayes, LC, Granger, RH, Frank, MA, et al. Neurobehavioral profiles of neonates exposed to cocaine prenatally. Pediatrics 1993; 91: 778–83.Google Scholar
Eisen, LN, Field, TM, Bandstra, ES, et al. Perinatal cocaine effects on neonatal stress behavior and performance on the Brazelton scale. Pediatrics 1991; 88: 477–80.Google Scholar
Eyler, FD, Behnke, M, Conlon, M, et al. Birth outcome from a prospective, matched study of prenatal crack/cocaine use. I. Interactive and dose effects on health and growth. Pediatrics 1998; 101: 229–37.Google Scholar
Eyler, FD, Behnke, M, Conlon, M, et al. Birth outcome from a prospective, matched study of prenatal crack/cocaine use. II. Interactive and dose effects on neurobehavioral assessment. Pediatrics 1998; 101: 237–41.Google Scholar
Frank, DA, Augustyn, M, Knight, WG, et al. Growth, development, and behavior in early childhood following prenatal cocaine exposure: a systematic review. JAMA 2001; 285: 1613–25.Google Scholar
Roland, EH, Volpe, JJ. Effect of maternal cocaine use on the fetus and newborn: review of the literature. Pediatr Neurosci 1989; 15: 8894.Google Scholar
Oro, A, Dixon, S. Perinatal cocaine and methamphetamine exposure: maternal and neonatal correlates. J Pediatr 1987; 111: 571–8.Google Scholar
Chasnoff, IJ, Lewis, DE, Squires, L. Cocaine intoxication in a breast-fed infant. Pediatrics 1987; 80: 836–8.Google Scholar
Chaney, NE, Franke, J, Waddington, WB. Cocaine convulsions in a breast-feeding baby. J Pediatr 1988; 112: 134–5.Google Scholar
Hulse, GK, Milne, E, English, DR, et al. The relationship between maternal use of heroin and methadone and infant birth weight. Addiction 1997; 92: 1571–9.Google Scholar
Barg, J, Rius, A, Bem, WT, et al. Differential development of beta-endorphin and mu-opioid binding sites in mouse brain. Dev Brain Res 1992; 66: 71–6.Google Scholar
Suguihara, C, Bancalari, E. Substance abuse during pregnancy: effects on respiratory function in the infant. Semin Perinatol 1991; 15: 302–9.Google Scholar
Olson, GD, Lees, MH. Ventilatory response to carbon dioxide of infants following chronic prenatal methadone exposure. J Pediatr 1980; 96: 983–9.Google Scholar
Bunikowski, R, Grimmer, I, Heiser, A, et al. Neurodevelopmental outcome after prenatal exposure to opiates. Eur J Pediatr 1998; 157: 724–30.Google Scholar
Smialek, JE, Monforte, JR, Aronow, R, et al. Methadone deaths in children: a continuing problem. JAMA 1977; 238: 2516–17.CrossRefGoogle ScholarPubMed
Committee on Drugs, American Academy of Pediatrics. Transfer of drugs and other chemicals into human milk. Pediatrics 1989; 84: 924–36.Google Scholar
Guo, X, Spencer, JW, Suess, PE, et al. Cognitive brain potential alterations in boys exposed to opiates: in utero and lifestyle comparisons. Addict Behav 1994; 19: 429–41.Google Scholar
Hunt, RW, Tzioumi, D, Collins, E, Jeffery, HE. Adverse neurodevelopmental outcome of infants exposed to opiate in-utero. Early Hum Dev 2008; 84: 2935.Google Scholar
Hickey, JE, Suess, PE, Newlin, DB, et al. Vagal tone regulation during sustained attention in boys exposed to opiates in utero. Addict Behav 1995; 20: 4359.Google Scholar
Ornoy, A, Michailevskaya, V, Lukashov, I, et al. The developmental outcome of children born to heroin-dependent mothers, raised at home or adopted. Child Abuse Negl 1996; 20: 385–96.Google Scholar
Ornoy, A, Segal, J, Bar-Hamburger, R, Greenbaum, C. Developmental outcome of school-age children born to mothers with heroin dependency: importance of environmental factors. Dev Med Child Neurol 2001; 43: 668–75.Google Scholar
Idänpäan-Heikkilä, JE, Jouppila, PI, Puolakka, JO, et al. Placental transfer and fetal metabolism of diazepam in early pregnancy. Am J Obstet Gynecol 1971; 109: 1011–16.Google Scholar
Laegreid, L, Olegärd, R, Walström, J, et al. Teratogenic effects of benzodiazepine use during pregnancy. J Pediatr 1989; 114: 126–31.Google Scholar
Wikner, BN, Stiller, C-O, Bergman, U, et al. Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: neonatal outcome and congenital malformations. Pharmacoepidemiol Drug Saf 2007; 16: 1203–10.Google Scholar
