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Chapter 15 - Surveillance and Prevention of Infections Associated with Vascular Catheters

from Section 3 - Major HAI Categories: Surveillance and Prevention

Published online by Cambridge University Press:  02 April 2018

Ebbing Lautenbach
Affiliation:
University of Pennsylvania School of Medicine
Preeti N. Malani
Affiliation:
University of Michigan, Ann Arbor
Keith F. Woeltje
Affiliation:
Washington University School of Medicine, St Louis
Jennifer H. Han
Affiliation:
University of Pennsylvania School of Medicine
Emily K. Shuman
Affiliation:
University of Michigan, Ann Arbor
Jonas Marschall
Affiliation:
Washington University School of Medicine, St Louis
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Print publication year: 2018

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References

Climo, M, Diekema, D, Warren, DK, et al. Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention. Infect Control Hosp Epidemiol. 2003;24(12):942945.Google Scholar
Pronovost, P, Needham, D, Berenholtz, S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):27252732.CrossRefGoogle ScholarPubMed
Raad, I, Hanna, H, Maki, D. Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lancet infectious diseases. 2007;7(10):645657.Google Scholar
Pittet, D, Tarara, D, Wenzel, RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA. 1994;271(20):15981601.Google Scholar
Soufir, L, Timsit, JF, Mahe, C, Carlet, J, Regnier, B, Chevret, S. Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study. Infect Control Hosp Epidemiol. 1999;20(6):396401.CrossRefGoogle ScholarPubMed
Digiovine, B, Chenoweth, C, Watts, C, Higgins, M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med. 1999;160(3):976981.CrossRefGoogle ScholarPubMed
Rello, J, Ochagavia, A, Sabanes, E, et al. Evaluation of outcome of intravenous catheter-related infections in critically ill patients. Am J Respir Crit Care Med. 2000;162(3 Pt 1):10271030.Google Scholar
Pelletier, SJ, Crabtree, TD, Gleason, TG, Pruett, TL, Sawyer, RG. Bacteremia associated with central venous catheter infection is not an independent predictor of outcomes. J Am Coll Surg. 2000;190(6):671680; discussion 80–81.CrossRefGoogle Scholar
Renaud, B, Brun-Buisson, C. Outcomes of primary and catheter-related bacteremia: a cohort and case-control study in critically ill patients. Am J Respir Crit Care Med. 2001;163(7):15841590.Google Scholar
Rosenthal, VD, Guzman, S, Migone, O, Crnich, CJ. The attributable cost, length of hospital stay, and mortality of central line–associated bloodstream infection in intensive care departments in Argentina: a prospective, matched analysis. Am J Infect Control. 2003;31(8):475480.Google Scholar
Blot, SI, Depuydt, P, Annemans, L, et al. Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections. Clin Infect Dis. 2005;41(11):15911508.Google Scholar
Stevens, V, Geiger, K, Concannon, C, Nelson, RE, Brown, J, Dumyati, G. Inpatient costs, mortality and 30-day re-admission in patients with central-line-associated bloodstream infections. Clin Microbiol Infect. 2014;20(5):O3180324.Google Scholar
Goudie, A, Dynan, L, Brady, PW, Rettiganti, M. Attributable cost and length of stay for central line-associated bloodstream infections. Pediatrics. 2014;133(6):e15251532.Google Scholar
Zingg, W, Cartier-Fassler, V, Walder, B. Central venous catheter-associated infections. Best Pract Res Clin Anaesthesiol. 2008;22(3):407421.Google Scholar
Vincent, JL, Bihari, DJ, Suter, PM, et al. The prevalence of nosocomial infection in intensive care units in Europe: results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA. 1995;274(8):639644.Google Scholar
Vincent, JL, Rello, J, Marshall, J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302(21):23232329.Google Scholar
