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Section I - Iatrogenic ischemic strokes: peri- and postoperative strokes

Published online by Cambridge University Press:  20 October 2016

Alexander Tsiskaridze
Affiliation:
Sarajishvili Institute of Neurology, Tblisi State University, Georgia
Arne Lindgren
Affiliation:
Department of Neurology, University Hospital Lund, Sweden
Adnan I. Qureshi
Affiliation:
Department of Neurology, University of Minnesota
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Treatment-Related Stroke
Including Iatrogenic and In-Hospital Strokes
, pp. 1 - 62
Publisher: Cambridge University Press
Print publication year: 2016

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References

References

Hart, R, Hindman, B. Mechanisms of perioperative cerebral infarction. Stroke. 1982; 13:766–73.
Larsen, S F, Zaric, D, Bosen, G. Postoperative cerebrovascular accidents in general surgery. Stroke. Acta Anaesthesiol Scand. 1988; 32:698701.
Parikh, S, Cohen, J R. Postoperative stroke after general surgical procedures. NY State J Med. 1993; 93:162–5.
Limburg, M, Wijdicks, E F, Li, H. Ischemic stroke after surgical procedures: Clinical features, neuroimaging, and stroke factors. Neurology. 1998; 50:895901.
Kikura, M, Oikawa, F, Yamamoto, K, et al. Myocardial infarction and cerebrovascular accident following non-cardiac surgery: Differences in postoperative temporal distribution and risk factors. J Thromb Haemost. 2008; 6:742–8.
Nosan, D K, Gomez, C R, Maves, M D. Perioperative stroke in patients undergoing head and neck surgery. Ann Otol Rhonol Laryngol. 1993; 102:717–23.
Bateman, B T, Schumacher, H C, Wang, S, Shaefi, S, Berman, M F. Perioperative acute ischemic stroke in non-cardiac and non-vascular surgery: Incidence, risk factors, and outcomes. Anesthesiology. 2009; 110:231–8.
Polanczyk, C A, Marcantonio, E, Goldman, L, et al. Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med. 2001; 134(8):637–43.
Reich, D L, Bennett-Guerrero, E, Bodian, C A, et al. Intraoperative tachycardia and hypertension are independently associated with adverse outcome in noncardiac surgery of long duration. Anesth Analg. 2002; 95(2):273–7.
Brooks, D C, Schindler, J L. Perioperative stroke: Risk assessment, prevention and treatment. Current Treatment Options in Cardiovascular Medicine. 2014; 16:282.
Press, M J, Chassin, M R, Wang, J, Tuhrim, S, Halm, E A. Predicting medical and surgical complications of carotid endarterectomy: comparing the risk indexes. Arch Intern Med. 2006; 166(8):914–20.
Lee, T H, Marcantonio, E R, Mangione, C M, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999; 100(10):1043–9.
van Diepen, S, Youngson, E, Ezekowitz, J A, McAlister, F A. Which risk score best predicts perioperative outcomes in nonvalvular atrial fibrillation patients undergoing noncardiac surgery?Am Heart J. 2014; 168(1):60–7.
Bijker, J B, Persoon, S, Peelen, L M, et al. Anesthesiology. 2012; 116(3):658–64.
Ng, J L, Chan, M T, Gelb, A W. Perioperative stroke in noncardiac, nonneurosurgical surgery. Anesthesiology. 2011; 115(4):879–90.
Hinterhuber, G, Böhler, K, Kittler, H, Quehenberger, P. Dermatol Surg. 2006; 32(5):632–9.
Broderick, J P, Bonomo, J B, Kissela, B M, et al. Withdrawal of antithrombotic agents and its impact on ischemic stroke occurrence. Stroke. 2011; 42(9):2509–14.
Sedlaczek, O, Caplan, L, Hennerici, M. Impaired washout-embolism and ischemic stroke: further examples and proof of concept. Cerebrovasc Dis. 2005; 19(6):396401.
Kim, J S, Ko, S B, Shin, H E, Han, S R, Lee, K S. Perioperative stroke in the brain and spinal cord following an induced hypotension. Yonsei Med J. 2003; 44(1):143–5.
Langmayr, J J, Ortler, M, Obwegeser, A, Felber, S. Quadriplegia after lumbar disc surgery. A case report. Spine. 1996; 21(16):1932–5.
Jorgensen, M E, Torp-Pedersen, C, Gislason, G H, et al. Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery. JAMA. 2014; 312(3):269277.
Biteker, M, Dayan, A, Can, M M, et al. Impaired fasting glucose is associated with increased perioperative cardiovascular event rates in patients undergoing major non-cardiothoracic surgery. Cardiovasc Diabetol. 2011; 10:63.
Gentile, N T, Seftchick, M W, Huynh, T, Kruus, L K, Gaughan, J. Decreased mortality by normalizing blood glucose after acute ischemic stroke. Acad Emerg Med. 2006; 13(2):174–80.
Douketis, J D, Spyropoulos, A C, Kaatz, S, et al. Perioperative bridging anticoagulation in patients with atrial fibrillation. New England Journal of Medicine. 2015; 373(9):823–33.
Steinberg, B A, Peterson, E D, Kim, S, et al. Use and outcomes associated with bridging during anticoagulation interruptions in patients with atrial fibrillation: Findings from the outcomes registry for better informed treatment of atrial fibrillation (ORBIT-AF). Circulation. 2015; 131(5):488–94.
Gialdini, G, Nearing, K, Bhave, P D, et al. Perioperative atrial fibrillation and the long-term risk of ischemic stroke. JAMA. 2014; 312(6):616–22.
Epstein, A E, Alexander, J C, Gutterman, D D, Maisel, W, Wharton, J M, American College of Chest Physicians. Anticoagulation: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest. 2005; 128(2 Suppl):24S27S.
Frendl, G, Sodickson, A C, Chung, M K, et al. AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. J Thorac Cardiovasc Surg. 2014; 148(3):e153–93.
Maulaz, A B, Bezerra, D C, Michel, P, Bogousslavsky, J. Effect of discontinuing aspirin therapy on the risk of brain ischemic stroke. Arch Neurol. 2005; 62(8):1217–20.
Genewein, U, Haeberli, A, Straub, P W, Beer, J H. Rebound after cessation of oral anticoagulant therapy: the biochemical evidence. Br J Haematol. 1996; 92(2):479–85.
Douketis, J D, Spyropoulos, A C, Spencer, F A, et al.; American College of Chest Physicians. Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; Feb;141(2 Suppl):e326S–50S. Erratum in: Chest. 2012; 141(4):1129.
Assia, E I, Raskin, T, Kaiserman, I, Rotenstreich, Y, Segev, F. Effect of aspirin intake on bleeding during cataract surgery. J Cataract Refract Surg. 1998; 24(9):1243–6.
Giannarini, G, Mogorovich, A, Valent, F, et al. Continuing or discontinuing low-dose aspirin before transrectal prostate biopsy: results of a prospective randomized trial. Urology. 2007; 70(3):501–5.
Kovich, O, Otley, C C. Thrombotic complications related to discontinuation of warfarin and aspirin therapy perioperatively for cutaneous operation. J Am Acad Dermatol. 2003; 48(2):233–7.
Bajkin, B V, Bajkin, I A, Petrovic, B B. The effects of combined oral anticoagulant-aspirin therapy in patients undergoing tooth extractions: a prospective study. J Am Dent Assoc. 2012; 143(7):771–6.
Ferraris, V A, Swanson, E. Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. Surg Gynecol Obstet. 1983; 156(4):439–42.
Capodanno, D, Musumeci, G, Lettieri, C, et al. Impact of bridging with perioperative low-molecular-weight heparin on cardiac and bleeding outcomes of stented patients undergoing non-cardiac surgery. Thromb Haemost. 2015; 114(2):423–31.
Armstrong, M J, Schneck, M J, Biller, J. Discontinuation of perioperative antiplatelet and anticoagulant therapy in stroke patients. Neurol Clin. 2006; 24(4):607–30.
Yusuf, S, Zhao, F, Mehta, S R, et al. Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001; 345(7):494502. Erratum in: N Engl J Med 2001; 345(23):1716.
Larson, B J, Zumberg, M S, Kitchens, C S. A feasibility study of continuing dose-reduced warfarin for invasive procedures in patients with high thromboembolic risk. Chest. 2005; 127(3):922–7.
Dunn, A S, Turpie, A G. Perioperative management of patients receiving oral anticoagulants: a systematic review. Arch Intern Med. 2003; 163:901–8.
The American Society for Gastrointestinal Endoscopy. Guideline: Management of antithrombotic agents for endoscopic procedures. 2009; doi:10.1016/j.gie.2009.09.040. www.asge.org/uploadedFiles/Publications_and_Products/Practice_Guidelines/PIIS0016510709025498.pdf.
POISE Study Group, Devereaux, P J, Yang, H, Yusuf, S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008; 371(9627):1839–47.
Wong, G Y, Warner, D O, Schroeder, D R, et al. Risk of surgery and anesthesia for ischemic stroke. Anesthesiology. 2000; 92:425–32.
Stentella, P, Frega, A, Cipriano, L, et al. Prevention of thromboembolic complications in women undergoing gynecologic surgery. Clin Exp Obstet Gynecol. 1997; 24:5860.
Celebi, F, Balik, A A, Yildirgan, M I, et al. Thromboembolic prophylaxis after major abdominal surgery. Ulus Travma Derg. 2001; 7:44–8.
Amarigiri, S V, Lees, T A. Elastic compression stockings for prevention of deep vein thrombosis. Cochrane Database Syst Rev. 2000; CD001484.
Chalela, J A, Katzan, I, Liebeskind, D S, et al. Safety of intra-arterial thrombolysis in the postoperative period. Stroke. 2001; 32(6):1365–9.

