Book contents
- Neuroscience for Neurosurgeons
- Neuroscience for Neurosurgeons
- Copyright page
- Contents
- Contributors
- Section 1 Basic and Computational Neuroscience
- Section 2 Clinical Neurosurgical Diseases
- Chapter 12 Glioma
- Chapter 13 Brain Metastases: Molecules to Medicine
- Chapter 14 Benign Adult Brain Tumors and Pediatric Brain Tumors
- Chapter 15 Biomechanics of the Spine
- Chapter 16 Degenerative Cervical Myelopathy
- Chapter 17 Spondylolisthesis
- Chapter 18 Radiculopathy
- Chapter 19 Spinal Tumors
- Chapter 20 Acute Spinal Cord Injury and Spinal Trauma
- Chapter 21 Traumatic Brain Injury
- Chapter 22 Vascular Neurosurgery
- Chapter 23 Pediatric Vascular Malformations
- Chapter 24 Craniofacial Neurosurgery
- Chapter 25 Hydrocephalus
- Chapter 26 Peripheral Nerve Injury Response Mechanisms
- Chapter 27 Clinical Peripheral Nerve Injury Models
- Chapter 28 The Neuroscience of Functional Neurosurgery
- Chapter 29 Neuroradiology: Focused Ultrasound in Neurosurgery
- Chapter 30 Magnetic Resonance Imaging in Neurosurgery
- Chapter 31 Brain Mapping
- Index
- References
Chapter 24 - Craniofacial Neurosurgery
from Section 2 - Clinical Neurosurgical Diseases
Published online by Cambridge University Press: 04 January 2024
- Neuroscience for Neurosurgeons
- Neuroscience for Neurosurgeons
- Copyright page
- Contents
- Contributors
- Section 1 Basic and Computational Neuroscience
- Section 2 Clinical Neurosurgical Diseases
- Chapter 12 Glioma
- Chapter 13 Brain Metastases: Molecules to Medicine
- Chapter 14 Benign Adult Brain Tumors and Pediatric Brain Tumors
- Chapter 15 Biomechanics of the Spine
- Chapter 16 Degenerative Cervical Myelopathy
- Chapter 17 Spondylolisthesis
- Chapter 18 Radiculopathy
- Chapter 19 Spinal Tumors
- Chapter 20 Acute Spinal Cord Injury and Spinal Trauma
- Chapter 21 Traumatic Brain Injury
- Chapter 22 Vascular Neurosurgery
- Chapter 23 Pediatric Vascular Malformations
- Chapter 24 Craniofacial Neurosurgery
- Chapter 25 Hydrocephalus
- Chapter 26 Peripheral Nerve Injury Response Mechanisms
- Chapter 27 Clinical Peripheral Nerve Injury Models
- Chapter 28 The Neuroscience of Functional Neurosurgery
- Chapter 29 Neuroradiology: Focused Ultrasound in Neurosurgery
- Chapter 30 Magnetic Resonance Imaging in Neurosurgery
- Chapter 31 Brain Mapping
- Index
- References
Summary
Craniosynostosis is a condition associated with the pathologic premature fusion of one or more cranial sutures. Physiologically, the metopic suture closes in infancy, while the remaining sutures close years later, even into adulthood. In craniosynostosis, characteristic calvarial deformity first appears on ultrasound in the second trimester and precedes identifiable suture fusion by 4–16 weeks. When this premature closure occurs, it is associated with restriction of calvarial growth perpendicular to the fused suture, with compensatory increase in growth at the remaining sutures. Previously there was debate as to whether the suture fusion itself drives this restriction of growth, or whether a cranial base deformity drives the abnormal development through tension bands in the dura. Currently there is a preponderance of evidence from human and rabbit studies supporting the idea that suture fusion is at least a significant contributor to the overall skull shape abnormality. The natural history of the disease is such that the deformity observed in infancy increases in severity if not surgically corrected.
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- Neuroscience for Neurosurgeons , pp. 326 - 334Publisher: Cambridge University PressPrint publication year: 2024