From Homeostasis to Allodynamic Regulation

doi:10.1017/9781107415782.018

18 - From Homeostasis to Allodynamic Regulation

from Topical Psychophysiology

Published online by Cambridge University Press: 27 January 2017

Gary G. Berntson ,

John T. Cacioppo and

Jos A. Bosch

Edited by

John T. Cacioppo ,

Louis G. Tassinary and

Gary G. Berntson

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John T. Cacioppo: Affiliation:
University of Chicago
Louis G. Tassinary: Affiliation:
Texas A & M University
Gary G. Berntson: Affiliation:
Ohio State University

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Type: Chapter
Information: Handbook of Psychophysiology , pp. 401 - 426

DOI: https://doi.org/10.1017/9781107415782.018 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2016

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References

Adlan, A. M., Lip, G. Y., Paton, J. F., Kitas, G. D., & Fisher, J. P. (2014). Autonomic function and rheumatoid arthritis: a systematic review. Seminars in Arthritis and Rheumatism, 44: 283–304.Google Scholar

Anane, L. H., Edwards, K. M., Burns, V. E., Zanten, J. J., Drayson, M. T., & Bosch, J. A. (2010). Phenotypic characterization of gammadelta T cells mobilized in response to acute psychological stress. Brain, Behavior, and Immunity, 24: 608–614.Google Scholar

Andersson, U. & Tracey, K. J. (2012). Neural reflexes in inflammation and immunity. Journal of Experimental Medicine, 209: 1057–1068.Google Scholar

Aston-Jones, G., Rajkowski, J., Kubiak, P., Valentino, R. J., & Shipley, M. T. (1996). Role of the locus coeruleus in emotional activation, Progress in Brain Research, 107: 379–402.Google Scholar

Backhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I. (2005). Host–bacterial mutualism in the human intestine. Science, 307: 1915–1920.Google Scholar

Banks, W. A. & Farrell, C. L. (2003). Impaired transport of leptin across the blood–brain barrier in obesity is acquired and reversible. American Journal of Physiology: Endocrinology and Metabolism, 285: E10–E15.Google Scholar

Bautista, D. M., Wilson, S. R., & Hoon, M. A. (2014). Why we scratch an itch: the molecules, cells and circuits of itch. Nature Neuroscience, 17: 175–182.Google Scholar

Bernard, C. (1878). Leçons sur les phénomènes de la vie communes aux animaux et aux végétaux. Paris: B. Baillière et Fils. Trans. Hoff, H. E., Guillemin, R., and Guillemin, L. as Lectures on the Phenomena of Life Common to Animals and Plants. Springfield, IL: Charles C. Thomas, 1974.Google Scholar

Berntson, G. G. (2006). Reasoning about brains. In Cacioppo, J. T., Visser, P. S., & Pickett, C. L. (eds.), Social Neuroscience: People Thinking about People (pp. 1–11). Cambridge, MA: MIT Press.Google Scholar

Berntson, G. G., Boysen, S. T., & Cacioppo, J. T. (1993a). Neurobehavioral organization and the cardinal principle of evaluative bivalence. Annals of the New York Academy of Sciences, 702: 75–102.Google Scholar

Berntson, G. G. & Cacioppo, J. T. (2007). Integrative physiology: homeostasis, allostasis, and the orchestration of systemic physiology. In Cacioppo, J. T., Berntson, G. G., & Tassinary, L. G. (eds.), Handbook of Psychophysiology, 3rd edn. (pp. 433–452). Cambridge University Press.Google Scholar

Berntson, G. G. & Cacioppo, J. T. (2013). The functional neuroarchitecture of evaluative processes. In Elliot, A. J. (ed.), Handbook of Approach and Avoidance Motivation (pp. 307–21). New York: Psychology Press.Google Scholar

Berntson, G. G., Cacioppo, J. T., Binkley, P. F., Uchino, B. N., Quigley, K. S., & Fieldstone, A. (1994a). Autonomic cardiac control: III. Psychological stress and cardiac response in autonomic space as revealed by pharmacological blockades. Psychophysiology, 31: 599–608.Google Scholar

Berntson, G. G., Cacioppo, J. T., & Quigley, K. S. (1991). Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint. Psychological Review, 98: 459–487.Google Scholar

Berntson, G. G., Cacioppo, J. T., & Quigley, K. S. (1993b). Cardiac psychophysiology and autonomic space in humans: empirical perspectives and conceptual implications. Psychological Bulletin, 114: 296–322.Google Scholar

Berntson, G. G., Cacioppo, J. T., & Quigley, K. S. (1994b). Autonomic cardiac control: I. Estimation and validation from pharmacological blockades. Psychophysiology 31: 572–585.Google Scholar

Berntson, G. G., Cacioppo, J. T., Quigley, K. S., & Fabro, V. J. (1994c). Autonomic space and psychophysiological response. Psychophysiology, 31: 44–61.Google Scholar

Berntson, G. G., Norman, G. J., Hawkley, L. C., & Cacioppo, J. T. (2008). Cardiac autonomic balance versus cardiac regulatory capacity. Psychophysiology, 45: 643–652.Google Scholar

Berntson, G. G., Sarter, M., & Cacioppo, J. T. (1998). Anxiety and cardiovascular reactivity: the basal forebrain cholinergic link. Behavioural Brain Research, 94: 225–248.Google Scholar

Berntson, G. G., Sarter, M., & Cacioppo, J. T. (2003). Ascending visceral regulation of cortical affective information processing. European Journal of Neuroscience, 18: 2103–2109.Google Scholar

Berthoud, H. R., Bereiter, D. A., Trimble, E. R., Siegel, E. G., & Jeanrenaud, B. (1981). Cephalic phase, reflex insulin secretion. Neuroanatomical and Physiological Characterization. Diabetologia, 20: 393–401.Google Scholar

Blascovich, J., Mendes, W. B., Hunter, S. B., & Salomon, K. (1999). Social “facilitation” as challenge and threat. Journal of Personality and Social Psychology, 77: 68–77.Google Scholar

Bohus, B., Benus, R. F., Fokkema, D. S., Koolhaas, J. M., Nyakas, G. A., van Oortmerssen, G. A., … & Steffens, A. B. (1988). Neuroendocrine states and behavioral and physiological stress responses. In Wiegant, M. & de Wied, D. (eds.), Progress in Brain Research, vol. 72 (pp. 57–70). Amsterdam: Elsevier.Google Scholar