Eros, E, Czeizel, AE, Rockenbauer, M, et al. A population-based case control teratologic study of nitrazepam, medazepam, tofisopam, alprazolum and clonazepam treatment during pregnancy. Eur J Obstet Gynecol Reprod Biol 2002; 101: 147–54.Google Scholar
Bellantuono, C, Tofani, S, Di Sciascio, G, Santone, G. Benzodiazepine exposure in pregnancy and risk of major malformations: a critical overview. Gen Hosp Psychiatry 2013; 35: 38.Google Scholar
Ban, L, West, J, Gibson, JE, Fiaschi, L, et al. First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS One 2014; 9: e100996.Google Scholar
Okun, ML, Ebert, R, Saini, B. A review of sleep-promoting medications used in pregnancy. Am J Obstet Gynecol 2015; 212: 428–41.Google Scholar
Iqbal, MM, Sobhan, T, Ryals, T. Effects of commonly used benzodiazepines on the fetus, the neonate, and the nursing infant. Psychiatr Serv 2002; 53: 3949.Google Scholar
Kallen, B, Reis, M. Neonatal complications after maternal concomitant use of SSRI and other central nervous system active drugs during the second or third trimester of pregnancy. J Clin Psychopharmacol 2012; 32: 608–14.Google Scholar
Dessens, AB, Cohen-Kettenis, PT, Mellenbergh, GJ, et al. Association of prenatal phenobarbital and phenytoin exposure with small head size at birth and with learning problems. Acta Paediatr 2000; 89: 533–41.Google Scholar
Verrotti, A, Scaparrotta, A, Cofini, M, et al. Developmental neurotoxicity and anticonvulsant drugs: a possible link. Reprod Toxicol 2014; 48: 7280.Google Scholar
Browne, ML, Van Zutphen, AR, Botto, LD, et al. Maternal butalbital use and selected defects in the national birth defects prevention study. Headache 2014; 54: 5466.Google Scholar
Rementeria, JL, Bhatt, K. Withdrawal symptoms in neonates from intrauterine exposure to diazepam. J Pediatr 1977; 90: 123–6.Google Scholar
Izquierdo, LA, Yonke, N. Fetal surveillance in late pregnancy and during labor. Obstet Gynecol Clin N Am 2014; 41: 307–15.Google Scholar
Ladhani, NN, Shah, PS, Murphy, KE. Prenatal amphetamine exposure and birth outcomes: a systematic review and metaanalysis. Am J Obstet Gyncol 2011; 205(219): e17.Google Scholar
Stek, AM, Baker, RS, Fisher, BK, et al. Fetal responses to maternal and fetal methamphetamine administration in sheep. Am J Obstet Gynecol 1995; 173: 1592–8.Google Scholar
Shah, R, Diaz, SD, Arria, A, et al. Prenatal methamphetamine exposure and short-term maternal and fetal outcomes. Am J Perinatol 2012; 29: 391400.Google Scholar
Plessinger, MA. Prenatal exposure to amphetamines: risks and adverse outcomes in pregnancy. Obstet Gynecol Clin North Am 1998; 25: 119–38.Google Scholar
Ganapathy, V, Ramamoorthy, S, Leibach, FH. Transport and metabolism of monoamines in the human placenta. Trophoblast Res 1993; 7: 3551.Google Scholar
Ganapathy, VV, Prasad, PD, Ganapathy, ME, Leibach, FH. Drugs of abuse and placental transport. Adv Drug Deliv Rev 1999; 38: 99110.Google Scholar
Wright, TE, Schuetter, R, Tellei, J, Sauvage, L. Methamphetamines and pregnancy outcome. J Addict Med 2015; 9: 111–17.Google Scholar
Bottalico, B, Larson, I, Brodszicki, J, et al. Norepinephrine transporter (NET), serotonin transporter (SERT), vesicular monoamine transporter (VMAT2) and organic cation transporters (OCT1, 2 and EMT) in human placenta from pre-eclamptic and normotensive pregnancies. Placenta 2004; 25: 518–29.Google Scholar
Ganapathy, V. Drugs of abuse and human placenta. Life Sci 2011; 88: 926–30.Google Scholar
Gorman, MC, Orme, KS, Nguyen, NT, et al. Outcomes in pregnancies complicated by methamphetamine use. Am J Obstet Gynecol 2014; 211(429): e17.Google Scholar
Geary, FH, Turnquest Wells, MA. Management of the patient in labor who has abused substances. Clin Obstet Gynecol 56: 166–72.Google Scholar
Ericksson, M, Larsson, C, Zetterström, R. Amphetamine addiction and pregnancy. Acta Obstet Gynaecol Scand 1981; 60: 253–9.Google Scholar
