Published online by Cambridge University Press: 15 September 2022
ART in women over 40 years of age is a fundamentally complex undertaking fraught with many challenges. This chapter carefully reviews the data for effective ovarian reserve assessment and preconception counseling. For women undergoing IVF, we discuss the evidence base for the different stimulation regimens and the multitude of adjunctive treatments proposed for poor responders. Finally, we discuss expected treatment success and when to consider stopping further IVF attempts with autologous oocytes.