Bosch, J. A. (2014). The use of saliva markers in psychobiology: mechanisms and methods. Monographs in Oral Science, 24: 99–108.Google Scholar

Bosch, J. A., Berntson, G. G., Cacioppo, J. T., Dhabhar, F. S., & Marucha, P. T. (2003a). Acute stress evokes a selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular disease. Brain, Behavior, and Immunity, 17: 251–259.Google Scholar

Bosch, J. A., Berntson, G. G., Cacioppo, J. T., & Marucha, P. T. (2005). Differential mobilization of functionally distinct natural killer subsets during acute psychologic stress. Psychosomatic Medicine, 67: 366–375.Google Scholar

Bosch, J. A., de Geus, E. J., Carroll, D., Goedhart, A. D., Anane, L. A., van Zanten, J. J., … & Edwards, K. M. (2009). A general enhancement of autonomic and cortisol responses during social evaluative threat. Psychosomatic Medicine, 71: 877–885.Google Scholar

Bosch, J. A., de Geus, E. J., Kelder, A., Veerman, E. C., Hoogstraten, J., & Amerongen, A. V. (2001). Differential effects of active versus passive coping on secretory immunity. Psychophysiology, 38: 836–846.Google Scholar

Bosch, J. A., de Geus, E. J., Ligtenberg, T. J., Nazmi, K., Veerman, E. C., Hoogstraten, J., & Amerongen, A. V. (2000). Salivary MUC5B-mediated adherence (ex vivo) of Helicobacter pylori during acute stress. Psychosomatic Medicine, 62: 40–49.Google Scholar

Bosch, J. A., de Geus, E. J., Veerman, E. C., Hoogstraten, J., & Nieuw Amerongen, A. V. (2003b). Innate secretory immunity in response to laboratory stressors that evoke distinct patterns of cardiac autonomic activity. Psychosomatic Medicine, 65: 245–258.Google Scholar

Bosch, J. A., Veerman, E. C., de Geus, E. J., & Proctor, G. B. (2011). Alpha-amylase as a reliable and convenient measure of sympathetic activity: don’t start salivating just yet! Psychoneuroendocrinology, 36: 449–453.Google Scholar

Boychuk, C. R., Gyarmati, P., Xu, H., & Smith, B. N. (2015). Glucose sensing by GABAergic neurons in the mouse nucleus tractus solitarii. Journal of Neurophysiology, 114: 999–1007.Google Scholar

Bradley, M. M., Miccoli, L., Escrig, M. A., & Lang, P. J. (2008). The pupil as a measure of emotional arousal and autonomic activation. Psychophysiology, 45: 602–607.Google Scholar

Bradley, P. B. & Elkes, J. (1953). The effect of atropine, hyoscyamine, physostigmine, and neostigmine on the electrical activity of the brain of the conscious cat. Journal of Physiology, 120: 14–15.Google Scholar

Brody, S., Keller, U., Degen, L., Cox, D. J., & Schächinger, H. (2004). Selective processing of food words during insulin-induced hypoglycemia in healthy humans. Psychopharmacology, 173: 217–220.Google Scholar

Brydon, L. (2011). Adiposity, leptin and stress reactivity in humans. Biological Psychology, 86: 114–120.Google Scholar

Burdakov, D., Luckman, S. M., & Verkhratsky, A. (2005). Glucose-sensing neurons of the hypothalamus. Philosophical Transactions of the Royal Society of London B: Biological Sciences, 360: 2227–2235.Google Scholar

Butler, J. E. (2007). Drive to the human respiratory muscles. Respiratory Physiology & Neurobiology, 159: 115–126.Google Scholar

Cacioppo, J. T. (1994). Social neuroscience: autonomic, neuroendocrine, and immune responses to stress. Psychophysiology, 31: 113–128.Google Scholar

Cacioppo, J. T., Berntson, G. G., Binkley, P. F., Quigley, K. S., Uchino, B. N., & Fieldstone, A. (1994). Autonomic cardiac control: II. Basal response, noninvasive indices, and autonomic space as revealed by autonomic blockades. Psychophysiology, 31: 586–598.Google Scholar

Cacioppo, J. T., Berntson, G. G., & Klein, D. J. (1992). What is an emotion? The role of somatovisceral afference, with special emphasis on somatovisceral “illusions.” Review of Personality and Social Psychology, 14: 63–98.Google Scholar

Cacioppo, J. T., Berntson, G. G., Sheridan, J. F., & McClintock, M. K. (2000). Multi-level integrative analyses of human behavior: the complementing nature of social and biological approaches. Psychological Bulletin, 126: 829–843.Google Scholar

Cacioppo, J. T., Malarkey, W. B., Kiecolt-Glaser, J. K., Uchino, B. N., Sgoutas-Emch, S. A., Sheridan, J. F., Berntson, G. G., & Glaser, R. (1995). Heterogeneity in neuroendocrine and immune responses to brief psychological stressors as a function of autonomic cardiac activation. Psychosomatic Medicine, 57: 154–164.Google Scholar

Cacioppo, J. T. & Sandman, C. A. (1978). Physiological differentiation of sensory and cognitive tasks as a function of warning, processing demands, and reported unpleasantness. Biological Psychology, 6: 181–192.Google Scholar

Cacioppo, J. T. & Tassinary, L. G. (1990). Inferring psychological significance from physiological signals. American Psychologist, 45: 16–28.Google Scholar

Cacioppo, J. T., Tassinary, L. G., Stonebraker, T. B., & Petty, R. E. (1987). Self-report and cardiovascular measures of arousal: fractionation during residual arousal. Biological Psychology, 25: 135–151.Google Scholar

Cannon, W. B. (1914). The interrelations of emotions as suggested by recent physiological researches. American Journal of Psychology, 25: 256–282.Google Scholar

Cannon, W. B. (1928). The mechanism of emotional disturbance of bodily functions. New England Journal of Medicine, 198: 877–884.Google Scholar

Cannon, W. B. (1929a). Bodily Changes in Pain, Hunger, Fear, and Rage. Boston, MA: Charles T. Brandford Company.Google Scholar

Cannon, W. B. (1929b). Organization for physiological homeostasis. Physiological Reviews, 9: 399–431.Google Scholar

Cannon, W. B. (1939). The Wisdom of the Body, 2nd edn. London: Kegan Paul, Trench, Trubner & Co.Google Scholar