References

CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet. 1996; 348(9038):1329–39.
Sigvant, B, Wiberg-Hedman, K, Bergqvist, D, et al. A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischemia and sex differences. J Vasc Surg. 2007; 45(6):1185–91.
Steg, P G, Bhatt, D L, Wilson, P W, et al. One-year cardiovascular event rates in outpatients with atherothrombosis. JAMA. 2007; 297(11):1197–206.
Diehm, C, Allenberg, J R, Pittrow, D, et al. Mortality and vascular morbidity in older adults with asymptomatic versus symptomatic peripheral artery disease. Circulation. 2009; 120(21):2053–61.
Clark, C E, Taylor, R S, Shore, A C, Ukoumunne, O C, Campbell, J L. Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis. Lancet. 2012; 379(9819):905–14.
Naylor, A R, Bown, M J. Stroke after cardiac surgery and its association with asymptomatic carotid disease: an updated systematic review and meta-analysis. Eur J Vasc Endovasc Surg. 2011; 41(5):607–24.
Ballotta, E, Renon, L, Da Giau, G, et al. Prospective randomized study on asymptomatic severe carotid stenosis and perioperative stroke risk in patients undergoing major vascular surgery: prophylactic or deferred carotid endarterectomy? Ann Vasc Surg. 2005; 19(6):876–81.
Bergqvist, D, Rosén, M. Health technology assessment in surgery. Scand J Surg. 2012; 101(2):132–7.
Patel, H J, Nguyen, C, Diener, A C, et al. Open arch reconstruction in the endovascular era: analysis of 721 patients over 17 years. J Thorac Cardiovasc Surg. 2011; 141(6):1417–23.
Sundt, T M 3rd, Orszulak, T A, Cook, D J, Schaff, H V. Improving results of open arch replacement. Ann Thorac Surg. 2008; 86(3):787–96.
Schermerhorn, M L, Giles, K A, Hamdan, A D, et al. Population-based outcomes of open descending thoracic aortic aneurysm repair. J Vasc Surg. 2008; 48(4):821–7.
Nakamura, K, Nakamura, E, Yano, M, et al. Factors influencing permanent neurologic dysfunction and mortality after total arch replacement with separate arch vessel grafting using selective cerebral perfusion. Ann Thorac Cardiovasc Surg. 2011; 17(1):3944.
Cheng, G, Zhang, L. [Adverse events related to bevacizumab and the management principles in non-small cell lung cancer]. Zhongguo Fei Ai Za Zhi. 2010; 13(6):563–7.
Gupta, P K, Pipinos, I I, Miller, W J, et al. A population-based study of risk factors for stroke after carotid endarterectomy using the ACS NSQIP database. J Surg Res. 2011; 167(2):182–91.
Parlani, G, De Rango, P, Cieri, E, et al. Diabetes is not a predictor of outcome for carotid revascularization with stenting as it may be for carotid endarterectomy. J Vasc Surg. 2012; 55(1):7989.
Rothwell, P M, Slattery, J, Warlow, C P. A systematic comparison of the risks of stroke and death due to carotid endarterectomy for symptomatic and asymptomatic stenosis. Stroke. 1996; 27(2):266–9.
Naylor, A R, Rothwell, P M, Bell, P R. Overview of the principal results and secondary analyses from the European and North American randomised trials of endarterectomy for symptomatic carotid stenosis. Eur J Vasc Endovasc Surg. 2003; 26(2):115–29.
Antonopoulos, C N, Kakisis, J D, Sergentanis, T N, Liapis, C D. Eversion versus conventional carotid endarterectomy: a meta-analysis of randomised and non-randomised studies. Eur J Vasc Endovasc Surg. 2011; 42(6):751–65.
Economopoulos, K P, Sergentanis, T N, Tsivgoulis, G, Mariolis, A D, Stefanadis, C. Carotid artery stenting versus carotid endarterectomy: a comprehensive meta-analysis of short-term and long-term outcomes. Stroke. 2011; 42(3):687–92.
Usman, A A, Tang, G L, Eskandari, M K. Metaanalysis of procedural stroke and death among octogenarians: carotid stenting versus carotid endarterectomy. J Am Coll Surg. 2009; 208(6):1124–31.
Stromberg, S, Gelin, J, Osterberg, T, et al. Very urgent carotid endarterectomy confers increased procedural risk. Stroke. 2012; 43(5):1331–5.
Adriaensen, M E, Bosch, J L, Halpern, E F, Myriam Hunink, M G, Gazelle, G S. Elective endovascular versus open surgical repair of abdominal aortic aneurysms: systematic review of short-term results. Radiology. 2002; 224(3):739–47.
Blankensteijn, J D. Mortality and morbidity rates after conventional abdominal aortic aneurysm repair. Semin Interv Cardiol. 2000; 5(1):713.
Schermerhorn, M L, O’Malley, A J, Jhaveri, A, et al. Endovascular vs. open repair of abdominal aortic aneurysms in the Medicare population. N Engl J Med. 2008; 358(5):464–74.
Kikura, M, Takada, T, Sato, S. Preexisting morbidity as an independent risk factor for perioperative acute thromboembolism syndrome. Arch Surg. 2005; 140(12):1210–7.
Ng, J L, Chan, M T, Gelb, A W. Perioperative stroke in noncardiac, nonneurosurgical surgery. Anesthesiology. 2011; 115(4):879–90.
Bijker, J B, Persoon, S, Peelen, L M, et al. Intraoperative hypotension and perioperative ischemic stroke after general surgery: a nested case-control study. Anesthesiology. 2012; 116(3):658–64.
Parikh, S, Cohen, J R. Perioperative stroke after general surgical procedures. N Y State J Med. 1993; 93(3):162–5.
Larsen, S F, Zaric, D, Boysen, G. Postoperative cerebrovascular accidents in general surgery. Acta Anaesthesiol Scand. 1988; 32(8):698701.
Limburg, M, Wijdicks, E F, Li, H. Ischemic stroke after surgical procedures: clinical features, neuroimaging, and risk factors. Neurology. 1998; 50(4):895901.
Sobel, M, Verhaeghe, R. Antithrombotic therapy for peripheral artery occlusive disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008; 133(6 Suppl):815S-43S.
Lindblad, B, Persson, N H, Takolander, R, Bergqvist, D. Does low-dose acetylsalicylic acid prevent stroke after carotid surgery? A double-blind, placebo-controlled randomized trial. Stroke. 1993; 24(8):1125–8.
Sharpe, R Y, Dennis, M J, Nasim, A, et al. Dual antiplatelet therapy prior to carotid endarterectomy reduces post-operative embolisation and thromboembolic events: post-operative transcranial Doppler monitoring is now unnecessary. Eur J Vasc Endovasc Surg. 2010; 40(2):162–7.
Payne, D A, Jones, C I, Hayes, P D, et al. Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy. Circulation. 2004; 109(12):1476–81.
O’Neil-Callahan, K, Katsimaglis, G, Tepper, M R, et al. Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) study. J Am Coll Cardiol. 2005; 45(3):336–42.
Durazzo, A E, Machado, F S, Ikeoka, D T, et al. Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial. J Vasc Surg. 2004; 39(5):967–75.
Sillesen, H, Amarenco, P, Hennerici, M G, et al. Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2008; 39(12):3297–302.
