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Chapter 12 - Premature Ovarian Insufficiency

Published online by Cambridge University Press:  28 January 2023

Naomi S. Crouch
St Michael's Hospital, Bristol
Cara E. Williams
Liverpool Women's Hospital
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Premature Ovarian Insufficiency (POI) is defined by follicular depletion that occurs under the age of 40 and is characterised by a gradual fall of hormone production by the ovary, leading to amenorrhoea and infertility. The hallmark for diagnosis is raised follicular stimulating hormone (FSH) above 25 IU/L measured twice, at least 4 weeks apart.

Publisher: Cambridge University Press
Print publication year: 2023

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