Dudeck, MA, Edwards, JR, Allen-Bridson, K, et al. National Healthcare Safety Network report, data summary for 2013: device-associated Module. Am J Infect Control. 2015;43(3):206221.CrossRefGoogle ScholarPubMed
Coello, R, Charlett, A, Ward, V, et al. Device-related sources of bacteraemia in English hospitals: opportunities for the prevention of hospital-acquired bacteraemia. J Hosp Infect. 2003;53(1):4657.Google Scholar
Rosenthal, VD, Maki, DG, Salomao, R, et al. Device-associated nosocomial infections in 55 intensive care units of 8 developing countries. Ann Intern Med. 2006;145(8):582591.CrossRefGoogle ScholarPubMed
Rosenthal, VD, Maki, DG, Mehta, Y, et al. International Nosocomial Infection Control Consortium (INICC) report, data summary of 43 countries for 2007–2012: device-associated module. Am J Infect Control. 2014;42(9):942–56.Google Scholar
Mostert, JW, Kenny, GM, Murphy, GP. Safe placement of central venous catheter into internal jugular veins. Arch Surg. 1970;101(3):431432.Google Scholar
Peters, JL, Mehtar, S, Vallis, CJ, Kenning, BR. Central venous catheter design and maintenance complications. Br J Anaesth. 1979;51(8):805806.Google Scholar
Pottecher, T, Forrler, M, Picardat, P, Krause, D, Bellocq, JP, Otteni, JC. Thrombogenicity of central venous catheters: prospective study of polyethylene, silicone and polyurethane catheters with phlebography or post-mortem examination. Eur Journal Anaesthesiol. 1984;1(4):361365.Google ScholarPubMed
Haley, RW, Quade, D, Freeman, HE, Bennett, JV. The SENIC Project: Study on the efficacy of nosocomial infection control (SENIC Project), Summary of study design. Am J Epidemiol. 1980;111(5):472–85.CrossRefGoogle Scholar
O’Grady, NP, Alexander, M, Dellinger, EP, et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recommendations and Reports. 2002;51(RR-10):129.Google ScholarPubMed
Marschall, J, Mermel, LA, Fakih, M, et al. Strategies to prevent central line–associated bloodstream infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014;35 Suppl 2:S89S107.Google Scholar
Maki, DG, Kluger, DM, Crnich, CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clinic Pro. 2006;81(9):115911571.CrossRefGoogle ScholarPubMed
Al Raiy, B, Fakih, MG, Bryan-Nomides, N et al. Peripherally inserted central venous catheters in the acute care setting: a safe alternative to high-risk short-term central venous catheters. Am J Infect Control. 2010;38(2):149153.Google Scholar
Zingg, W, Pittet, D. Peripheral venous catheters: an under-evaluated problem. Int J Antimicrob Agents. 2009;34 Suppl 4:S38S42.Google Scholar
Parienti, JJ, Thirion, M, Megarbane, B, et al. Femoral vs. jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008;299(20):24132422.Google Scholar
Parienti, JJ, Mongardon, N, Megarbane, B, et al. Intravascular complications of central venous catheterization by insertion site. N Engl J Med. 2015;373(13):12201229.Google Scholar
Richet, H, Hubert, B, Nitemberg, G, et al. Prospective multicenter study of vascular-catheter-related complications and risk factors for positive central-catheter cultures in intensive care unit patients. J Clin Microbiol. 1990;28(11):25202525.Google Scholar
Goetz, AM, Wagener, MM, Miller, JM, Muder, RR. Risk of infection due to central venous catheters: effect of site of placement and catheter type. Infect Control Hosp Epidemiol. 1998;19(11):842845.Google Scholar
Merrer, J, De Jonghe, B, Golliot, F, et al. Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial. JAMA. 2001;286(6):700707.Google Scholar
Cobb, DK, High, KP, Sawyer, RG, et al. A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters. N Engl J Med. 1992;327(15):10621068.Google Scholar
Cook, D, Randolph, A, Kernerman, P, et al. Central venous catheter replacement strategies: a systematic review of the literature. Crit Care Med. 1997;25(8):14171424.CrossRefGoogle ScholarPubMed