Kennedy, J, Quan, H, Buchan, A M, Ghali, W A, Feasby, T E. Statins are associated with better outcomes after carotid endarterectomy in symptomatic patients. Stroke. 2005; 36(10):2072–6.
McGirt, M J, Perler, B A, Brooke, B S, et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors reduce the risk of perioperative stroke and mortality after carotid endarterectomy. J Vasc Surg. 2005; 42(5):829–36.
Sharpe, R, Sayers, R D, McCarthy, M J, et al. The war against error: a 15 year experience of completion angioscopy following carotid endarterectomy. Eur J Vasc Endovasc Surg. 2012; 43(2):139–45.
Rockman, C B, Halm, E A. Intraoperative imaging: does it really improve perioperative outcomes of carotid endarterectomy? Semin Vasc Surg. 2007; 20(4):236–43.
Wallaert, J B, Goodney, P P, Vignati, J J, et al. Completion imaging after carotid endarterectomy in the Vascular Study Group of New England. J Vasc Surg. 2011; 54(2):376–85, 85 e13.
Bond, R, Rerkasem, K, Rothwell, P M. Systematic review of the risks of carotid endarterectomy in relation to the clinical indication for and timing of surgery. Stroke. 2003; 34(9):2290–301.
Turnipseed, W D, Berkoff, H A, Belzer, F O. Postoperative stroke in cardiac and peripheral vascular disease. Ann Surg. 1980; 192(3):365–8.
Liapis, C D, Bell, P R, Mikhailidis, D, Sivenius, J, et al. ESVS guidelines. Invasive treatment for carotid stenosis: indications, techniques. Eur J Vasc Endovasc Surg. 2009; 37(4 Suppl):119.
Plate, G, Hollier, L H, O’Brien, P C, Pairolero, P C, Cherry, K J. Late cerebrovascular accidents after repair of abdominal aortic aneurysms. Acta Chir Scand. 1988; 154(1):25–9.
Harris, E J Jr., Moneta, G L, Yeager, R A, Taylor, L M Jr., Porter, J M. Neurologic deficits following noncarotid vascular surgery. Am J Surg. 1992; 163(5):537–40.
Pomposelli, F B, Kansal, N, Hamdan, A D, et al. A decade of experience with dorsalis pedis artery bypass: analysis of outcome in more than 1000 cases. J Vasc Surg. 2003; 37(2):307–15.
Liapis, C D, Kakisis, J D, Dimitroulis, D A, et al. Carotid ultrasound findings as a predictor of long-term survival after abdominal aortic aneurysm repair: a 14-year prospective study. J Vasc Surg. 2003; 38(6):1220–5.
Blankensteijn, J D, de Jong, S E, Prinssen, M, et al. Two-year outcomes after conventional or endovascular repair of abdominal aortic aneurysms. N Engl J Med. 2005; 352(23):2398–405.
Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial. Lancet. 2005; 365(9478):2179–86.
Jensen, L P, Lepantalo, M, Fossdal, J E, et al. Dacron or PTFE for above-knee femoropopliteal bypass. a multicenter randomised study. Eur J Vasc Endovasc Surg. 2007; 34(1):44–9.
Biancari, F, Salenius, J P, Heikkinen, M, et al. Risk-scoring method for prediction of 30-day postoperative outcome after infrainguinal surgical revascularization for critical lower-limb ischemia: a Finnvasc registry study. World J Surg. 2007; 31(1):217–25.
Cherr, GS, Wang, J, Zimmerman, P M, Dosluoglu, H H. Depression is associated with worse patency and recurrent leg symptoms after lower extremity revascularization. J Vasc Surg. 2007; 45(4):744–50.
Lederle, F A, Freischlag, J A, Kyriakides, T C, et al. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA. 2009; 302(14):1535–42.
Lange, C P, Ploeg, A J, Lardenoye, J W, Breslau, P J. Patient- and procedure-specific risk factors for postoperative complications in peripheral vascular surgery. Qual Saf Health Care. 2009; 18(2):131–6.
Gisbertz, S S, Ramzan, M, Tutein Nolthenius, R P, et al. Short-term results of a randomized trial comparing remote endarterectomy and supragenicular bypass surgery for long occlusions of the superficial femoral artery [the REVAS trial]. Eur J Vasc Endovasc Surg. 2009; 37(1):6876.
Brown, L C, Thompson, S G, Greenhalgh, R M, Powell, J T. Incidence of cardiovascular events and death after open or endovascular repair of abdominal aortic aneurysm in the randomized EVAR trial 1. Br J Surg. 2011; 98(7):935–42.
Becquemin, J P, Pillet, J C, Lescalie, F, et al. A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low- to moderate-risk patients. J Vasc Surg. 2011; 53(5):1167–73 e1.
Svensson, L G, Crawford, E S, Hess, K R, Coselli, J S, Safi, H J. Variables predictive of outcome in 832 patients undergoing repairs of the descending thoracic aorta. Chest. 1993; 104(4):1248–53.
Borst, H G, Jurmann, M, Buhner, B, Laas, J. Risk of replacement of descending aorta with a standardized left heart bypass technique. J Thorac Cardiovasc Surg. 1994; 107(1):126–32.
Kouchoukos, N T, Masetti, P, Rokkas, C K, Murphy, S F, Blackstone, E H. Safety and efficacy of hypothermic cardiopulmonary bypass and circulatory arrest for operations on the descending thoracic and thoracoabdominal aorta. Ann Thorac Surg. 2001; 72(3):699707.
Brandt, M, Hussel, K, Walluscheck, K P, et al. Stent-graft repair versus open surgery for the descending aorta: a case-control study. J Endovasc Ther. 2004; 11(5):535–8.
Coselli, J S, LeMaire, S A, Conklin, L D, Adams, G J. Left heart bypass during descending thoracic aortic aneurysm repair does not reduce the incidence of paraplegia. Ann Thorac Surg. 2004; 77(4):1298–303.
Estrera, A L, Miller, C C 3rd, Chen, E P, et al. Descending thoracic aortic aneurysm repair: 12-year experience using distal aortic perfusion and cerebrospinal fluid drainage. Ann Thorac Surg. 2005; 80(4):1290–6.
Stone, D H, Brewster, D C, Kwolek, C J, et al. Stent-graft versus open-surgical repair of the thoracic aorta: mid-term results. J Vasc Surg. 2006; 44(6):1188–97.
Khaladj, N, Shrestha, M, Meck, S, et al. Hypothermic circulatory arrest with selective antegrade cerebral perfusion in ascending aortic and aortic arch surgery: a risk factor analysis for adverse outcome in 501 patients. J Thorac Cardiovasc Surg. 2008; 135(4):908–14.
Kulik, A, Castner, C F, Kouchoukos, N T. Outcomes after thoracoabdominal aortic aneurysm repair with hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 2011; 141(4):953–60.
Thomas, M, Li, Z, Cook, D J, Greason, K L, Sundt, T M. Contemporary results of open aortic arch surgery. J Thorac Cardiovasc Surg. 2012; 144(4):838–44.
Kragsterman, B, Logason, K, Ahari, A, et al. Risk factors for complications after carotid endarterectomy: a population-based study. Eur J Vasc Endovasc Surg. 2004; 28(1):98103.
Halliday, A, Mansfield, A, Marro, J, et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet. 2004; 363(9420):1491–502.
Brott, T G, Hobson, R W, 2nd, Howard, G, et al. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010; 363(1):1123.
Halliday, A, Harrison, M, Hayter, E, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet. 2010; 376(9746):1074–84.