Cannon, W. B. (1942). Voodoo death. American Anthropologist, 44: 169–181.Google Scholar

Carroll, D. (2011). A brief commentary on cardiovascular reactivity at a crossroads. Biological Psychology, 86: 149–151.Google Scholar

Carruthers, M. & Taggart, P. (1973). Vagotonicity of violence: biochemical and cardiac responses to violent films and television programmes. British Medical Journal, 3: 384–389.Google Scholar

Chida, Y, & Steptoe, A. (2010). Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence. Hypertension, 55: 1026–1032.Google Scholar

Christian, L. M., Galley, J. D., Hade, E. M., Schoppe-Sullivan, S., Kamp Dush, C., & Bailey, M. T. (2015). Gut microbiome composition is associated with temperament during early childhood. Brain, Behavior, and Immunity, 45: 118–127.Google Scholar

Cofer, C. N. & Appley, M. H. (1964). Motivation: Theory and Research. New York: John Wiley.Google Scholar

Cohen, S. & Herbert, T. B. (1996). Health psychology: psychological factors and physical disease from the perspective of human psychoneuroimmunology. Annual Review of Psychology, 47: 113–142.Google Scholar

Contrada, R. J. (2011). Stress, adaptation, and health. In Contrada, R. J. & Baum, A. (eds.), The Handbook of Stress Science: Biology, Psychology, and Health (pp. 1–9). New York: Springer.Google Scholar

Craig, A. D. (2002). How do you feel? Interoception: the sense of the physiological condition of the body. Nature Reviews Neuroscience, 3: 655–666.Google Scholar

Craig, A. D. (2003). Interoception: the sense of the physiological condition of the body. Current Opinion in Neurobiology, 13: 500–505.Google Scholar

Craig, A. D. (2014). How Do You Feel? An Interoceptive Moment with Your Neurobiological Self. Princeton University Press.Google Scholar

Critchley, H. D. & Harrison, N. A. (2013). Visceral influences on brain and behavior. Neuron, 77: 624–638.Google Scholar

Cryan, J. F. & Dinan, T. G. (2012). Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nature Reviews Neuroscience, 13: 701–712.Google Scholar

Damasio, A. R. (1998). Emotion in the perspective of an integrated nervous system. Brain Research Reviews, 26: 83–86.Google Scholar

Damasio, A. R. (2010). Self Comes to Mind: Contructing the Conscious Brain. New York: Heinemann.Google Scholar

Dantzer, R., O’Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008). From inflammation to sickness and depression: when the immune system subjugates the brain. Nature Reviews Neuroscience, 9: 46–56.Google Scholar

Davis, M., Falls, W. A., Campeau, S., & Kim, M. (1993). Fear-potentiated startle: a neural and pharmacological analysis. Behavioural Brain Research, 58: 175–198.Google Scholar

de Lecea, L., Carter, M. E., & Adamantidis, A. (2012). Shining light on wakefulness and arousal. Biological Psychiatry, 71: 1046–1052.Google Scholar

de Wit, L., Luppino, F., van Straten, A., Penninx, B., Zitman, F., & Cuijpers, P. (2010). Depression and obesity: a meta-analysis of community-based studies. Psychiatry Research, 178: 230–235.Google Scholar

Dhabhar, F. S. (2014). Effects of stress on immune function: the good, the bad, and the beautiful. Immunology Research, 58: 193–210.Google Scholar

Dickerson, S. S. & Kemeny, M. E. (2004). Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130: 355–391.Google Scholar

Dienstbier, R. A. (1989). Arousal and physiological toughness: implications for mental and physical health. Psychological Review, 96: 84–100.Google Scholar

DiGirolamo, D. J., Clemens, T. L., & Kousteni, S. (2012). The skeleton as an endocrine organ. Nature Reviews Rheumatology, 8: 674–683.Google Scholar

Dinan, T. G. & Cryan, J. F. (2012). Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology. Psychoneuroendocrinology, 37: 1369–1378.Google Scholar

Dror, O. E. (2014). The Cannon–Bard thalamic theory of emotions: a brief genealogy and reappraisal. Emotion Review, 6: 13–20.Google Scholar

Duffy, E. (1962). Activation and Behavior. New York: John Wiley.Google Scholar

Dworkin, B. R. (1993). Learning and Physiological Regulation. University of Chicago Press.Google Scholar

Dworkin, B. R. & Dworkin, S. (1999). Heterotopic and homotopic classical conditioning of the baroreflex. Integrative Physiology and Behavioral Scinece, 34: 158–176.Google Scholar

Dworkin, B. R., Elbert, T., Rau, H., Birbaumer, N., Pauli, P., Droste, C., & Brunia, C. H. (1994). Central effects of baroreceptor activation in humans: attenuation of skeletal reflexes and pain perceptions. Proceedings of the National Academy of Sciences of the USA, 91: 6329–6333.Google Scholar

Edwards, K. M., Bosch, J. A., Engeland, C. G., Cacioppo, J. T., & Marucha, P. T. (2010). Elevated macrophage migration inhibitory factor (MIF) is associated with depressive symptoms, blunted cortisol reactivity to acute stress, and lowered morning cortisol. Brain, Behavior, and Immunity, 24: 1202–1208.Google Scholar

Edwards, L., McIntyre, D., Carroll, D., Ring, C., & Martin, U. (2002). The human nociceptive flexion reflex threshold is higher during systole than diastole. Psychophysiology, 39: 678–681.Google Scholar

Engel, G. L. (1977). Emotional stress and sudden death. Psychology Today, 11: 114–118.Google Scholar

Erny, D., Hrabe de Angelis, A. L., Jaitin, D., Wieghofer, P., Staszewski, O., David, E., … & Prinz, M. (2015). Host microbiota constantly control maturation and function of microglia in the CNS. Nature Neuroscience, 18: 965–977.Google Scholar

Farr, O. M., Tsoukas, M. A., & Mantzoros, C. S. (2015). Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders. Metabolism, 64: 114–130.Google Scholar

Feldman, S. M. & Waller, H. J. (1962). Dissociation of electrocortical activation and behavioral arousal. Nature, 196: 1320–1322.Google Scholar

Ferguson, A. V. (2014). Circumventricular organs: integrators of circulating signals controlling hydration, energy balance, and immune function. In De Luca, L. A., Menani, J. V., & Johnson, A. K. (eds.), Neurobiology of Body Fluid Homeostasis: Transduction and Integration (pp. 23–36). Boca Raton, FL: CRC Press.Google Scholar