Zurcher, M, Tramer, MR, Walder, B. Colonization and bloodstream infection with single- versus multi-lumen central venous catheters: a quantitative systematic review. Anesth Analg. 2004;99(1):177182.Google Scholar
Timsit, JF, Farkas, JC, Boyer, JM, et al. Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis. Chest. 1998;114(1):207213.Google Scholar
Abdelkefi, A, Ben Othman, T, Kammoun, L, et al. Prevention of central venous line-related thrombosis by continuous infusion of low-dose unfractionated heparin, in patients with haemato-oncological disease: a randomized controlled trial. Thromb Haemost. 2004;92(3):654661.Google Scholar
Abdelkefi, A, Achour, W, Ben Othman, T, et al. Use of heparin-coated central venous lines to prevent catheter-related bloodstream infection. J Support Oncol. 2007;5(6):273278.Google Scholar
Zingg, W, Posfay-Barbe, KM, Pfister, RE, Touveneau, S, Pittet, D. Individualized catheter surveillance among neonates: a prospective, 8-year, single-center experience. Infect Control Hosp Epidemiol. 2011;32(1):4249.Google Scholar
Opilla, MT, Kirby, DF, Edmond, MB. Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients. JPEN J Parenter Enteral Nutr. 2007;31(4):302305.Google Scholar
Chen, HS, Wang, FD, Lin, M, Lin, YC, Huang, LJ, Liu, CY. Risk factors for central venous catheter-related infections in general surgery. J Microbiol Immunol Infect = Wei mian yu gan ran za zhi. 2006;39(3):231236.Google Scholar
Heidegger, CP, Berger, MM, Graf, S, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet. 2013;381(9864):385393.CrossRefGoogle ScholarPubMed
Thibault, R, Makhlouf, AM, Kossovsky, MP, et al. Healthcare-associated infections are associated with insufficient dietary intake: an observational cross-sectional study. PloS one. 2015;10(4):e0123695.CrossRefGoogle ScholarPubMed
Zingg, W, Holmes, A, Dettenkofer, M, et al. Hospital organisation, management, and structure for prevention of health-care-associated infection: a systematic review and expert consensus. Lancet Infect Dis. 2015;15(2):212224.Google Scholar
Fridkin, SK, Pear, SM, Williamson, TH, Galgiani, JN, Jarvis, WR. The role of understaffing in central venous catheter-associated bloodstream infections. Infect Control Hosp Epidemiol. 1996;17(3):150158.Google ScholarPubMed
Virtanen, M, Kurvinen, T, Terho, K, et al. Work hours, work stress, and collaboration among ward staff in relation to risk of hospital-associated infection among patients. Med Care. 2009;47(3):310318.Google Scholar
Pittet, D, Simon, A, Hugonnet, S, Pessoa-Silva, CL, Sauvan, V, Perneger, TV. Hand hygiene among physicians: performance, beliefs, and perceptions. Ann Intern Med. 2004;141(1):18.CrossRefGoogle ScholarPubMed
Cimiotti, JP, Haas, J, Saiman, L, Larson, EL. Impact of staffing on bloodstream infections in the neonatal intensive care unit. Arch Pediatr Adolesc Med. 2006;160(8):832836.Google Scholar
Alonso-Echanove, J, Edwards, JR, Richards, MJ, et al. Effect of nurse staffing and antimicrobial-impregnated central venous catheters on the risk for bloodstream infections in intensive care units. Infect Control Hosp Epidemiol. 2003;24(12):916925.CrossRefGoogle ScholarPubMed
Robert, J, Fridkin, SK, Blumberg, HM, et al. The influence of the composition of the nursing staff on primary bloodstream infection rates in a surgical intensive care unit. Infect Control Hosp Epidemiol. 2000;21(1):1217.CrossRefGoogle Scholar
Elder, NC, Brungs, SM, Nagy, M, Kudel, I, Render, ML. Intensive care unit nurses’ perceptions of safety after a highly specific safety intervention. Qual Safety Health Care. 17(1):2530. 2008.CrossRefGoogle ScholarPubMed
Saint, S, Kowalski, CP, Banaszak-Holl, J, Forman, J, Damschroder, L, Krein, SL. The importance of leadership in preventing healthcare-associated infection: results of a multisite qualitative study. Infect Control Hosp Epidemiol. 2010;31(9):901907.Google Scholar