References

Walker, A E, Robins, M, Weinfeld, F D. The National Survey of Stroke: Clinical findings. Stroke. 1981; 12:1344.
Kalfas, I H, Little, J R. Postoperative hemorrhage: a survey of 4992 intracranial procedures. Neurosurgery. 1988; 23: 343–7.
Palmer, J D, Sparrow, O C, Iannotti, F I. Postoperative hematoma: A 5-year survey and identification of avoidable risk factors. Neurosurgery. 1994; 35: 1061–5.
MacMahon, S, Rodgers, A. Blood pressure, antihypertensive treatment and stroke risk. J Hypertens Suppl. 1994; 12: S514.
Cohen, Y C, Djulbegovic, B, Shamai-Lubovitz, O, Mozes, B. The bleeding risk and natural history of idiopathic thrombocytopenic purpura in patients with persistent low platelet counts. Arch Intern Med. 2000; 160: 1630–8.
Biller, J, Feinberg, W M, Castaldo, JE, et al. Guidelines for carotid endarterectomy: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Circulation. 1998; 97: 501–9.
Feinberg, W M, Albers, G W, Barnett, HJ, et al. Guidelines for the management of transient ischemic attacks. From the Ad Hoc Committee on Guidelines for the Management of Transient Ischemic Attacks of the Stroke Council of the American Heart Association. Circulation. 1994; 89: 2950–65.
Korinth, M C. Low-dose aspirin before intracranial surgery – results of a survey among neurosurgeons in Germany. Acta Neurochir. 2006; 148: 1189–96.
Benveniste, R, Germano, I M. Evaluation of factors predicting accurate resections of high-grade gliomas by using frameless image-guided stereotactic guidance. Neurosurgical Focus. 2003; 14: e5.
Martin, A, Rojas, S, Chamorro, A, et al. Why does acute hyperglycemia worsen the outcome for transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation. Stroke. 2006; 37: 1288–95.
Nadig, A S, King, A T. Traumatic extradural haematoma revealed after contralateral decompressive craniectomy. Br J Neurosurg. 2012. www.ncbi.nlm.nih.gov/pubmed/22762248
Sturiale, C L, De Bonis, P, Rigante, L, et al. Do traumatic brain contusions increase in size after decompressive craniectomy? J Neurotrauma. 2012; 29: 2723–26.
Walcott, B P, Nahed, B V, Sheth, S A, et al. Bilateral hemicraniectomy in non-penetrating traumatic brain injury. J Neurotrauma. 2012; 29: 1879–85.
Winn, H R, Richardson, A E, Jane, JA. The long-term prognosis in untreated cerebral aneurysm: A 10-year evaluation of 364 patients. Ann Neurolog. 1977; 1: 358–70.
Voldby, B, Enevoldsen, E M. Intracranial pressure changes following aneurysm rupture. Part 3: Recurrent hemorrhage. J Neurosurg. 1982; 56: 784–9.
Connolly, E S Jr, Kader, A A, Frazzini, V I, Winfree, C, Solomon, R A. The safety of intraoperative lumbar drainage for acutely ruptured intracranial aneurysm: Technical note. Surg Neurol. 1997; 48: 338–44.
Rosenorn, J, Westergaard, L, Hansen, P H. Mannitol induced rebleeding from intracranial aneurysm: Case report. J Neurosurg. 1983; 59: 529–30.
Graf, C J, Nibbelink, D W. Randomized treatment study: Intracranial surgery. In Sahs, A L and Nibbelink, D W, eds. Aneurysm Subarachnoid Hemorrhage: Report of the Cooperative Study. Baltimore: Urban and Schwarzenburg. 1981; 145202.
Schramm, J, Cedzich, C. Outcome and management of intraoperative aneurysm rupture. Surg Neurol. 1993; 40: 2630.
Ondra, S L, Troupp, H, George, E D, Schwab, K. The natural history of symptomatic arteriovenous malformations of the brain: A 24-year follow-up assessment. J Neurosurg. 1990; 73: 387–91.
Kondziolka, D, McLaughlin, M R, Kestle, J R W. Simple risk predictors for arteriovenous malformations hemorrhage. Neurosurgery. 1995; 37: 851–5.
Baijim van Beijnum, J, van der Worp, H B, Buis, D R, et al. Treatment of brain arteriovenous malformations: a systematic review and meta-analysis. JAMA. 2011; 306: 2011–19.
Spetzler, R F, Wilson, C B, Weinstein, P, et al. Normal perfusion pressure breakthrough theory. Clin Neurosurg. 1978; 25: 651–72.
al-Rodhan, N R, Sundt, T M, Piepgras, D G, et al. Occlusive hyperemia: A theory of the hemodynamic complications following resection of intracerebral arteriovenous malformations. J Neurosurg. 1993; 78: 167–75.
Landriel Ibañez, F A, Hem, S, Ajler, P, et al. A new classification of complications in neurosurgery. World Neurosurg. 2011; 75: 709–15.

