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Preface

Published online by Cambridge University Press:  04 August 2010

M. Flint Beal
Affiliation:
Cornell University, New York
Anthony E. Lang
Affiliation:
University of Toronto
Albert C. Ludolph
Affiliation:
Universität Ulm, Germany
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Summary

Neurodegenerative diseases are becoming increasingly prevalent with the aging of the general population. The twentieth century witnessed a significant demographic change in the human population of the industrialized world that is currently followed by a similar shift of life expectancy to upper age ranges in Asia, Africa, and Middle and South America. Quality of life of the aging population of the world is, to a great extent, determined by the normal aging process of neurons in the central nervous system and especially by the occurrence of diseases characterized by accelerated neuronal loss: diseases which are traditionally designated as being neurodegenerative. They are presently amongst the major contributors to disability and disease in human populations.

Alzheimer's disease is the most prevalent of the neurodegenerative diseases followed by Parkinson's disease. Amyotrophic lateral sclerosis and Huntington's disease affect smaller numbers of patients but have devastating consequences. A large number of other rarer neurodegenerative diseases have similar profound effects on the patients and families who are afflicted by these illnesses. Research into the pathogenesis and treatment for these disorders is exploding exponentially. To a great extent this has been fostered by major advances in genetics, since we now know mutations that are associated with a large number of these illnesses. This includes familial forms of Alzheimer's disease, Parkinson's disease, fronto-temporal dementia, ALS, Huntington's disease and a variety of ataxias.

Type
Chapter
Information
Neurodegenerative Diseases
Neurobiology, Pathogenesis and Therapeutics
, pp. xxi - xxii
Publisher: Cambridge University Press
Print publication year: 2005

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  • Preface
  • M. Flint Beal, Cornell University, New York, Anthony E. Lang, University of Toronto, Albert C. Ludolph, Universität Ulm, Germany
  • Book: Neurodegenerative Diseases
  • Online publication: 04 August 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544873.001
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  • Preface
  • M. Flint Beal, Cornell University, New York, Anthony E. Lang, University of Toronto, Albert C. Ludolph, Universität Ulm, Germany
  • Book: Neurodegenerative Diseases
  • Online publication: 04 August 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544873.001
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Preface
  • M. Flint Beal, Cornell University, New York, Anthony E. Lang, University of Toronto, Albert C. Ludolph, Universität Ulm, Germany
  • Book: Neurodegenerative Diseases
  • Online publication: 04 August 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544873.001
Available formats
×