Arria, AM, Derauf, C, LaGasse, LL, et al. Methamphetamine and other substance use during pregnancy: preliminary estimates from the infant development, environment, and lifestyle (IDEAL) study. Matern Child Health J 2006; 10: 293302.Google Scholar
Nasif, FJ, Cuadra, GR, Ramirez, OA. Permanent alteration of cerebral noradrenergic system by prenatally administered amphetamine. Brain Res Dev Brain Res 1999; 112: 181–8.Google Scholar
Tavares, MA, Silva, MC. Differential effects of prenatal exposure to cocaine and amphetamine on growth parameters and morphometry of the prefrontal cortex in the rat. Ann NY Acad Sci 1996; 801: 256–73.Google Scholar
Tavares, MA, Silva, MC, Silva-Araujo, A, et al. Effects of prenatal exposure to amphetamine in the medial prefrontal cortex of the rat. Int J Dev Neurosci 1996; 14: 585–96.Google Scholar
Chang, L, Smith, LM, LoPresti, C, et al. Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure. Psychiatry Res 2004; 132: 95106.Google Scholar
Dixon, SD, Bejar, R. Echoencephalographic findings in neonates associated with maternal cocaine and methamphetamine use: incidence and clinical correlates. J Pediatr 1989; 115: 770–8.Google Scholar
McElhatton, PR, Pughe, KR, Evans, C, et al. Is exposure to amphetamine-like drugs in pregnancy associated with malformations? J Toxicol Clin Toxicol 2000; 38: 195–6.Google Scholar
Torfs, CP, Velie, EM, Oechsli, FW, et al. A population-based study of gastroschisis: demographic, pregnancy, and lifestyle risk factors. Teratology 1994:50: 4453.Google Scholar
Holbrook, BD, Rayburn, WF. Teratogenic risks from exposure to illicit drugs. Obstet Gynecol Clin North Am 2014; 41: 229–39.Google Scholar
Forrester, MB, Merz, RD. Risk of selected birth defects with prenatal illicit drug use, Hawaii, 1986–2002. J Toxicol Environ Health A 2007; 70: 718.Google Scholar
Little, BB, Snell, LM, Gilstrap, LC. Methamphetamine abuse during pregnancy: outcome and fetal effects. Obstet Gynecol 1988; 72: 541–4.Google Scholar
Oei, J, Abdel-Latif, ME, Clark, R, et al. Short-term outcomes of mothers and infants exposed to antenatal amphetamines. Arch Dis Child Fetal Neonatal Ed 2010; 95: F3641.Google Scholar
Nguyen, D, Smith, LM, LaGasse, LL, et al. Intrauterine growth of infants exposed to prenatal methamphetamine: results from the infant development, environment, and lifestyle study. J Pediatr 2010; 157: 337–9.Google Scholar
Smith, LM, LaGasse, LL, Derauf, C, et al. The infant development, environment, and lifestyle study: effects of prenatal methamphetamine exposure, polydrug exposure, and poverty on intrauterine growth. Pediatrics 2006; 118: 1149–56.Google Scholar
Oro, AS, Dixon, SP. Perinatal cocaine and methamphetamine exposure: maternal and neonatal correlates. J Pediatr 1987; 111: 571–8.Google Scholar
Smith, LM, Diaz, S, LaGasse, LL, et al. Developmental and behavioral consequences of prenatal methamphetamine exposure: a review of the infant development, environment, and lifestyle (IDEAL) study. Neurotoxicol Teratol 2015; 51: 3544.Google Scholar
Kiblawi, ZN, Smith, LM, Diaz, SD, et al. Prenatal methamphetamine exposure and neonatal and infant neurobehavioral outcome: results from the IDEAL study. Subst Abus 2014; 35: 6873.Google Scholar
Behnke, M, Smith, VC. Prenatal substance abuse: short- and long-term effects on the exposed fetus. Pediatrics 2013; 131: e1009–24.Google Scholar
Zabaneh, R, Smith, LM, LaGasse, LL, et al. The effects of prenatal methamphetamine exposure on childhood growth patterns from birth to 3 years of age. Am J Perinatol 2012; 29: 203–10.Google Scholar
Diaz, SD, Smith, LM, LaGasse, LL, et al. Effects of prenatal methamphetamine exposure on behavioral and cognitive findings at 7.5 years of age. J Pediatr 2014; 164: 1333–8.Google Scholar
Cernerud, L, Eriksson, M, Jonsson, B, et al. Amphetamine addiction during pregnancy: 14-year follow-up of growth and school performance. Acta Paediatr 1996; 85: 204–8.Google Scholar
LaGasse, LL, Derauf, C, Smith, LL, et al. Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics 2012; 129: 681–8.Google Scholar