Field, B. C., Chaudhri, O. B., & Bloom, S. R. (2010). Bowels control brain: gut hormones and obesity. Nature Reviews Endocrinology, 6: 444–453.Google Scholar

Fisher, L. (1990). Stress and cardiovascular physiology in animals. In Brown, M., Koob, G., & Rivier, C. (eds.), Stress: Neurobiology and Neuroendocrinology (pp. 463–474). New York: Marcel Dekker.Google Scholar

Folkow, B. (2000). Perspectives on the integrative functions of the “sympatho-adrenomedullary system.” Autonomic Neuroscience, 83: 101–115.Google Scholar

Frankenhaeuser, M. (1982). Challenge–control interaction as reflected in sympathetic-adrenal and pituitary-adrenal activity: comparison between the sexes. Scandinavian Journal of Psychology, Supp. 1: 158–164.Google Scholar

Friedman, B. H. & Kreibig, S. D. (2010). The biopsychology of emotion: current theoretical, empirical, and methodological perspectives. Biological Psychology, 84: 381–382.Google Scholar

Galley, J. D. & Bailey, M. T. (2014). Impact of stressor exposure on the interplay between commensal microbiota and host inflammation. Gut Microbes, 5: 390–396.Google Scholar

Gerin, W. (2011). Acute stress responses in the psychophysiological laboratory. In Contrada, R. J. & Baum, A. (eds.), The Handbook of Stress Science: Biology, Psychology, and Health (pp. 501–514). New York: Springer.Google Scholar

Gianaros, P. J., Onyewuenyi, I. C., Sheu, L. K., Christie, I. C., & Critchley, H. D. (2012). Brain systems for baroreflex suppression during stress in humans. Human Brain Mapping, 33: 1700–1716.Google Scholar

Goedhart, A. D., Willemsen, G., Houtveen, J. H., Boomsma, D. I., & De Geus, E. J. (2008). Comparing low frequency heart rate variability and preejection period: two sides of a different coin. Psychophysiology, 45: 1086–1090.Google Scholar

Goldstein, D. S. & Kopin, I. J. (2007). Evolution of concepts of stress. Stress, 10: 109–120.Google Scholar

Gray, J. A. & McNaughton, N. (1996). The neuropsychology of anxiety: reprise. Nebraska Symposium on Motivation, 43: 61–134.Google Scholar

Gray, T. S. & Bingaman, E. W. (1996). The amygdala: corticotropin-releasing factor, steroids, and stress. Critical Reviews in Neurobiology, 10: 155–168.Google Scholar

Gregg, M. E., Matyas, T. A., & James, J. E. (2002). A new model of individual differences in hemodynamic profile and blood pressure reactivity. Psychophysiology, 39: 64–72.Google Scholar

Guyton, A. C. (1991). Blood-pressure control: special role of the kidneys and body fluids. Science, 252: 1813–1816.Google Scholar

Haapakoski, R., Mathieu, J., Ebmeier, K. P., Alenius, H., & Kivimaki, M. (2015). Cumulative meta-analysis of interleukins 6 and 1beta, tumour necrosis factor alpha and C-reactive protein in patients with major depressive disorder. Brain, Behavior, and Immunity, 49: 206–215.Google Scholar

Hagenaars, M. A., Oitzl, M., & Roelofs, K. (2014). Updating freeze: aligning animal and human research. Neuroscience & Biobehavioral Reviews, 47: 165–176.Google Scholar

Hanlin, L., Price, J., Zhang, G., Assaf, N., Mitchell, J., & Rohleder, N. (2015). Fasting modulates interleukin-6 and cortisol reactivity to the Trier Social Stress Test. Psychoneuroendocrinology, 61: 69.Google Scholar

Harrison, N. A., Brydon, L., Walker, C., Gray, M. A., Steptoe, A., & Critchley, H. D. (2009). Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity. Biological Psychiatry, 66: 407–414.Google Scholar

Harrison, N. A., Cooper, E., Voon, V., Miles, K., & Critchley, H. D. (2013). Central autonomic network mediates cardiovascular responses to acute inflammation: relevance to increased cardiovascular risk in depression? Brain, Behavior, and Immunity, 31: 189–196.Google Scholar

Harrison, N. A., Gray, M. A., Gianaros, P. J., & Critchley, H. D. (2010). The embodiment of emotional feelings in the brain. Journal of Neuroscience, 30: 12878–12884.Google Scholar

Harshaw, C. (2015). Interoceptive dysfunction: toward an integrated framework for understanding somatic and affective disturbance in depression. Psychological Bulletin, 141: 311–363.Google Scholar

Heany, S. J., van Honk, J., Stein, D. J., & Brooks, S. J. (2016). A quantitative and qualitative review of the effects of testosterone on the function and structure of the human social-emotional brain. Metabolic Brain Disease, 31: 157–167.Google Scholar

Henry, J. P. (1986). Neuroendocrine patterns of emotional response. In Plutchick, R. & Kellerman, H. (eds.), Emotion: Theory, Research and Experiences (pp. 37–60). San Diego, CA: Academic Press.Google Scholar

Hofer, P., Lanzenberger, R., & Kasper, S. (2013). Testosterone in the brain: neuroimaging findings and the potential role for neuropsychopharmacology. European Neuropsychopharmacology, 23: 79–88.Google Scholar

Howren, M. B., Lamkin, D. M., & Suls, J. (2009). Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosomatic Medicine, 71: 171–186.Google Scholar

Inagaki, T. K., Muscatell, K. A., Irwin, M. R., Cole, S. W., & Eisenberger, N. I. (2012). Inflammation selectively enhances amygdala activity to socially threatening images. NeuroImage, 59: 3222–3226.Google Scholar

Iriki, M. & Simon, E. (2012). Differential control of efferent sympathetic activity revisited. Journal of Physiological Science, 62: 275–298.Google Scholar

Iwata, J. & LeDoux, J. E. (1988). Dissociation of associative and nonassociative concomitants of classical fear conditioning in the freely behaving rat. Behavioral Neuroscience, 102: 66–76.Google Scholar

James, W. (1884). What is an emotion? Mind, 9: 188–205.Google Scholar

Joels, M. & Baram, T. Z. (2009). The neuro-symphony of stress. Nature Reviews Neuroscience, 10: 459–466.Google Scholar

