Book contents
- Frontmatter
- Contents
- Preface
- Contributors
- Part I Clinical Syndromes – General
- Part II Clinical Syndromes – Head and Neck
- Part III Clinical Syndromes – Eye
- Part IV Clinical Syndromes – Skin and Lymph Nodes
- Part V Clinical Syndromes – Respiratory Tract
- Part VI Clinical Syndromes – Heart and Blood Vessels
- Part VII Clinical Syndromes – Gastrointestinal Tract, Liver, and Abdomen
- Part VIII Clinical Syndromes – Genitourinary Tract
- Part IX Clinical Syndromes – Musculoskeletal System
- Part X Clinical Syndromes – Neurologic System
- Part XI The Susceptible Host
- Part XII HIV
- Part XIII Nosocomial Infection
- Part XIV Infections Related to Surgery and Trauma
- Part XV Prevention of Infection
- 111 Nonsurgical Antimicrobial Prophylaxis
- 112 Surgical Prophylaxis
- 113 Immunizations
- Part XVI Travel and Recreation
- Part XVII Bioterrorism
- Part XVIII Specific Organisms – Bacteria
- Part XIX Specific Organisms – Spirochetes
- Part XX Specific Organisms – Mycoplasma and Chlamydia
- Part XXI Specific Organisms – Rickettsia, Ehrlichia, and Anaplasma
- Part XXII Specific Organisms – Fungi
- Part XXIII Specific Organisms – Viruses
- Part XXIV Specific Organisms – Parasites
- Part XXV Antimicrobial Therapy – General Considerations
- Index
111 - Nonsurgical Antimicrobial Prophylaxis
from Part XV - Prevention of Infection
Published online by Cambridge University Press: 05 March 2013
- Frontmatter
- Contents
- Preface
- Contributors
- Part I Clinical Syndromes – General
- Part II Clinical Syndromes – Head and Neck
- Part III Clinical Syndromes – Eye
- Part IV Clinical Syndromes – Skin and Lymph Nodes
- Part V Clinical Syndromes – Respiratory Tract
- Part VI Clinical Syndromes – Heart and Blood Vessels
- Part VII Clinical Syndromes – Gastrointestinal Tract, Liver, and Abdomen
- Part VIII Clinical Syndromes – Genitourinary Tract
- Part IX Clinical Syndromes – Musculoskeletal System
- Part X Clinical Syndromes – Neurologic System
- Part XI The Susceptible Host
- Part XII HIV
- Part XIII Nosocomial Infection
- Part XIV Infections Related to Surgery and Trauma
- Part XV Prevention of Infection
- 111 Nonsurgical Antimicrobial Prophylaxis
- 112 Surgical Prophylaxis
- 113 Immunizations
- Part XVI Travel and Recreation
- Part XVII Bioterrorism
- Part XVIII Specific Organisms – Bacteria
- Part XIX Specific Organisms – Spirochetes
- Part XX Specific Organisms – Mycoplasma and Chlamydia
- Part XXI Specific Organisms – Rickettsia, Ehrlichia, and Anaplasma
- Part XXII Specific Organisms – Fungi
- Part XXIII Specific Organisms – Viruses
- Part XXIV Specific Organisms – Parasites
- Part XXV Antimicrobial Therapy – General Considerations
- Index
Summary
PREVENTION
Chemoprophylaxis is the use of an antimicrobial agent to prevent infection. Chemoprophylaxis is often administered after exposure to a virulent pathogen or before a procedure associated with risk of infection. Chronic chemoprophylaxis is sometimes administered to persons with underlying conditions that predispose to recurrent or severe infection. Antibiotics can also be used to prevent clinical disease in persons infected with a microorganism such as Mycobacterium tuberculosis. This strategy has been called secondary prophylaxis but is now referred to as pre-emptive therapy. Immunization, another excellent means of preventing infection, is discussed in Chapter 113, Immunizations. This chapter discusses the specific areas where antimicrobial prophylaxis is generally accepted. For information on prophylaxis of bacterial endocarditis, see Chapter 36, Endocarditis of Natural and Prosthetic Valves: Treatment and Prophylaxis; for information on prophylaxis in persons infected with the human immunodeficiency virus (HIV), see Chapter 100, Prophylaxis of Opportunistic Infections in HIV Disease; for malaria prophylaxis, see Chapter 198, Malaria: Treatment and Prophylaxis; for prophylaxis related to transplant recipients and neutropenic patients, see Chapter 87, Infections in Transplant Patients, and Chapter 84, Infections in the Neutropenic Patient; and for surgical prophylaxis, see Chapter 112, Surgical Prophylaxis.
Several concepts are important in determining whether chemoprophylaxis is appropriate for a particular situation. In general, prophylaxis is recommended when the risk of infection is high or the consequences significant.
- Type
- Chapter
- Information
- Clinical Infectious Disease , pp. 791 - 796Publisher: Cambridge University PressPrint publication year: 2008