Kwiatkowski, MA, Roos, A, Stein, DJ, et al. Effects of prenatal methamphetamine exposure: a review of cognitive and neuroimaging studies. Metab Brain Dis 2014; 29: 245–54.Google Scholar
Holbrook, BD, Rayburn, WF. Teratogenic risks from exposure to illicit drugs. Obstet Gynecol Clin North Am 2014; 41: 229–39.Google Scholar
Anderson, CE, Loomis, GA. Recognition and prevention of inhalant abuse. Am Fam Physician 2003; 68: 869–74.Google Scholar
Linden, CH. Volatile substances of abuse. Emerg Med Clin North Am 1990; 8: 559–78.Google Scholar
Scheeres, JJ, Chudley, AE. Solvent abuse in pregnancy: a perinatal perspective. J Obstet Gynaecol Can 2001; 24: 22–6.Google Scholar
Geary, FH, Turnquist Wells, MA. Management of the patient in labor who has abuse substances. Clin Obstet Gynecol 2013; 56: 166–72.Google Scholar
Jones, HE, Balster, RL. Inhalant abuse in pregnancy. Obstet Gynecol Clin North Am 1998; 25: 153–67.Google Scholar
Hannigan, JH, Bowen, SE. Reproductive toxicology and teratology of abused toluene. Syst Biol Reprod Med 2010; 56: 184200.Google Scholar
Ghantous, H, Danielsson, BRG. Placental transfer and distribution of toluene, xylene, and benzene and their metabolites during gestation in mice. Biol Res Pregnancy 1986; 7: 98105.Google Scholar
Stoltenbeurg-Didinger, G, Altenkirch, H, Wagner, M. Neurotoxicity of organic solvent mixtures: embryotoxicity and fetotoxicity. Neurotoxicol Teratol 1990; 12: 585–9.Google Scholar
Gospe, SM, Zhou, SS. Prenatal exposure to toluene results in abnormal neurogenesis and migration in rat somatosensory cortex. Pediatr Res 2000; 47: 362–8.Google Scholar
Gospe, SM, Zhou, SS. Toluene abuse embryopathy: longitudinal neurodevelopmental effects of prenatal exposure to toluene in rats. Reprod Toxicol 1998; 12: 119–26.Google Scholar
Bowen, SE, Hannigan, JH. Developmental toxicity of prenatal exposure to toluene. AAPS J 2006; 8: E419–24.Google Scholar
Bowen, SE, Batis, JC, Mohammadi, MH, Hannigan, JH. Abuse pattern of gestational toluene exposure and early postnatal development in rats. Neurotoxicol Teratol 2005; 27: 105–16.Google Scholar
Pearson, MA, Hoyme, HE, Seaver, LH, et al. Toluene embryopathy: delineation of the phenotype and comparison with fetal alcohol syndrome. Pediatrics 1994; 93: 211–15.Google Scholar
Arnold, GL, Kirby, RS, Langendoerfer, S, Wilkins-Haug, L. Toluene embryopathy: clinical delineation and developmental follow-up. Pediatrics 1994; 93: 216–20.Google Scholar
Bowen, SE. Two serious and challenging medical complications associated with volatile substance misuse: sudden sniffing death and fetal solvent syndrome. Subst Use Misuse 2011; 46: 6872.Google Scholar
Boynukalin, FK, Baykal, C. Prenatal diagnosis of multiple fetal anomalies in naphthalene-addicted pregnant women: a case report. Clin Exp Obstet Gynecol 2014; 41: 217–18.Google Scholar
Schutzman, DL, Frankenfield-Chernicoff, M, Clatterbaugh, HE, et al. Incidence of intrauterine cocaine exposure in a suburban setting. Pediatrics 1991; 88: 825–7.Google Scholar
Chasnoff, IJ, Landres, HJ, Barrett, ME. The prevalence of illicit-drug or alcohol use during pregnancy and discrepancies in mandatory reporting in Pinellas County, Florida. N Engl J Med 1990; 322: 1202–6.Google Scholar
Farrar, HC, Kearns, GL. Cocaine: clinical pharmacology and toxicology. J Pediatr 1989; 115: 665–75.Google Scholar
Ryan, RM, Wagner, CL, Schultz, JM, et al. Meconium analysis for improved identification of infants exposed to cocaine in utero. J Pediatr 1994; 125: 435–40.Google Scholar
Saitoh, M, Uzuka, M, Sakamoto, M. Rate of hair growth. Adv Biol Skin 1969; 9: 183201.Google Scholar
Baumgartner, WA, Hill, VA, Bland, WH. Hair analysis for drug abuse. J Forensic Sci 1989; 34: 1433–53.Google Scholar
Marques, PR, Tippetts, AS, Branch, DG. Cocaine in the hair of mother-infant pairs: quantitative analysis and correlations with urine measurements and self report. Am J Drug Alcohol Abuse 1993; 19: 159–75.Google Scholar

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