Jones, B. E. (2003). Arousal systems. Frontiers in Bioscience, 8: S438–S451.Google Scholar

Karsenty, G. & Ferron, M. (2012). The contribution of bone to whole-organism physiology. Nature, 481: 314–320.Google Scholar

Kataoka, N., Hioki, H., Kaneko, T., & Nakamura, K. (2014). Psychological stress activates a dorsomedial hypothalamus-medullary raphe circuit driving brown adipose tissue thermogenesis and hyperthermia. Cell Metabolism, 20: 346–358.Google Scholar

Kawai, M. & Rosen, C. J. (2010). Minireview: a skeleton in serotonin’s closet? Endocrinology, 151: 4103–4108.Google Scholar

Kirschbaum, C., Gonzalez Bono, E., Rohleder, N., Gessner, C., Pirke, K. M., Salvador, A., & Hellhammer, D. H. (1997). Effects of fasting and glucose load on free cortisol responses to stress and nicotine. Journal of Clinical Endocrinology and Metabolism, 82: 1101–1105.Google Scholar

Knox, D., Sarter, M., & Berntson, G. G. (2004). Visceral afferent bias on cortical processing: role of adrenergic afferents to the basal forebrain cholinergic system. Behavioral Neuroscience, 118: 1455–1459.Google Scholar

Kohler, O., Benros, M. E., Nordentoft, M., Farkouh, M. E., Iyengar, R. L., Mors, O., & Krogh, J. (2014). Effect of anti-inflammatory treatment on depression, depressive symptoms, and adverse effects: a systematic review and meta-analysis of randomized clinical trials. JAMA Psychiatry, 71: 1381–1391.Google Scholar

Koizumi, K. & Kollai, M. (1981). Control of reciprocal and non-reciprocal action of vagal and sympathetic efferents: study of centrally induced reactions, Journal of the Autonomic Nervous System, 3: 483–501.Google Scholar

Koizumi, K. & Kollai, M. (1992). Multiple modes of operation of cardiac autonomic control: development of the ideas from Cannon and Brooks to the present, Journal of the Autonomic Nervous System, 41: 19–30.Google Scholar

Kopin, I. J. (1995). Definitions of stress and sympathetic neuronal responses. Annals of the New York Academy of Sciences, 771: 19–30.Google Scholar

Kreibig, S. D. (2010). Autonomic nervous system activity in emotion: a review. Biological Psychology, 84: 394–421.Google Scholar

Lacey, J. I. (1959). Psychophysiological approaches to the evaluation of psychotherapeutic process and outcome. In Rubinstein, E. A. & Parloff, M. B. (eds.), Research in Psychotherapy (pp. 160–208). Washington: APA.Google Scholar

Lacey, J. I. (1967). Somatic response patterning and stress: some revisions of activation theory. In Appley, M. H. & Trumbull, R. (eds.), Psychological Stress: Issues in Research (pp. 4–44). New York: Appleton-Century-Crofts.Google Scholar

Lacey, J. I., Kagan, J., Lacey, B. C., & Moss, H. A. (1963). The visceral level: situational determinants and behavioral correlates of autonomic response patterns. In Knapp, P. H. (ed.), Expression of Emotions in Man (pp. 161–196). New York: International University Press.Google Scholar

Lacourt, T. E., Houtveen, J. H., Veldhuijzen van Zanten, J. J., Bosch, J. A., Drayson, M. T., & Van Doornen, L. J. (2015). Negative affectivity predicts decreased pain tolerance during low-grade inflammation in healthy women. Brain, Behavior, and Immunity, 44: 32–36.Google Scholar

Ladwig, K. H., Marten-Mittag, B., Lowel, H., Doring, A., & Koenig, W. (2003). Influence of depressive mood on the association of CRP and obesity in 3205 middle aged healthy men. Brain, Behavior, and Immunity, 17: 268–275.Google Scholar

Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1998). Emotion, motivation, and anxiety: brain mechanisms and psychophysiology. Biological Psychiatry, 44: 1248–1263.Google Scholar

Levenson, R. W. (2014). The autonomic nervous system and emotion. Emotion Review, 6: 100–112.Google Scholar

Licht, C. M., Vreeburg, S. A., van Reedt Dortland, A. K., Giltay, E. J., Hoogendijk, W. J., DeRijk, R. H., … & Penninx, B. W. (2010). Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic abnormalities. Journal of Clinical Endocrinology and Metabolism, 95: 2458–2466.Google Scholar

Light, K. C. & Obrist, P. A. (1980). Cardiovascular response to stress: effects of opportunity to avoid, shock experience, and performance feedback. Psychophysiology, 17: 243–252.Google Scholar

Loewy, A. D. (1990). Autonomic control of the eye. In Loewy, A. D. & Spyer, K. M. (eds.), Central Regulation of Autonomic Function (pp. 268–285). Oxford University Press.Google Scholar

Lucini, D., Norbiato, G., Clerici, M., & Pagani, M. (2002). Hemodynamic and autonomic adjustments to real life stress conditions in humans. Hypertension, 39: 184–188.Google Scholar

Luppino, F. S., de Wit, L. M., Bouvy, P. F., Stijnen, T., Cuijpers, P., Penninx, B. W., & Zitman, F. G. (2010). Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Archives of General Psychiatry, 67: 220–229.Google Scholar

Magoun, H. W. (1963). The Waking Brain. Springfield, IL: Charles C. Thomas.Google Scholar

Malliani, A. (2005). Heart rate variability: from bench to bedside. European Journal of Internal Medicine, 16: 12–20.Google Scholar

Mason, J. W. (1975a). A historical view of the stress field: part 1. Journal of Human Stress, 1: 6–12.Google Scholar

Mason, J. W. (1975b). A historical view of the stress field: part 2. Journal of Human Stress, 1: 22–36.Google Scholar

Mayer, E. A., Knight, R., Mazmanian, S. K., Cryan, J. F., & Tillisch, K. (2014). Gut microbes and the brain: paradigm shift in neuroscience. Journal of Neuroscience, 34: 15490–15496.Google Scholar

McCabe, P. M. & Schneiderman, P. (1985). Psychophysiologic reactions to stress. In Schneiderman, N. & Tapp, J. T. (eds.), Behavioral Medicine: The Biopsychosocial Approach (pp. 99–131). London: Lawrence Erlbaum Associates.Google Scholar

McCusker, R. H. & Kelley, K. W. (2013). Immune–neural connections: how the immune system’s response to infectious agents influences behavior. Journal of Experimental Biology, 216: 84–98.Google Scholar