References

Rosengart, A J, Schultheiss, K E, Tolentino, J, Macdonald, R L. Prognostic factors for outcome in patients with aneurysmal subarachnoid hemorrhage. Stroke. 2007; 38: 2315–21.
Rabinstein, A A, Weigand, S, Atkinson, J L, Wijdicks, E F. Patterns of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke. 2005; 36: 992–7.
Nornes, H. The role of intracranial pressure in the arrest of hemorrhage in patients with ruptured intracranial aneurysm. J Neurosurg. 1973; 39: 226–34.
Dreier, J P, Ebert, N, Priller, J, et al. Products of hemolysis in the subarachnoid space inducing spreading ischemia in the cortex and focal necrosis in rats: A model for delayed ischemic neurological deficits after subarachnoid hemorrhage? J Neurosurg. 2000; 93: 658–66.
Ostrowski, R P, Colohan, A R, Zhang, J H. Molecular mechanisms of early brain injury after subarachnoid hemorrhage. Neurol Res. 2006; 28: 399414.
Vergouwen, M D, Vermeulen, M, van Gijn, J, et al. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: Proposal of a multidisciplinary research group. Stroke. 2010; 41: 2391–5.
Schmidt, J M, Wartenberg, K E, Fernandez, A, et al. Frequency and clinical impact of asymptomatic cerebral infarction due to vasospasm after subarachnoid hemorrhage. J Neurosurg. 2008; 109: 1052–9.
Baldwin, M E, Macdonald, R L, Dezheng, H, et al. Early vasospasm on admission angiography in patients with aneurysmal subarachnoid haemorrhage is a predictor for in-hospital complications and poor outcome. Stroke. 2004; 35: 2506–11.
Cahill, J, Calvert, J W, Zhang, J H. Mechanisms of early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2006; 26: 1341–53.
Pluta, R M. Delayed cerebral vasospasm and nitric oxide: Review, new hypothesis, and proposed treatment. Pharmacol Ther. 2005; 105: 2356.
Seifert, V, Loffler, B M, Zimmermann, M, Roux, S, Stolke, D. Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma. J Neurosurg. 1995; 82: 5562.
Sehba, F A, Bederson, J B. Mechanisms of acute brain injury after subarachnoid hemorrhage. Neurol Res. 2006; 28: 381–98.
Turner, C P, Bergeron, M, Matz, P, et al. Heme oxygenase-1 is induced in glia throughout brain by subarachnoid hemoglobin. J Cereb Blood Flow Metab. 1998; 18: 257–73.
Dietrich, H H, Dacey, R G Jr. Molecular keys to the problems of cerebral vasospasm. Neurosurgery. 2000; 46: 517–30.
Nishizawa, S, Laher, I. Signaling mechanisms in cerebral vasospasm. Trends Cardiovasc Med. 2005; 15: 2434.
Zimmermann, M, Seifert, V. Endothelin and subarachnoid hemorrhage: An overview. Neurosurgery. 1998; 43: 863–75.
Fassbender, K, Hodapp, B, Rossol, S, et al. Endothelin-1 in subarachnoid hemorrhage: An acute-phase reactant produced by cerebrospinal fluid leukocytes. Stroke. 2000; 31: 2971–5.
Macdonald, R L, Higashida, R T, Keller, E, et al. Randomized trial of clazosentan in patients with aneurysmal subarachnoid hemorrhage undergoing endovascular coiling. Stroke. 2012; 43: 1463–9.
Luders, J C, Weihl, C C, Lin, G, et al. Adenoviral gene transfer of nitric oxide synthase increases cerebral blood flow in rats. Neurosurgery. 2000; 47: 1206–14.
Clatterbuck, R E, Gailloud, P, Tierney, T, et al. Release of a nitric oxide donor for the prevention of delayed cerebral vasospasm following experimental subarachnoid hemorrhage in nonhuman primates. J Neurosurg. 2005; 103: 745–51.
Tierney, T S, Pradilla, G, Wang, P P, Clatterbuck, R E, Tamargo, R J. Intracranial delivery of the nitric oxide donor diethylenetriamine/nitric oxide from a controlled-release polymer: Toxicity in cynomolgus monkeys. Neurosurgery. 2006; 58: 952–60.
Pluta, R M, Dejam, A, Grimes, G, Gladwin, M T, Oldfield, E H. Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. JAMA. 2005; 293: 1477–84.
McGirt, M J, Lynch, J R, Parra, A, et al. Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage. Stroke. 2002; 33: 2950–6.
McGirt, M J, Pradilla, G, Legnani, F G, et al. Systemic administration of simvastatin after the onset of experimental subarachnoid hemorrhage attenuates cerebral vasospasm. Neurosurgery. 2006; 58: 945–51.
Tseng, M Y, Czosnyka, M, Richards, H, Pickard, J D, Kirkpatrick, P J. Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: A phase II randomized placebo-controlled trial. Stroke. 2005; 36: 1627–32.
Dreier, J P, Korner, K, Ebert, N, et al. Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by n-nitro-l-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space. J Cereb Blood Flow Metab. 1998; 18: 978–90.
Ishiguro, M, Wellman, T L, Honda, A, et al. Emergence of a R-type Ca2+ channel (CAV 2.3) contributes to cerebral artery constriction after subarachnoid hemorrhage. Circ Res. 2005; 96: 419–26.
Pluta, R M, Hansen-Schwartz, J, Dreier, J, et al. Cerebral vasospasm following subarachnoid hemorrhage: Time for a new world of thought. Neurol Res. 2009; 31: 151–8.
Kusaka, G, Ishikawa, M, Nanda, A, Granger, D N, Zhang, J H. Signaling pathways for early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2004; 24: 916–25.
Birse, S H, Tom, M I. Incidence of cerebral infarction associated with ruptured intracranial aneurysms. A study of 8 unoperated cases of anterior cerebral aneurysm. Neurology. 1960; 10: 101–6.
Dreier, J P, Woitzik, J, Fabricius, M, et al. Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations. Brain. 2006; 129: 3224–37.
Stein, S C, Levine, J M, Nagpal, S, LeRoux, P D. Vasospasm as the sole cause of cerebral ischemia: how strong is the evidence? Neurosurg Focus. 2006; 21: E2.
Park, S, Yamaguchi, M, Zhou, Z, et al. Neurovascular protection reduces early brain injury after subarachnoid hemorrhage. Stroke. 2004; 35: 2412–17.
Fisher, C M, Kistler, J P, Davis, J M. Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery, 1980; 6: 19.
Kistler, J P, Crowell, R M, Davis, K R. The relation of cerebral vasospasm to the extent and location of subarachnoid blood visualized by CT scan: A prospective study. Neurology, 1983; 33: 424–36.
Claassen, J, Bernardini, G L, Kreiter, K et al. Effect of cisternal and ventricular blood on risk of delayed cerebral ischemia after subarachnoid hemorrhage: The Fisher scale revisited. Stroke. 2001; 32: 2012–20.
Connolly, E S Jr., Rabinstein, A, Carhuapoma, J R, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: A statement for healthcare professionals from a special writing group of the stroke council, American Heart Association. Stroke. 2012; 43: 1711–37.
Diringer, M N, Bleck, T P, Claude Hemphill, J 3rd, et al. Critical care management of patients following aneurysmal subarachnoid hemorrhage: Recommendations from the Neurocritical Care Society’s multidisciplinary consensus conference. Neurocrit Care. 2011; 15: 211–40.
Washington, C W, Zipfel, G J. Detection and monitoring of vasospasm and delayed cerebral ischemia: A review and assessment of the literature. Neurocrit Care. 2011; 15: 312–17.
Sloan, M A, Alexandrov, A V, Tegeler, C H, et al. Assessment: Transcranial Doppler ultrasonography: Report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology. Neurology. 2004; 62: 1468–81.
Harrigan, M R, Magnano, C R, Guterman, L R, Hopkins, L N. Computed tomographic perfusion in the management of aneurysmal subarachnoid hemorrhage: New application of an existent technique. Neurosurgery. 2005; 56: 304–17.
Greenberg, E D, Gold, R, Reichman, M, et al. Diagnostic accuracy of CT angiography and CT perfusion for cerebral vasospasm: A meta-analysis. Am J Neuroradiol. 2010; 31: 1853–60.
Stocchetti, N. Triggers for aggressive interventions in subarachnoid hemorrhage. Neurocrit Care. 2011; 15: 324–8.
Hanggi, D. Monitoring and detection of vasospasm II: EEG and invasive monitoring. Neurocrit Care. 2011; 15: 318–23.
Dorhout Mees, S M, Rinkel, G J, Feigin, V L, et al. Calcium antagonists for aneurysmal subarachnoid hemorrhage. Stroke. 2008; 39: 514–15.
Philippon, J, Grob, R, Dagreou, F, et al. Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine. Acta Neurochirurgica. 1986; 82: 110–14.
Treggiari, M M, Walder, B, Suter, P M, Romand, J A. Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhage. J Neurosurg. 2003; 98: 978–84.
Rinkel, G J, Feigin, V L, Algra, A, van Gijn, J. Circulatory volume expansion therapy for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2004; CD000483.
Hasan, D, Vermeulen, M, Wijdicks, E F, Hijdra, A, van Gijn, J. Effect of fluid intake and antihypertensive treatment on cerebral ischemia after subarachnoid hemorrhage. Stroke. 1989; 20: 1511–15.
Wong, G K, Poon, W S, Chan, M T, et al. Intravenous magnesium sulphate for aneurysmal subarachnoid hemorrhage (IMASH): A randomized, double-blinded, placebo-controlled, multicenter phase III trial. Stroke. 2010; 41: 921–6.
Dorhout Mees, S M, Algra, A, et al. Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): A randomised placebo-controlled trial. Lancet. 2012; 380: 44–9.
Tseng, M Y. Summary of evidence on immediate statins therapy following aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2011; 15: 298301.
Zwienenberg-Lee, M, Hartman, J, Rudisill, N, et al. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: Results of a phase II multicenter, randomized, clinical trial. Stroke. 2008; 39: 1759–65.
Diringer, M N, Axelrod, Y. Hemodynamic manipulation in the neuro-intensive care unit: Cerebral perfusion pressure therapy in head injury and hemodynamic augmentation for cerebral vasospasm. Curr Opin Crit Care. 2007; 13: 156–62.
Lee, K H, Lukovits, T, Friedman, J A. “Triple-H” therapy for cerebral vasospasm following subarachnoid hemorrhage. Neurocrit Care. 2006; 4: 6876.
Meyer, R, Deem, S, Yanez, N D, et al. Current practices of triple-H prophylaxis and therapy in patients with subarachnoid hemorrhage. Neurocrit Care. 2011; 14: 2436.
Platz, J, Guresir, E, Vatter, H, et al. Unsecured intracranial aneurysms and induced hypertension in cerebral vasospasm: Is induced hypertension safe? Neurocrit Care. 2011; 14: 168–75.
Le Roux, P D. Anemia and transfusion after subarachnoid hemorrhage. Neurocrit Care. 2011; 15: 342–53.
Naidech, A M, Shaibani, A, Garg, R K, et al. Prospective, randomized trial of higher goal hemoglobin after subarachnoid hemorrhage. Neurocrit Care. 2011; 13: 313–20.
Frontera, J A, Fernandez, A, Schmidt, J M, et al. Clinical response to hypertensive hypervolemic therapy and outcome after subarachnoid hemorrhage. Neurosurgery. 2010; 66: 3541.
Kimball, M M, Velat, G J, Hoh, B L. Critical care guidelines on the endovascular management of cerebral vasospasm. Neurocrit Care. 2011; 15: 336–41.
Stuart, R M, Helbok, R, Kurtz, P, et al. High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: Prolonged effects on hemodynamic parameters and brain metabolism. Neurosurgery. 2011; 68: 337–45.
Tejada, J G, Taylor, R A, Ugurel, M S, et al. Safety and feasibility of intra-arterial nicardipine for the treatment of subarachnoid hemorrhage-associated vasospasm: Initial clinical experience with high-dose infusions. Am J Neuroradiol. 2007; 28: 844–8.
Shankar, J J, dos Santos, M P, Deus-Silva, L, Lum, C. Angiographic evaluation of the effect of intra-arterial milrinone therapy in patients with vasospasm from aneurysmal subarachnoid hemorrhage. Neuroradiology. 2011; 53: 123–8.
Jestaedt, L, Pham, M, Bartsch, A J, et al. The impact of balloon angioplasty on the evolution of vasospasm-related infarction after aneurysmal subarachnoid hemorrhage. Neurosurgery. 2008; 62: 610–17.