Sinuff, T, Cook, D, Giacomini, M, Heyland, D, Dodek, P. Facilitating clinician adherence to guidelines in the intensive care unit: a multicenter, qualitative study. Crit Care Med. 2007;35(9):20832089.CrossRefGoogle ScholarPubMed
Snyders, RE, Goris, AJ, Gase, KA, Leone, CL, Doherty, JA, Woeltje, KF. Increasing the reliability of fully automated surveillance for central line-associated bloodstream infections. Infect Control Hosp Epidemiol. 2015;36(12):13961400.CrossRefGoogle ScholarPubMed
Metzger, KE, Rucker, Y, Callaghan, M, et al. The burden of mucosal barrier injury laboratory-confirmed bloodstream infection among hematology, oncology, and stem cell transplant patients. Infect Control Hosp Epidemiol. 2015;36(2):119124.CrossRefGoogle ScholarPubMed
Safdar, N, Fine, JP, Maki, DG. Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection. Ann Intern Med. 2005;142(6):451466.Google Scholar
Siegman-Igra, Y, Anglim, AM, Shapiro, DE, Adal, KA, Strain, BA, Farr, BM. Diagnosis of vascular catheter-related bloodstream infection: a meta-analysis. J Clin Microbiol. 1997;35(4):928936.Google Scholar
Blot, F, Nitenberg, G, Chachaty, E, et al. Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures. Lancet. 1999;354(9184):10711077.Google Scholar
Woeltje, KF, Butler, AM, Goris, AJ, et al. Automated surveillance for central line-associated bloodstream infection in intensive care units. Infect Control Hosp Epidemiol. 2008;29(9):842846.Google Scholar
Hota, B, Lin, M, Doherty, JA, et al. Formulation of a model for automating infection surveillance: algorithmic detection of central-line associated bloodstream infection. J Am Med Informatics Assoc: JAMIA. 2010;17(1):4248.Google Scholar
Khouli, H, Jahnes, K, Shapiro, J, et al. Performance of medical residents in sterile techniques during central vein catheterization: randomized trial of efficacy of simulation-based training. Chest. 2011;139(1):8087.Google Scholar
Mimoz, O, Lucet, JC, Kerforne, T, et al. Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial. Lancet. 2015;386(10008):20692077.Google Scholar
Cartier, V, Haenny, A, Inan, C, Walder, B, Zingg, W. No association between ultrasound-guided insertion of central venous catheters and bloodstream infection: a prospective observational study. J Hosp Infect. 2014;87(2):103108.Google Scholar
Dumyati, G, Concannon, C, van Wijngaarden, E, et al. Sustained reduction of central line-associated bloodstream infections outside the intensive care unit with a multimodal intervention focusing on central line maintenance. Am J Infect Control. 2014;42(7):723730.CrossRefGoogle ScholarPubMed
Gueri, K, Wagner, J, Rains, K, Bessesen, M. Reduction in central line–associated bloodstream infections by implementation of a postinsertion care bundle. Am J Infect Control. 2010;38(6):430433.Google Scholar
Blot, K, Bergs, J, Vogelaers, D, Blot, S, Vandijck, D. Prevention of central line–associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysis. Clin Infect Dis. 2014;59(1):96105.Google Scholar
Apisarnthanarak, A, Thongphubeth, K, Yuekyen, C, Warren, DK, Fraser, VJ. Effectiveness of a catheter-associated bloodstream infection bundle in a Thai tertiary care center: a 3-year study. Am J Infect Control. 2010;38(6):449455.Google Scholar
Bion, J, Richardson, A, Hibbert, P, et al. “Matching Michigan”: a 2-year stepped interventional programme to minimise central venous catheter-blood stream infections in intensive care units in England. BMJ Qual Safety. 2013;22(2):110123.CrossRefGoogle ScholarPubMed
DePalo, VA, McNicoll, L, Cornell, M, Rocha, JM, Adams, L, Pronovost, PJ. The Rhode Island ICU collaborative: a model for reducing central line-associated bloodstream infection and ventilator-associated pneumonia statewide. Qual Saf Health Care. 2010;19(6):555561.Google Scholar