McEwen, B. S. (1998). Protective and damaging effects of stress mediators. New England Journal of Medicine, 338: 171–179.Google Scholar

McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: central role of the brain. Physiological Reviews, 87: 873–904.Google Scholar

McEwen, B. S. & Gianaros, P. J. (2010). Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease. Annals of the New York Academy of Sciences, 1186: 190–222.Google Scholar

McEwen, B. S. & Wingfield, J. C. (2010). What is in a name? Integrating homeostasis, allostasis and stress. Hormones and Behavior, 57: 105–111.Google Scholar

McInnis, C. M., Thoma, M. V., Gianferante, D., Hanlin, L., Chen, X., Breines, J. G., … & Rohleder, N. (2014). Measures of adiposity predict interleukin-6 responses to repeated psychosocial stress. Brain, Behavior, and Immunity, 42: 33–40.Google Scholar

Miller, G. E., Freedland, K. E., Carney, R. M., Stetler, C. A., & Banks, W. A. (2003). Pathways linking depression, adiposity, and inflammatory markers in healthy young adults. Brain, Behavior, and Immunity, 17: 276–285.Google Scholar

Moieni, M., Irwin, M. R., Jevtic, I., Breen, E. C., & Eisenberger, N. I. (2015). Inflammation impairs social cognitive processing: a randomized controlled trial of endotoxin. Brain, Behavior, and Immunity, 48: 132–138.Google Scholar

Nagy, T., van Lien, R., Willemsen, G., Proctor, G., Efting, M., Fulop, M., … & Bosch, J. A. (2015). A fluid response: alpha-amylase reactions to acute laboratory stress are related to sample timing and saliva flow rate. Biological Psychology, 109: 111–119.Google Scholar

Nater, U. M., Ditzen, B., Strahler, J., & Ehlert, U. (2013). Effects of orthostasis on endocrine responses to psychosocial stress. International Journal of Psychophysiology, 90: 341–346.Google Scholar

Neumann, I. D. & Slattery, D. A. (2016). Oxytocin in general anxiety and social fear: a translational approach. Biological Psychiatry, 79: 213–221.Google Scholar

Norman, G. J., Berntson, G. G., & Cacioppo, J. T. (2014). Emotion, somatovisceral afference, and autonomic regulation. Emotion Review, 6: 113–123.Google Scholar

Norman, G. J., Cacioppo, J. T., Morris, J. S., Malarkey, W. B., Berntson, G. G., & DeVries, A. C. (2011a). Oxytocin increases autonomic cardiac control: moderation by loneliness. Biological Psychology, 86(3): 174–180.Google Scholar

Norman, G. J., DeVries, A. C., Cacioppo, J. T., & Berntson, G. G. (2011b). Multilevel analyses of stress. In Contrada, R. J. & Baum, A. (eds.), The Handbook of Stress Science: Biology, Psychology, and Health (pp. 619–634). New York: Springer.Google Scholar

Norman, G. J., Hawkley, L. C., Cole, S. W., Berntson, G. G., & Cacioppo, J. T. (2012). Social neuroscience: the social brain, oxytocin, and health. Social Neuroscience, 7: 18–29.Google Scholar

Obrist, P. A. (1981). Cardiovascular Psychophysiology: A Perspective. New York: Plenum Press.Google Scholar

Ottaviani, C., Shapiro, D., Goldstein, I. B., James, J. E., & Weiss, R. (2006). Hemodynamic profile, compensation deficit, and ambulatory blood pressure. Psychophysiology, 43: 46–56.Google Scholar

Pacak, K. & Palkovits, M. (2001). Stressor specificity of central neuroendocrine responses: implications for stress-related disorders. Endocrine Reviews, 22: 502–548.Google Scholar

Packard, M. G. & Goodman, J. (2012). Emotional arousal and multiple memory systems in the mammalian brain. Frontiers in Behavioral Neuroscience, 6: 14.Google Scholar

Paine, N. J., Bosch, J. A., & Van Zanten, J. J. (2012). Inflammation and vascular responses to acute mental stress: implications for the triggering of myocardial infarction. Current Pharmaceutical Design, 18: 1494–1501.Google Scholar

Paine, N. J., Ring, C., Bosch, J. A., Drayson, M. T., Aldred, S., & Veldhuijzen van Zanten, J. J. (2014). Vaccine-induced inflammation attenuates the vascular responses to mental stress. International Journal of Psychophysiology, 93: 340–348.Google Scholar

Pape, H. C., Jungling, K., Seidenbecher, T., Lesting, J., & Reinscheid, R. K. (2010). Neuropeptide S: a transmitter system in the brain regulating fear and anxiety. Neuropharmacology, 58: 29–34.Google Scholar

Parvizi, J. & Damasio, A. (2001). Consciousness and the brainstem. Cognition, 79: 135–160.Google Scholar

Pedersen, B. K. & Febbraio, M. A. (2012). Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nature Reviews Endocrinology, 8: 457–465.Google Scholar

Pfaff, D. W., Kieffer, B. L., & Swanson, L. W. (2008). Mechanisms for the regulation of state changes in the central nervous system: an introduction. Annals of the New York Academy of Sciences, 1129: 1–7.Google Scholar

Qureshi, I. A. & Mehler, M. F. (2013). Towards a “systems”-level understanding of the nervous system and its disorders. Trends in Neurosciences, 36: 674–684.Google Scholar

Raison, C. L. & Miller, A. H. (2013). Role of inflammation in depression: implications for phenomenology, pathophysiology and treatment. Modern Trends in Pharmacopsychiatry, 28: 33–48.Google Scholar

Ramsay, D. S. & Woods, S. C. (2014). Clarifying the roles of homeostasis and allostasis in physiological regulation. Psychological Review, 121: 225–247.Google Scholar

Reagan, L. P. (2007). Insulin signaling effects on memory and mood. Current Opinion in Pharmacology, 7: 633–637.Google Scholar

Rethorst, C. D., Toups, M. S., Greer, T. L., Nakonezny, P. A., Carmody, T. J., Grannemann, B. D., … & Trivedi, M. H. (2013). Pro-inflammatory cytokines as predictors of antidepressant effects of exercise in major depressive disorder. Molecular Psychiatry, 18: 1119–1124.Google Scholar