References

Vera, R, Lago, A, Fuentes, B, et al. In-hospital stroke: a multi-centre prospective registry. European J Neurology. 2011; 18:170–6.
Nadav, L, Gur, A Y, Korczyn, A D, Bornstein, N M. Stroke in hospitalized patients: are there special factors? Cerebrovasc Dis. 2002; 13:127–31.
Farooq, M U, Reeves, M J, Gargano, J, et al. In-hospital stroke in a statewide stroke registry. Cerbrovasc Dis. 2008; 25:1220.
Blacker, D J. In-hospital stroke. Lancet Neurol. 2003; 2:741–6.
Budaj, A, Flasinska, K, Goer, J M, et al. Magnitude of and risk factors for in-hospital and postdischarge stroke in patients with acute coronary syndromes: Findings from a Global Registry of Acute Coronary Events. Circulation. 2005; 111:3242–7.
Mahaffey, K W, Granger, C B, Sloan, M A, et al for the GUSTO-1 Investigators. Risk factors for in-hospital nonhemorrhagic stroke in patients with acute myocardial infarction treated with thrombolysis. Circulation. 1998; 97:757–64.
Waldo, A L, Becker, R C, Tapson, V F, Colgan, K J for the NABOR steering committee. Hospitalized patients with atrial fibrillation and a high risk of stroke are not being provided with adequate anticoagulation. J Am Coll Cardiol. 2005; 46:1729–36.
Habib, G. Management of infective endocarditis. Heart. 2006; 92:124–30.
Adams, H P, del Zoppo, G, Alberts, M J, et al. Guidelines for the early management of adults with ischemic stroke. Stroke. 2007; 38:1655–711.
De Sliva, D A, Manzano, J J F, Chang, H M, Wong, M C. Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis. Neurology. 2011; 76:1838–40.
Sandset, E C, Bath, P M, Boysen, G, et al. The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double blind trial. Lancet. 2011; 377:741–50.
Beer, C, Blacker, D, Bynevelt, M, Hankey, G J, Puddey, I B. A randomised placebo controlled trial of early ischemic stroke with atorvastatin and irbesartan. Int J Stroke. 2012; 7:104–11.
Sontineni, S P, Moos, A N, Andukari, V G, Schima, S M, Esterbrooks, D. Effectiveness of thrombolytic in acute embolic stroke due to infective endocarditis. Stroke Res Treat. 2010; 2010:841797.
Dabeabneh, H, Hedna, VS, Ford, J, et al. Endovascular intervention for acute stroke due to infective endocarditis: a case report. Neurosurg Focus. 2012; 32:E1.
Diringer, M N, Skolnick, B E, Mayer, S A, et al. Thromboembolic events with recombinant factor VII in spontaneous intracerebral hemorrhage: results from the Factor Seven for Acute Hemorrhagic Stroke (FAST) trial. Stroke. 2010; 41:4853.
Phan, T G, Koh, M, Wijdicks, E F. Safety of discontinuation of anticoagulation in patients with intracranial hemorrhage at high thromboembolic risk. Arch Neurol. 2000; 57:1710–13.
Diener, H C, Bogousslavsky, J, Brass, L M, et al. Aspirin and Clopidogrel Compared with Clopidogrel Alone after Recent Ischaemic Stroke or Transient Ischaemic Attack in High-risk Patients (MATCH): Randomised, double-blind, placebo-controlled trial. Lancet. 2004; 364:331–7.
Bhatt, D L, Fox, K A, Hacke, W, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006; 354:1706–17.
Wang, Y, Wang, Y, Zhao, X, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013; 369:1119.
Fisher, M, Loscalzo, J. The perils of antithrombotic therapy and potential resolutions. Circulation. 2011; 123:232–5.
Petty, G W, Brown, R D, Whisnant, J P, et al. Ischemic stroke subtypes: a population–based study of functional outcome, survival and recurrence. Stroke. 2000; 31:1062–8.
Rothwell, P M, Eliasziw, M, Gutnikov, S A, Warlow, C P, Barnett, H J. Carotid Endarterectomy Trialists Collaboration. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet. 2004; 363:915–24.
Brott, T G, Hobson, R W 2nd, Howard, G, et al. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010; 363:1123.
Hill, M D, Shrive, F M, Kennedy, J, Feasby, T E, Ghali, W A. Simultaneous carotid endarterectomy and coronary artery bypass surgery in Canada. Neurology. 64:1435–7.
Naylor, A R, Mehta, Z, Rothwell, P M. A systematic review and meta-analysis of 30-day outcomes following staged carotid artery stenting and coronary bypass. Eur J Vasc Endovasc Surg. 2009; 37:379–84.
Blacker, D J, Flemming, K D, Link, M J, Brown, R D. The pre-operative cerebrovascular consultation: common cerebrovascular questions before general or cardiac surgery. Mayo Clin Proc. 2004; 79:223–9.
Tendera, M, Aboyans, V, Bartelink, M, et al. ESC Guidelines on the diagnosis and treatment of peripheral artery diseases. European Heart Journal. 2011; 32:2851–906.
Anstwurm, K, Borges, A C, Halle, E, et al. Timing the valve replacement in infective endocarditis involving the brain. J Neurol. 2004; 251:1220–6.
Eckman, M H, Rosand, J, Knudsen, K A, Singer, D E, Greenberg, S M. Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis. Stroke. 2003; 34:1710–16.
Paciaroni, M, Agnelli, G. Should oral anticoagulants be restarted after warfarin-associated cerebral haemorrhage in patients with atrial fibrillation? Thrombosis and Haemostasis. 2014; 111:1418.
Holmes, D R, Reddy, D Y, Turi, Z G, et al. Percutaneous closure of the left atrial appendix versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet. 2009; 374:534–42.
Connolly, S J, Ezekowitz, M D, Yusuf, S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009; 361:1139–51.
Granger, C B, Alexander, J H, McMurray, J J, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011; 365:981–92.
Patel, M R, Mahaffey, K W, Garg, J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011; 365:883–91.
Hankey, G J. Intracranial hemorrhage and novel anticoagulants for atrial fibrillation: What have we learned? Curr Cardiol Rep. 2014; 16:480.
Caress, J B, Cartwright, M S, Donofrio, P D, Peacock, J D. The clinical features of 16 cases of stroke associated with the administration of IVIG. Neurology. 2003; 60:1822–4.
Incecik, F, Herquner, M O, Altunbasak, S, Yildizdas, D. Reversible posterior encephalopathy syndrome due to intravenous immunoglobulin in a child with Guillain-Barre syndrome. J Paediatr Neurosci. 2011; 6:138–40.
Townsend, R R. Stroke in chronic kidney disease: prevention and management. Clin J Am Soc Nephrol. 2008; 33:S11S16.
Seliger, S L, Gillen, D L, Longstreth, W T, Kestenbaum, B. Stehman-Breen, C O. Elevated risk of stroke among patients with end-stage renal disease. Kidney International. 2003; 64:603–9.