Eggimann, P, Harbarth, S, Constantin, MN, Touveneau, S, Chevrolet, JC, Pittet, D. Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care. Lancet. 2000;355(9218):1864–8.Google Scholar
Guerin, K, Wagner, J, Rains, K, Bessesen, M. Reduction in central line–associated bloodstream infections by implementation of a postinsertion care bundle. Am J Infect Control. 38(6):430–3. 2010.Google Scholar
Marra, AR, Cal, RG, Durao, MS, Correa, L, Guastelli, LR, Moura, DF Jr., et al. Impact of a program to prevent central line-associated bloodstream infection in the zero tolerance era. Am J Infect Control. 2010.CrossRefGoogle ScholarPubMed
Miller, MR, Griswold, M, Harris, JM, et al. Decreasing PICU catheter-associated bloodstream infections: NACHRI’s quality transformation efforts. Pediatrics. 125(2):206213. 2010.Google Scholar
Palomar, M, Alvarez-Lerma, F, Riera, A, et al. Impact of a national multimodal intervention to prevent catheter-related bloodstream infection in the ICU: the Spanish experience. Crit Care Med. 2013;41(10):23642372.Google Scholar
Peredo, R, Sabatier, C, Villagra, A, et al. Reduction in catheter-related bloodstream infections in critically ill patients through a multiple system intervention. Eur J Clin Microbiol Infect Dis. 2010;29(9):11731177.Google Scholar
Perez Parra, A, Cruz Menarguez, M, Perez Granda, MJ, Tomey, MJ, Padilla, B, Bouza, E. A simple educational intervention to decrease incidence of central line-associated bloodstream infection (CLABSI) in intensive care units with low baseline incidence of CLABSI. Infect Control Hosp Epidemiol. 2010;31(9):964967.Google Scholar
Schulman, J, Stricof, R, Stevens, TP, et al. Statewide NICU central-line-associated bloodstream infection rates decline after bundles and checklists. Pediatrics. 2011;127(3):436444.Google Scholar
Venkatram, S, Rachmale, S, Kanna, B. Study of device use adjusted rates in health care–associated infections after implementation of “bundles” in a closed-model medical intensive care unit. J Crit Care. 2010;25(1):174 e11e18.Google Scholar
Weber, DJ, Brown, VM, Sickbert-Bennett, EE, Rutala, WA. Sustained and prolonged reduction in central line-associated bloodstream infections as a result of multiple interventions. Infect Control Hosp Epidemiol. 2010;31(8):875877.Google Scholar
Zingg, W, Imhof, A, Maggiorini, M, Stocker, R, Keller, E, Ruef, C. Impact of a prevention strategy targeting hand hygiene and catheter care on the incidence of catheter-related bloodstream infections. Crit Care Med. 2009;37(7):21672173; quiz 80.Google Scholar
Zingg, W, Cartier, V, Inan, C, et al. Hospital-wide multidisciplinary, multimodal intervention programme to reduce central venous catheter–associated bloodstream infection. PLoS One. 2014;9(4):e93898.Google Scholar
Sherertz, RJ, Ely, EW, Westbrook, DM, et al. Education of physicians-in-training can decrease the risk for vascular catheter infection. Ann Intern Med. 2000;132(8):641648.Google Scholar
Barsuk, JH, Cohen, ER, Feinglass, J, McGaghie, WC, Wayne, DB. Use of simulation-based education to reduce catheter-related bloodstream infections. Arch Intern Med. 2009;169(15):14201423.Google Scholar
Evans, LV, Dodge, KL, Shah, TD, et al. Simulation training in central venous catheter insertion: improved performance in clinical practice. Acad Med. 2010;85(9):14621469.Google Scholar
Marra, AR, Guastelli, LR, de Araujo, CM, et al. Positive deviance: a new strategy for improving hand hygiene compliance. Infect Control Hosp Epidemiol. 2010;31(1):1220.Google Scholar
Joshi, SC, Diwan, V, Tamhankar, AJ, et al. Qualitative study on perceptions of hand hygiene among hospital staff in a rural teaching hospital in India. J Hosp Infect. 2012;80(4):340344.CrossRefGoogle Scholar