Riddell, N. E., Burns, V. E., Wallace, G. R., Edwards, K. M., Drayson, M., Redwine, L. S., … & Bosch, J. A. (2015). Progenitor cells are mobilized by acute psychological stress but not beta-adrenergic receptor agonist infusion. Brain, Behavior, and Immunity, 49: 49–53.Google Scholar

Ring, C., Burns, V. E., & Carroll, D. (2002). Shifting hemodynamics of blood pressure control during prolonged mental stress. Psychophysiology, 39: 585–590.Google Scholar

Robbins, T. W., Granon, S., Muir, J. L., Durantou, F., Harrison, A., & Everitt, B. J. (1998). Neural systems underlying arousal and attention: implications for drug abuse. Annals of the New York Academy of Sciences, 846: 222–237.Google Scholar

Robinson, B. F., Epstein, S. E., Beiser, G. D., & Braunwald, E. (1966). Control of heart rate by the autonomic nervous system. Circulation Research, 14: 400–411.Google Scholar

Rohleder, N., Wolf, J. M., Maldonado, E. F., & Kirschbaum, C. (2006). The psychosocial stress-induced increase in salivary alpha-amylase is independent of saliva flow rate. Psychophysiology, 43: 645–652.Google Scholar

Romanovsky, A. A. (2004). Do fever and anapyrexia exist? Analysis of set point-based definitions. American Journal of Physiology: Regulatory and Integrative Comparative Physiology, 287: R992–R995.Google Scholar

Roosterman, D., Goerge, T., Schneider, S. W., Bunnett, N. W., & Steinhoff, M. (2006). Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiological Reviews, 86: 1309–1379.Google Scholar

Rosen, C. J. (2009). Bone: serotonin, leptin and the central control of bone remodeling. Nature Reviews Rheumatology, 5: 657–658.Google Scholar

Sacco, M., Meschi, M., Regolisti, G., Detrenis, S., Bianchi, L., Bertorelli, M., … & Caiazza, A. (2013). The relationship between blood pressure and pain. Journal of Clinical Hypertension (Greenwich), 15: 600–605.Google Scholar

Santisteban, M. M., Ahmari, N., Carvajal, J. M., Zingler, M. B., Qi, Y., Kim, S., … & Zubcevic, J. (2015). Involvement of bone marrow cells and neuroinflammation in hypertension. Circulation Research, 117: 178–191.Google Scholar

Saper, C. B. (2002). The central autonomic nervous system: conscious visceral perception and autonomic pattern generation. Annual Review of Neuroscience, 25: 433–469.Google Scholar

Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews, 21: 55–89.Google Scholar

Sarter, M., Berntson, G. G., & Cacioppo, J. T. (1996). Brain imaging and cognitive neuroscience: toward strong inference in attributing function to structure. American Psychologist, 51: 13–21.Google Scholar

Sarter, M., Bruno, J. P., & Berntson, G. G. (2003). Reticular activating system. In Nadel, L. (ed.), Encyclopedia of Cognitive Science, vol. 3 (pp. 963–967). London: Nature Publishing Group.Google Scholar

Satpute, A. B., Wager, T. D., Cohen-Adad, J., Bianciardi, M., Choi, J. K., Buhle, J. T., … & Feldman Barrett, L. (2013). Identification of discrete functional subregions of the human periaqueductal gray. Proceedings of the National Academy of Sciences of the USA, 110: 17101–17106.Google Scholar

Schaible, H. G. (2014). Nociceptive neurons detect cytokines in arthritis. Arthritis Research & Therapy, 16: 470.Google Scholar

Schellekens, H., Finger, B. C., Dinan, T. G., & Cryan, J. F. (2012). Ghrelin signalling and obesity: at the interface of stress, mood and food reward. Pharmacology & Therapeutics, 135: 316–326.Google Scholar

Schneiderman, N., Ironson, G., & Siegel, S. D. (2005). Stress and health: psychological, behavioral, and biological determinants. Annual Review of Clinical Psychology, 1: 607–628.Google Scholar

Schneiderman, N. & McCabe, P. M. (1989). Psychophysiologic strategies in laboratory research. In Schneiderman, N., Weiss, S. M., & Kaufman, P. G. (eds.), Handbook of Research Methods in Cardiovascular Behavioral Medicine (pp. 349–364). New York: Plenum Press.Google Scholar

Schommer, N. C., Hellhammer, D. H., & Kirschbaum, C. (2003). Dissociation between reactivity of the hypothalamus–pituitary–adrenal axis and the sympathetic–adrenal–medullary system to repeated psychosocial stress. Psychosomatic Medicine, 65: 450–460.Google Scholar

Schroeder, J. P. & Packard, M. G. (2003). Systemic or intra-amygdala injections of glucose facilitate memory consolidation for extinction of drug-induced conditioned reward. European Journal of Neuroscience, 17: 1482–1488.Google Scholar

Schulkin, J. (ed.) (2004). Allostasis, Homeostasis, and the Costs of Physiological Adaptation. Cambridge University Press.Google Scholar

Schulkin, J. (2011). Social allostasis: anticipatory regulation of the internal milieu. Frontiers in Evolutionary Neuroscience, 2: 111.Google Scholar

Schwabe, L., Joels, M., Roozendaal, B., Wolf, O. T., & Oitzl, M. S. (2012). Stress effects on memory: an update and integration. Neuroscience & Biobehavioral Reviews, 36: 1740–1749.Google Scholar

Selye, H. (1950). Stress and the general adaptation syndrome. British Medical Journal, 1: 1383–1392.Google Scholar

Selye, H. (1956). The Stress of Life. New York: McGraw-Hill.Google Scholar

Selye, H. (1973). Homeostasis and heterostasis. Perspectives in Biology and Medicine, 16: 441–445.Google Scholar

Selye, H. (1975). Confusion and controversy in the stress field. Journal of Human Stress, 1: 37–44.Google Scholar

Selye, H. (1976). Stress in Health and Disease. Boston, MA: Butterworths.Google Scholar

Shelton, R. C. & Miller, A. H. (2011). Inflammation in depression: is adiposity a cause? Dialogues in Clinical Neuroscience, 13: 41–53.Google Scholar

Shih, C. D., Chan, S. H., & Chan, J. Y. (1995). Participation of hypothalamic paraventricular nucleus in locus ceruleus-induced baroreflex suppression in rats. American Journal of Physiology, 269: H46–52.Google Scholar