Farhoudi, M, Azar, S A, Abdi, R. Brain hemodynamics in patients with end-stage renal disease between hemodialysis sessions. IJKD. 2012; 6:110–13.
Rothwell, P M. Does blood pressure variability modulate cardiovascular risk? Curr Hypertens Rep. 2011; 13:177–86.
Agrawal, V, Rai, B, Fellows, J, McCullough, P A. In-hospital outcomes with thrombolytic therapy in patients with renal dysfunction presenting with acute ischemic stroke. Nephrol Dial Transplant. 2010; 25:1150–7.
Tutuncu, S, Ziegler, A M, Scheitz, J F, et al. Severe renal impairment is associated with symptomatic intracerebral hemorrhage after thrombolysis for ischemic stroke. Stroke. 2013; 44:3217–19.
Palacio, S, Gonzales, N R, Sangha, N S, Birnbaum, L A, Hart, R G. Thrombolysis for acute stroke in hemodialysis: international survey of expert opinion. Clin J Am Soc Nephrol. 2006; 1:1357–9.
Bennett, W M. Should dialysis patients ever receive warfarin and for what reasons? Clin J Am Soc Nephrol. 2006; 1:1357–9.
Verheugt, F W, Granger, C B. Oral anticoagulants for stroke prevention in atrial fibrillation: Current status, special situations, and unmet needs. Lancet. 2015; 386:303–10.
Ng, K P, Edwards, N C, Lip, G Y, Townend, J N, Ferro, C J. Atrial fibrillation in CKD: Balancing the risks and benefits of anticoagulation. American Journal of Kidney Diseases. 2013; 62:615–32.
Kruger, T, Brandenburg, V, Schlieper, G, Marx, N, Floege, J. Sailing between scylla and charybdis: Oral long-term anticoagulation in dialysis patients. Nephrology, Dialysis, Transplantation. 2013; 28:534–41.
Camm, A J, Lip, G Y, De Caterina, R, et al. Focused update of the ESC guidelines for the management of atrial fibrillation: An update of the 2010 ESC guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J. 2012; 33:2719–47.
Bang, O Y, Seok, J M, Kim, S G, et al. Ischemic stroke and cancer: stroke severely impacts cancer patients, while cancer increases the number of strokes. J Clin Neurol. 2011; 7:53–9.
Schwarzbach, C J. Systemic thrombolysis in cancer patients: is it safe and effective? Cerebrovasc Dis. 2012; Supp 2:64.
Khorana, A A. Cancer and thrombosis: implications of published guidelines for clinical practice. Annals of Oncology. 2009; 20:1619–30.
Coplin, W M, Cochran, M S, Levine, S R, Crawford, S W. Stroke after bone marrow transplantation. Frequency, aetiology and outcome. Brain. 2001; 124:1043–51.
Finkelstein, J, Cha, E, Scharf, S. Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity. International Journal of COPD. 2009; 4:337–49.
Seok, H Y, Seo, W, Eun, M, et al. Transient increase in intrathoracic pressure as a contributing factor to cardioembolic stroke. J Clin Neurol. 2010; 6:212–15.
Tan, S, Humphrey, G, Miles, P. Stroke due to carotid artery dissection. Postgrad Med J. 1991; 67:588–9.
Harms, H, Prass, K, Meisel, C, et al. Preventive antibacterial therapy in acute ischemic stroke: A randomised controlled trial (PATHERIS). PLoS ONE. 2008; 3(5):e2158.
Ling, L, He, X, Zeng, J, Lian, G Z. In-hospital cerebrovascular complications following orthotopic liver transplantation: A retrospective study. BMC Neurology. 2008; 8:52.
Joshi, D, Dickel, T, Aga, R, Smith-Laing, G. Stroke in inflammatory bowel disease: A report of two cases and review of the literature. Thrombosis Journal. 2008; 6:2.
Moris, G. Inflammatory bowel disease: An increased risk factor for neurologic complications. World Journal of Gastroenterology. 2014; 20:1228–37.
Cognat, E, Crassard, I, Denier, C, Vahedi, K, Bousser, M G. Cerebral venous thrombosis in inflammatory bowel diseases: eight cases and literature review. Int J Stroke. 2011; 6:487–92.
Andersohn, F, Waring, M, Garbe, E. Risk of ischemic stroke in patients with Crohn’s disease: A population-based nested case-control study. Inflamm Bowel Dis. 2010; 16:1387–92.
Singh, S, Singh, H, Loftus, E V Jr., Pardi, D S. Risk of cerebrovascular accidents and ischemic heart disease in patients with inflammatory bowel disease: A systematic review and meta-analysis. Clinical Gastroenterology and Hepatology. 2014; 12:382–93.
Yamamoto, Y, Nishiyama, Y, Katsura, K, Yamazaki, M, Katayama, Y. Hepatic encephalopathy with reversible focal neurologic signs resembling acute stroke: case report. J Stroke Cerebrovasc Dis. 2011; 20:377–80.
Brosch, J R, Janicki, M J. Intra-arterial thrombolysis as an ideal treatment for inflammatory bowel disease related thromboembolic stroke: A case report and review. Int J Neurosci. 2012; 122:541–4.
Chen, H, Wang, C, Lee, H, et al. Short-term case fatality rate and associated factors among inpatients with diabetic ketoacidosis and hyperglycaemic hyperosmolar state: A hospital-based analysis over a 15 year period. Inter Med. 2010; 49:729–37.
Foster, J R, Morrison, G, Fraser, D D. Diabetic ketoacidosis-associated stroke in children. Stroke Research and Treatment. 2011; doi:10.4061/2011/219706.
Wahlgren, N, Ahmed, N, Eriksson, N, et al. Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomised controlled trials. Safe Implementation of Thrombolysis in Stroke Monitoring Study (SITS-MOST). Stroke. 2008; 39:3316–22.
Hacke, W, Kaste, M, Bluhmki, E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischaemic stroke. N Engl J Med. 2008; 359:1371–29.
Bellolio, M F, Gilmore, R M, Stead, L G. Insulin for glycaemic control in acute ischaemic stroke. Cochrane Database Syst Rev. 2011; 9:CD005346.
Hardie, K, Hankey, G J, Jamrozik, K, Broadhurst, R J, Anderson, C. Ten year survival after first-ever stroke in the Perth community stroke study. Stroke. 2003; 34:1842–6.
Douglas, I J, Smeeth, L. Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ. 2008; 337a1277, doi:10.1136/bmj.a1277.
Wang, S, Liknkletter, C, Dore, D, et al. Age, antipsychotics, and the risk of ischemic stroke in the veterans health administration. Stroke. 2012; 43:2831.
Lin, H C, Hsiao, F H, Pfeiffer, S, Hwang, Y T, Lee, H S. An increased risk of stroke among young schizophrenia patients. Schizophrenia Research. 2008; 101:234–41.
Pan, A, Okereke, O I, Sun, Q, et al. Depression and incident stroke in women. Stroke. 2011; 42:2770–5.
Chernyshev, O Y, Martin-Schild, S, Albright, KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia. Neurology. 2010; 74:1340–5.