Turnberg, W, Daniell, W, Simpson, T, et al. Personal healthcare worker (HCW) and work-site characteristics that affect HCWs’ use of respiratory-infection control measures in ambulatory healthcare settings. Infect Control Hosp Epidemiol. 2009;30(1):4752.Google Scholar
Nicol, PW, Watkins, RE, Donovan, RJ, Wynaden, D, Cadwallader, H. The power of vivid experience in hand hygiene compliance. J Hosp Infect 72(1):3642. 2009.Google Scholar
Larson, EL, Quiros, D, Lin, SX. Dissemination of the CDC’s Hand Hygiene Guideline and impact on infection rates. Am J Infect Control. 2007;35(10):666675.Google Scholar
Raad, II, Hohn, DC, Gilbreath, BJ, et al. Prevention of central venous catheter–related infections by using maximal sterile barrier precautions during insertion. Infect Control Hosp Epidemiol. 1994;15(4 Pt 1):231238.CrossRefGoogle ScholarPubMed
Quiros, D, Lin, S, Larson, EL. Attitudes toward practice guidelines among intensive care unit personnel: a cross-sectional anonymous survey. Heart Lung. 36(4):287297. 2007:Aug.Google Scholar
Haustein, T, Gastmeier, P, Holmes, A, et al. Use of benchmarking and public reporting for infection control in four high-income countries. Lancet Infect Dis. 2011;11(6):471481.Google Scholar
Damschroder, LJ, Aron, DC, Keith, RE, Kirsh, SR, Alexander, JA, Lowery, JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:50.Google Scholar
Gurses, AP, Murphy, DJ, Martinez, EA, Berenholtz, SM, Pronovost, PJ. A practical tool to identify and eliminate barriers to compliance with evidence-based guidelines. Jt Comm J Qual Patient Saf. 2009;35(10):526532, 485.Google Scholar
Hansen, S, Schwab, F, Behnke, M, et al. National influences on catheter-associated bloodstream infection rates: practices among national surveillance networks participating in the European HELICS project. J Hosp Infect. 2009;71(1):6673.Google Scholar
Hockenhull, JC, Dwan, KM, Smith, GW, et al. The clinical effectiveness of central venous catheters treated with anti-infective agents in preventing catheter-related bloodstream infections: a systematic review. Crit Care Med. 2009;37(2):702–12.CrossRefGoogle ScholarPubMed
Walder, B, Pittet, D, Tramer, MR. Prevention of bloodstream infections with central venous catheters treated with anti-infective agents depends on catheter type and insertion time: evidence from a meta-analysis. Infect Control Hosp Epidemiol. 2002;23(12):748756.Google Scholar
Falagas, ME, Fragoulis, K, Bliziotis, IA, Chatzinikolaou, I. Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials. J Antimicrob Chemother. 2007;59(3):359369.CrossRefGoogle ScholarPubMed
Cherry-Bukowiec, JR, Denchev, K, Dickinson, S, et al. Prevention of catheter-related blood stream infection: back to basics? Surg Infect (Larchmt). 2011;12(1):2732.Google Scholar
Marschall, J, Mermel, LA, Classen, D, et al. Strategies to prevent central line–associated bloodstream infections in acute care hospitals. Infect Control Hosp Epidemiol. 2008;29 Suppl 1:S2230.Google Scholar
O’Grady, NP, Alexander, M, Burns, LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2011;39(4 Suppl 1):S1S34.Google Scholar
Timsit, JF, Schwebel, C, Bouadma, L, et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA. 2009;301(12):12311241.Google Scholar
Timsit, JF, Mimoz, O, Mourvillier, B, et al. Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults. Am J Respir Crit Care Med. 2012;186(12):12721278.Google Scholar
Ruschulte, H, Franke, M, Gastmeier, P, et al. Prevention of central venous catheter related infections with chlorhexidine gluconate impregnated wound dressings: a randomized controlled trial. Ann Hematol. 2009;88(3):267272.Google Scholar
Mermel, LA, Allon, M, Bouza, E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter–related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;49(1):145.Google Scholar
