Skip to main content Accessibility help
×
Hostname: page-component-7c8c6479df-24hb2 Total loading time: 0 Render date: 2024-03-28T08:01:25.508Z Has data issue: false hasContentIssue false

Ch 2 - Method

Published online by Cambridge University Press:  05 August 2016

Get access

Summary

SOURCE OF DATA

The Oxford Regional Health Authority

The Department of Medical Genetics, located in the Churchill Hospital, Oxford, provides a service for the four counties (population 2-52 million) forming the administrative area of the Oxford Regional Health Authority under the National Health Service (Fig. 1). Out-patient clinics provide genetic consultant services in all the NHS general hospitals which together cover the Region, to which general practitioners and consultants in other specialties refer cases. Kindred or family members living outside the Oxford Region may be served by other regional departments, according to where they reside, which, for genetic investigations, will require exchange of information between consultants of different Regions. It is sometimes convenient to agree that one Region should deal with families divided between two or more Regions. Not all Regional Genetic Departments have the resources in staff and experience to maintain a DNA laboratory capable of carrying out presymptomatic linkage analyses in Huntington's chorea and patients will then be referred to the most conveniently situated department of a neighbouring Region. The Oxford Regional Department of Medical Genetics had assembled resources and gained considerable expertise in linkage analysis for some years before the advent of a presymptomatic linkage test in Huntington's chorea.

Subjects

Our subjects were the affected and unaffected members of families with Huntington's chorea who were interested in the presymptomatic linkage test for the gene for Huntington's chorea and living within Oxford Regional Health Authority. In 1985-6 a letter was sent to all families who had previously been referred to and seen by the Medical Genetics Department of the Churchill Hospital, Oxford, for Huntington's chorea, offering an interview to explain the test. To this number was added new referrals for Huntington's chorea from 1985 to 1990.

Families of subjects referred to the Department of Medical Genetics were interviewed either in their homes or at hospital out-patient departments by a psychiatrist and a community nursing sister attached to the department.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Method
  • David C. Watt
  • Book: A Clinico-Genetic Study of Psychiatric Disorder in Huntington's Chorea
  • Online publication: 05 August 2016
  • Chapter DOI: https://doi.org/10.1017/CBO9780511752681.003
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Method
  • David C. Watt
  • Book: A Clinico-Genetic Study of Psychiatric Disorder in Huntington's Chorea
  • Online publication: 05 August 2016
  • Chapter DOI: https://doi.org/10.1017/CBO9780511752681.003
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Method
  • David C. Watt
  • Book: A Clinico-Genetic Study of Psychiatric Disorder in Huntington's Chorea
  • Online publication: 05 August 2016
  • Chapter DOI: https://doi.org/10.1017/CBO9780511752681.003
Available formats
×