References

Farooq, M U, Reeves, M J, Gargano, J, et al. In-hospital stroke in a statewide registry. Cerebrovasc Dis. 2008; 25:1220.
Blacker, D J, Wijdicks, E F. Clinical characteristics and mechanisms of stroke after polytrauma. Mayo Clin Proc. 2004; 79:630–5.
Cothren, C C, Moore, E E. Blunt cerebrovascular injuries. Clinics. 2005; 60:489–96.
Lucas, C, Moulin, T, Deplanque, D, Tatu, L, Chavot, D. Stroke patterns of internal carotid artery dissection in 40 patients. Stroke. 1998; 29:2646–8.
Mokri, B, Piepgras, D G, Houser, O W. Traumatic dissections of the extracranial internal carotid artery. J Neurosurg. 1988; 68:189–97.
Ringer, A J, Matern, E, Parikh, S, Levine, N B. Screening for blunt cerebrovascular injury: selection criteria for use of angiography. J Neurosurg. 2010; 112:1146–9.
Wang, A C, Charters, M A, Thawani, J P, et al. Evaluating the use and utility of noninvasive angiography in diagnosing traumatic blunt cerebrovascular injury. J Trauma Acute Care Surg. 2012; 72:1601–10.
Clancy, T V, Gary, M J, Covington, D L, Brinker, C C, Blackman, D. A statewide analysis of level I and II trauma centers for patients with major injuries. J Trauma. 2001; 51:346–51.
Corti, R, Alerci, M, Tosi, C, et al. Images in cardiovascular medicine. Cerebral arterial embolism from a protruding atheroma of the aortic arch after a nonpenetrating chest trauma. Circulation. 1999; 100:1009–10.
Dennis, M S, Lo, K M, McDowall, M, West, T. Fractures after stroke. Stroke. 2002; 33:728–34.
Jauch, E C, Saver, J L, Adams, H P, et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013; 44:870947.
Ahmad, N, Ward, E, Natarajan, I, Roffe, C. Intravenous stroke thrombolysis in the presence of traumatic bone fractures. Cerebrovasc Dis. 2012; Supp 2:83.
Cohen, J E, Gomori, J M, Grigoriadis, S, et al. Intra-arterial thrombolysis and stent placement for traumatic carotid dissection with subsequent stroke: A combined simultaneous endovascular approach. J Neurol Sciences. 2008; 269:172–5.
Sugrue, P A, Hage, Z A, Surdell, D L, et al. Basilar artery occlusion following C1 lateral mass fracture managed by mechanical and pharmacological thrombolysis. Neurocritical Care. 2009; 11:255–60.
Furlan, A J. Endovascular therapy for stroke: it’s about time. N Engl J Med. 2015; 45:35–8.
Powers, W J, Derdeyn, C P, Biller, J, et al. AHA/ASA focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment. Stroke. 2015; published before print June 29, 2015.
Stein, D M, Boswell, S, Sliker, C W, Lui, F Y, Scalea, T M. Blunt cerebrovascular injuries: does treatment always matter? J Trauma. 2009; 66:132–43.
Cothren, C C, Biffl, W L, Moore, E E, Kashuk, J L, Johnson, J L. Treatment for blunt cerebrovascular injuries: equivalence of anticoagulation and antiplatelet agents. Arch Surg. 2009; 144:685–90.
Callcut, R A, Hanseman, D J, Solan, P D, et al. Early treatment of blunt cerebrovascular injury with concomitant hemorrhagic neurological injury is safe and effective. J Trauma Acute Care Surg. 2012; 72:338–45.
Davis, J W, Holbrook, T L, Hoyt, D B, et al. Blunt carotid dissection: incidence, associated injuries, screening and treatment. J Trauma. 1990; 30:1514–17.
Anson, J, Cromwell, R M. Cervicocranial arterial dissection. Neurosurgery. 1991; 29:8996.
Wahl, W L, Brandt, M M, Thompson, B G, Taheri, P A, Greefield, L J. Antiplatelet therapy: an alternative to heparin for blunt carotid injury. J Trauma. 2002; 52:896901.
Cothren, C C, Moore, E E, Biffl, W L, et al. Anticoagulation is the gold standard therapy for blunt carotid injuries to reduce stroke rate. Arch Surg. 2004; 139:545–6.
DiCocco, J M, Fabian, T C, Emmett, K P, et al. Optimal outcomes for patients with blunt cerebrovascular injury (BCVI): tailoring treatment to the lesion. J Am Coll Surg. 2011; 212:547–9.
Cothren, C C, Moore, E E, Ray, C E, et al. Carotid artery stents for blunt cerebrovascular injury: risks exceed benefits. Arch Surg. 2005; 140:480–5.
International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both or neither among 19 435 patients with acute ischaemic stroke. Lancet. 1997; 349:1569–81.
Chen, Y H, Kang, J H, Lin, H C. Patients with traumatic brain injury. Population-based study suggests increased risk of stroke. Stroke. 2011; 42:2733–9.
Glenn, M B. Sudden cardiac death and stroke with use of antipsychotic medications: Implications for clinicians treating individuals with traumatic brain injury. J Head Trauma Rehabil. 2010; 25:6870.
Blacker, D J. NSAIDS and stroke risk. Med J Aust. 2011; 41:488.
Wu, J C, Chen, Y C, Liu, L, et al. Increased risk of stroke after spinal cord injury. Neurology. 2012; 78:1051–7.
Rothwell, P M. Does blood pressure variability modulate cardiovascular risk? Curr Hypertens Rep. 2011; 13:177–86.
Weinhardt, J, Jacobson, K. Stroke assessment in the perioperative patient. Orthop Nurs. 2012; 31:21–6.