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  • Print publication year: 2016
  • Online publication date: April 2016

Chapter 2 - Alcohol as a drug

from Part I - Background to understanding

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Agarwal, D. P., & Goedde, H. W. (1990). Alcohol metabolism, alcohol intolerance, and alcoholism: Biochemical and pharmacogenetic approaches. Berlin: Springer.
Ball, D., Pembrey, M., & Stevens, D. N. (2007). Genomics. In Nutt, D., Robbins, T. W., Stimson, G. V., Ince, M., & Jackson, A. (Eds.), Drugs and the future (pp. 89131). London: Academic Press.
Beck, A., Schlagenhauf, F., Wüstenberg, T., Hein, J., Kienast, T., Kahnt, T., Schmack, K., Hägele, C., Knutson, B., Heinz, A., & Wrase, J. (2009). Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics. Biological Psychiatry, 66(8), 734742.
Birley, A. J., James, M. R., Dickson, P. A., Montgomery, G. W., Heath, A. C., Whitfield, J. B., & Martin, N. G. (2008). Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism. Human Molecular Genetics, 17(2), 179189.
Brick, J. (2004). Characteristics of alcohol: Chemistry, use, and abuse. In Brick, J. (Ed.), Handbook of the medical consequences of alcohol (pp. 16). New York: Haworth.
Butelman, E. R., Yuferov, V., & Kreek, M. J. (2012). κ-Opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction. Trends Neurosciences, 35(10), 587596.
Chen, C. H., Ferreira, J. C., Gross, E. R., & Mochly-Rosen, D. (2014). Targeting aldehyde dehydrogenase 2: New therapeutic opportunities. Physiological Reviews, 94(1), 134.
Edwards, G., & Gross, M. M. (1976). Alcohol dependence: Provisional description of a clinical syndrome. British Medical Journal, 1(6017), 10581061.
Erritzoe, D., Tziortzi, A., Bargiela, D., Colasanti, A., Searle, G. E., Gunn, R. N., … Lingford-Hughes, A. (2014). In vivo imaging of cerebral dopamine D3 receptors in alcoholism. Neuropsychopharmacology, 39(7), 17031712.
Fleming, M., Mihic, S. J., & Harris, R. A. (2006). Ethanol. In Brunton, L. L., Lazo, J., & Parker, K. L. (Eds.), Goodman and Gilman’s: The pharmacological basis of therapeutics (11th ed., pp. 591606). New York: McGraw Hill.
Heinz, A., Reimold, M., Wrase, J., Hermann, D., Croissant, B., Mundle, G., … Mann, K. (2005). Correlation of stable elevations in striatal μ-opioid receptor availability in detoxified alcoholic patients with alcohol craving: A positron emission tomography study using carbon 11-labeled carfentanil. Archives of General Psychiatry, 62(1), 5764.
Hermann, D., Weber-Fahr, W., Sartorius, A., Hoerst, M., Frischknecht, U., Tunc-Skarka, N., … Sommer, W.H. (2012). Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biological Psychiatry, 71(11), 10151021.
Holmes, A., Spanagel, R., & Krystal, J. H. (2013). Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl), 229(3), 539554.
Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014). Factors modulating neural reactivity to drug cues in addiction: A survey of human neuroimaging studies. Neuroscience & Biobehavioral Reviews, 38, 116.
Jelski, W., Chrostek, L., Szmitkowski, M., & Laszewicz, W. (2002). Activity of class I, II, III, and IV alcohol dehydrogenase isoenzymes in human gastric mucosa. Digestive Diseases and Sciences, 47(7), 15541557.
Krystal, J. H., Staley, J., Mason, G., Petrakis, I. L., Kaufman, J., Harris, R.A., … Lappalainen, J. (2006). Gamma-aminobutyric acid type A receptors and alcoholism: Intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry, 63(9), 957968.
Kumar, S., Porcu, P., Werner, D. F., Matthews, D. B., Diaz-Granados, J. L., Helfand, R. S., & Morrow, A. L. (2009). The role of GABA(A) receptors in the acute and chronic effects of ethanol: A decade of progress. Psychopharmacology (Berl), 205(4), 529564.
Lingford-Hughes, A., Watson, B., Kalk, N., & Reid, A. (2010). Neuropharmacology of addiction and how it informs treatment. British Medical Bulletin, 96, 93110.
Lingford-Hughes, A. R., Welch, S., Peters, L., & Nutt, D. J. (2012). BAP updated guidelines: Evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: Recommendations from BAP. Journal of Psychopharmacology, 26(7), 899952.
Lingford-Hughes, A. R., Wilson, S. J., Cunningham, V. J., Feeney, A., Stevensen, B., Brooks, D. J., & Nutt, D. (2005). GABA-benzodiazepine receptor function in alcohol dependence: A combined 11C-flumazenil PET and pharmacodynamic study. Psychopharmacology, 180, 595606.
Martinez, D., & Narendran, R. (2010). Imaging neurotransmitter release by drugs of abuse. Current Topics in Behavioral Neurosciences, 3, 219245.
Mutschler, J., Abbruzzese, E., Witt, S. H., Dirican, G., Nieratschker, V., Frank, J., … Kiefer, F. (2012). Functional polymorphism of the dopamine β-hydroxylase gene is associated with increased risk of disulfiram-induced adverse effects in alcohol-dependent patients. Journal of Clinical Psychopharmacology, 32(4), 578580.
Monnig, M. A., Tonigan, J. S., Yeo, R. A., Thoma, R. J., & McCrady, B. S. (2013). White matter volume in alcohol use disorders: A meta-analysis. Addiction Biology, 18(3), 581592.
Nutt, D. (1999). Alcohol and the brain. Pharmacological insights for psychiatrists. British Journal of Psychiatry, 175, 114119.
Nutt, D., Lingford-Hughes, A., Erritzoe, D., & Stokes, P. R. (2015). The dopamine theory of addiction: 40 years of highs and lows. Nature Reviews Neuroscience, 16, 305–132.
Ramchandani, V. A., Umhau, J., Pavon, F. J., Ruiz-Velasco, V., Margas, W., Sun, H., … Heilig, M. (2011). A genetic determinant of the striatal dopamine response to alcohol in men. Molecular Psychiatry, 16(8):809817.
Rudolph, U., & Knoflach, F. (2011). Beyond classical benzodiazepines: Novel therapeutic potential of GABAA receptor subtypes. Nature Reviews Drug Discovery, 10(9), 685697.
Schacht, J. P., Anton, R. F., & Myrick, H. (2013). Functional neuroimaging studies of alcohol cue reactivity: A quantitative meta-analysis and systematic review. Addiction Biology, 18(1), 121133.
Sullivan, E. V., & Pfefferbaum, A. (2005). Neurocircuitry in alcoholism: A substrate of disruption and repair. Psychopharmacology, 180, 583594.
Tyacke, R. J., Lingford-Hughes, A., Reed, L. J., & Nutt, D. J. (2010). GABAB receptors in addiction and its treatment. Advances Pharmacology, 58, 373396.
van Holst, R. J., Clark, L., Veltman, D. J., van den Brink, W., & Goudriaan, A.E. (2014). Enhanced striatal responses during expectancy coding in alcohol dependence. Drug and Alcohol Dependence, 142, 204208.
Walker, B. M., & Koob, G. F. (2008). Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology, 33(3), 643652.
Ward, R. J., Lallemand, F., & de Witte, P. (2009). Biochemical and neurotransmitter changes implicated in alcohol-induced brain damage in chronic or “binge drinking” alcohol abuse. Alcohol and Alcoholism, 44(2), 128135.