Sherertz, RJ, Boger, MS, Collins, CA, Mason, L, Raad, II. Comparative in vitro efficacies of various catheter lock solutions. Antimicrob Agents Chemother. 2006;50(5):1865868.CrossRefGoogle ScholarPubMed
Takla, TA, Zelenitsky, SA, Vercaigne, LM. Effectiveness of a 30% ethanol/4% trisodium citrate locking solution in preventing biofilm formation by organisms causing haemodialysis catheter-related infections. J Antimicrob Chemother. 2008;62(5):10241026.Google Scholar
Cober, MP, Kovacevich, DS, Teitelbaum, DH. Ethanol-lock therapy for the prevention of central venous access device infections in pediatric patients with intestinal failure. JPEN J Parenter Enteral Nutr. 2010;35(1):6773.Google Scholar
Jones, BA, Hull, MA, Richardson, DS, et al. Efficacy of ethanol locks in reducing central venous catheter infections in pediatric patients with intestinal failure. J Pediatr Surg. 2010;45(6):12871293.CrossRefGoogle ScholarPubMed
Mermel, LA, Alang, N. Adverse effects associated with ethanol catheter lock solutions: a systematic review. J Antimicrob Chemother. 2014;69(10):26112619.Google Scholar
Dillon, PW, Jones, GR, Bagnall-Reeb, HA, Buckley, JD, Wiener, ES, Haase, GM. Prophylactic urokinase in the management of long-term venous access devices in children: a Children’s Oncology Group study. J Clin Oncol. 2004;22(13):27182723.Google Scholar
Kalmanti, M, Germanakis, J, Stiakaki, E, et al. Prophylaxis with urokinase in pediatric oncology patients with central venous catheters. Pediatr Hematol Oncol. 2002;19(3):173179.Google Scholar
van Rooden, CJ, Schippers, EF, Guiot, HF, et al. Prevention of coagulase-negative staphylococcal central venous catheter–related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. J Clin Oncol. 2008;26(3):428433.Google Scholar
Maki, DG, Ash, SR, Winger, RK, Lavin, P. A novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial. Crit Care Med. 2011;39(4):613620.Google Scholar
Climo, MW, Sepkowitz, KA, Zuccotti, G, et al. The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crit Care Med. 2009;37(6):185818565.Google Scholar
Munoz-Price, LS, Hota, B, Stemer, A, Weinstein, RA. Prevention of bloodstream infections by use of daily chlorhexidine baths for patients at a long-term acute care hospital. Infect Control Hosp Epidemiol. 2009;30(11):10311035.Google Scholar
Climo, MW, Yokoe, DS, Warren, DK, et al. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med. 2013;368(6):533–42.CrossRefGoogle ScholarPubMed
Huang, SS, Septimus, E, Kleinman, K, et al. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013;368(24):2255–65.Google Scholar
Quach, C, Milstone, AM, Perpete, C, Bonenfant, M, Moore, DL, Perreault, T. Chlorhexidine bathing in a tertiary care neonatal intensive care unit: impact on central line–associated bloodstream infections. Infect Control Hosp Epidemiol. 2014;35(2):158163.CrossRefGoogle Scholar
Pittet, D, Hugonnet, S, Harbarth, S, et al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme.[Erratum appears in Lancet 2000 Dec 23–30;356(9248):2196]. Lancet. 2000;356(9238):1307–1312.Google Scholar
Darouiche, RO, Wall, MJ Jr., Itani, KM, et al. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. N Engl J Med. 2010;362(1):1826.CrossRefGoogle ScholarPubMed
Batra, R, Cooper, BS, Whiteley, C, Patel, AK, Wyncoll, D, Edgeworth, JD. Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unit. Clin Infect Dis. 2010;50(2):210217.Google Scholar
Karakitsos, D, Labropoulos, N, De Groot, E, et al. Real-time ultrasound-guided catheterisation of the internal jugular vein: a prospective comparison with the landmark technique in critical care patients. Crit Care. 2006;10(6):R162.Google Scholar
Zingg, W, Cartier, V, Walder, B. No association between ultrasound-guided insertion of central venous catheters and bloodstream infection: a prospective observational study. J Hosp Infect. 2015.Google Scholar

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