Slominski, A. T., Zmijewski, M. A., Skobowiat, C., Zbytek, B., Slominski, R. M., & Steketee, J. D. (2012). Sensing the environment: regulation of local and global homeostasis by the skin’s neuroendocrine system. Advances in Anatomy, Embryology, and Cell Biology, 212: v, vii, 1–115.Google Scholar

Sokolov, E. N. (1963). Perception and the Conditioned Reflex. New York: Macmillan.Google Scholar

Spencer, S. J., Emmerzaal, T. L., Kozicz, T., & Andrews, Z. B. (2015). Ghrelin’s role in the hypothalamic–pituitary–adrenal axis stress response: implications for mood disorders. Biological Psychiatry, 78: 19–27.Google Scholar

Steenbergen, L., Sellaro, R., van Hemert, S., Bosch, J. A., & Colzato, L. S. (2015). A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain, Behavior, and Immunity, 48: 258–264.Google Scholar

Steinberg, B. E., Tracey, K. J., & Slutsky, A. S. (2014). Bacteria and the neural code. New England Journal of Medicine, 371: 2131–2133.Google Scholar

Sterling, P. (2004). Principles of allostasis: optimal design, predictive regulation, pathophysiology and rational therapeutics. In Schulkin, J. (ed.), Allostasis, Homeostasis, and the Costs of Physiological Adaptation (pp. 17–64). Cambridge University Press.Google Scholar

Sterling, P. (2012). Allostasis: a model of predictive regulation. Physiology & Behavior, 106(1), 5–15.Google Scholar

Sterling, P. & Eyer, J. (1988). Allostasis: a new paradigm to explain arousal pathology. In Fisher, S. & Reason, J. (eds.), Handbook of Life Stress, Cognition and Health (pp. 629–649). New York: John Wiley.Google Scholar

Stern, R. M. & Sison, C. E. E. (1990). Response patterning. In Cacioppo, J. T. & Tassinary, L. G. (eds.), Principles of Psychophysiology: Physical, Social, and Inferential Elements (pp. 193–216). Cambridge University Press.Google Scholar

Strawbridge, R., Arnone, D., Danese, A., Papadopoulos, A., Herane Vives, A., & Cleare, A. J. (2015). Inflammation and clinical response to treatment in depression: a meta-analysis. European Neuropsychopharmacology, 25: 1532–1543.Google Scholar

Sved, A. F., Cano, G., & Card, J. P. (2001). Neuroanatomical specificity of the circuits controlling sympathetic outflow to different targets. Clinical and Experimental Pharmacology & Physiology, 28: 115–119.Google Scholar

Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A., & Updegraff, J. A. (2000). Biobehavioral responses to stress in females: tend-and-befriend, not fight-or-flight. Psychological Review, 107: 411–429.Google Scholar

Thayer, J. F. & Fischer, J. E. (2009). Heart rate variability, overnight urinary norepinephrine and C-reactive protein: evidence for the cholinergic anti-inflammatory pathway in healthy human adults. Journal of Internal Medicine, 265: 439–447.Google Scholar

Uchino, B. N., Cacioppo, J. T., & Kiecolt-Glaser, J. K. (1996). The relationship between social support and physiological processes: a review with emphasis on underlying mechanisms and implications for health. Psychological Bulletin, 119: 488–531.Google Scholar

Ulrich-Lai, Y. M. & Herman, J. P. (2009). Neural regulation of endocrine and autonomic stress responses. Nature Reviews Neuroscience, 10: 397–409.Google Scholar

Van Roon, A. M., Mulder, L. J., Althaus, M., & Mulder, G. (2004). Introducing a baroreflex model for studying cardiovascular effects of mental workload. Psychophysiology, 41: 961–981.Google Scholar

Van Roon, A. M., Mulder, L. J. M., Veldman, J. B. P., & Mulder, G. (1995). Beat-to-beat blood-pressure measurements applied in studies on mental workload. Homeostasis in Health and Disease, 36: 316–324.Google Scholar

Vingerhoets, A. J. (1985). The role of the parasympathetic division of the autonomic nervous system in stress and the emotions. International Journal of Psychosomatics, 32: 28–34.Google Scholar

Vingerhoets, A. J., Ratliff-Crain, J., Jabaaij, L., Menges, L. J., & Baum, A. (1996). Self-reported stressors, symptom complaints and psychobiological functioning: I. Cardiovascular stress reactivity. Journal of Psychosomatic Research, 40: 177–190.Google Scholar

Vrijkotte, T. G., van den Born, B. J., Hoekstra, C. M., Gademan, M. G., van Eijsden, M., de Rooij, S. R., & Twickler, M. (2015). Cardiac autonomic nervous system activation and metabolic profile in young children: the ABCD study. PLoS One, 10: e0138302.Google Scholar

Watson, D. & Pennebaker, J. W. (1989). Health complaints, stress, and distress: exploring the central role of negative affectivity. Psychological Review, 96: 234–254.Google Scholar

Weiner, H. (1992). Perturbing the Organism: The Biology of Stressful Experience. University of Chicago Press.Google Scholar

Wenger, M. A. (1941). The measurement of individual differences in autonomic balance. Psychosomatic Medicine, 3: 427–434.Google Scholar

Werner, J. (1988). Functional mechanisms of temperature regulation, adaptation and fever: complementary system theoretical and experimental evidence. Pharmacology & Therapeutics, 37: 1–23.Google Scholar

Wheaton, B. & Montazer, S. (2009). Stressors, stress, and distress. In Scheid, T. L. & Brown, T. N. (eds.), A Handbook for the Study of Mental Health: Social Contexts, Theories, and Systems, 2nd edn. (pp. 171–199). Cambridge University Press.Google Scholar

Winsky-Sommerer, R., Boutrel, B., & de Lecea, L. (2005). Stress and arousal: the corticotrophin-releasing factor/hypocretin circuitry. Molecular Neurobiology, 32: 285–294.Google Scholar

Wirtz, P. H., Ehlert, U., Emini, L., & Suter, T. (2008). Higher body mass index (BMI) is associated with reduced glucocorticoid inhibition of inflammatory cytokine production following acute psychosocial stress in men. Psychoneuroendocrinology, 33: 1102–1110.Google Scholar

Zigman, J. M., Bouret, S. G., & Andrews, Z. B. (2016). Obesity impairs the action of the neuroendocrine Ghrelin system. Trends in Endocrinology and Metabolism, 27: 54–63.Google Scholar