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Fertility Preservation Fertility Preservation
Principles and Practice
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Section 1 - Introduction

Published online by Cambridge University Press:  27 March 2021

Edited by
Jacques Donnez  and
S. Samuel Kim
Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Fertility Preservation
Principles and Practice
 , pp. 1 - 34
Publisher: Cambridge University Press
Print publication year: 2021

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References

Bavister, BD. Early history of in vitro fertilization. Reprod, 2002;124:181–196.CrossRefGoogle ScholarPubMed
Clarke, GN. A.R.T. and history. Hum Reprod, 2006;21:1645–1650.CrossRefGoogle ScholarPubMed
Yanagimachi, R, Chang, MC. Fertilization of hamster eggs in vitro. Nature, 1963;200:281–282.CrossRefGoogle ScholarPubMed
Edwards, RG. Maturation in vitro of human ovarian oocytes. Lancet, 1965;2:926.CrossRefGoogle ScholarPubMed
Steptoe, PC. Laparoscopy in Gynaecology. Edinburgh: E & S Livingstone, 1967.Google Scholar
Steptoe, PC. Laparoscopy and ovulation. Lancet, 1968;2:913.CrossRefGoogle ScholarPubMed
Edwards, RG, Bavister, BD, Steptoe, PC. Early stages of fertilization in vitro of human oocytes matured in vitro. Nature, 1969;221:632–635.CrossRefGoogle ScholarPubMed
Bavister, BD, Edwards, RG, Steptoe, PC. Identification of the midpiece and tail of the spermatozoon during fertilization of human eggs in vitro. J Reprod Fert, 1969;20:169–170.CrossRefGoogle ScholarPubMed
Steptoe, PC, Edwards, RG. Laparoscopic recovery of pre-ovulatory oocytes after priming of ovaries with gonadotrophins. Lancet, 1970;1:683–689.CrossRefGoogle Scholar
Steptoe, PC, Edwards, RG. Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet, 1976;1:880–882.CrossRefGoogle ScholarPubMed
Steptoe, PC, Edwards, RG. Birth after the reimplantation of a human embryo. Lancet, 1978;2:366.CrossRefGoogle ScholarPubMed
Trounson, A, Leeton, J, Wood, J et al. Pregnancies in the human by fertilization in vitro and embryo transfer in the controlled ovulatory cycle. Science, 1981;212:681–682.CrossRefGoogle ScholarPubMed
Jones, HW, Jones, GS, Andrews, MC, et al. The program for in vitro fertilization at Norfolk. Fertil Steril, 1982;381:14–21.CrossRefGoogle Scholar
Steptoe, PC, Edwards, RG. Observations on 767 clinical pregnancies and 500 live births after human in-vitro fertilization. Hum Reprod, 1986;1:89–94.CrossRefGoogle Scholar
Trounson, A, Mohr, L. Human pregnancy following cryopreservation thawing and transfer of an eight-cell embryo. Nature, 1983;305:707–709.CrossRefGoogle ScholarPubMed
Trounson, A, Leeton, J, Besanko, M et al. Pregnancy established in an infertile patient following transfer of a donated embryo fertilized in vitro. Br Med J, 1983;286:835–838.CrossRefGoogle Scholar
Utian, WF, Goldfarb, JM, Kiwi, R et al. Preliminary experience with in vitro fertilization-surrogate gestational pregnancy. Fertil Steril, 1989;52:633–638.CrossRefGoogle ScholarPubMed
Lenz, S, Lauritsen, JG. Ultrasonically guided percutaneous aspiration of human follicles under local anaesthesia: a new method of collecting oocytes for in vitro fertilization. Fertil Steril, 1982;38:673–677.CrossRefGoogle ScholarPubMed
Gleicher, N, Friberg, J, Fullan, N et al. Egg retrieval for in vitro fertilisation by sonographically controlled vaginal culdocentesis. Lancet, 1983;2:508–509.CrossRefGoogle ScholarPubMed
Wikland, M, Hamberger, L, Enk, L. Transvesical and transvaginal approaches for aspiration of follicles by use of ultrasound. Ann NY Acad Sci, 1985;442:683–689.CrossRefGoogle ScholarPubMed
Porter, RN, Smith, W, Craft, IL et al. Induction of ovulation for in vitro fertilization using buserelin and gonadotrophins. Lancet, 1984;2:1284–1285.CrossRefGoogle Scholar
Frydman, R, Cornel, C, de Zeigler, D et al. Prevention of premature luteinising hormone and progesterone rise with a GnRH antagonist Nal-Glu in controlled ovarian hyperstimulation. Fertil Steril, 1991;56:921–927.Google ScholarPubMed
Germond, M, Dessole, S, Senn, A et al. Successful in vitro fertilisation and embryo transfer after treatment with recombinant human FSH. Lancet, 1992;339:1170.CrossRefGoogle ScholarPubMed
Devroey, P, Mannaerts, B, Smitz, J et al. First established pregnancy and birth after ovarian stimulation with recombinant follicle stimulating hormone (Org 32489). Hum Reprod, 1993;8:863–865.CrossRefGoogle Scholar
Laws-King, A, Trounsen, A, Sathananthan, H et al. Fertilization of human oocytes by microinjection of a single spermatozoon under the zona pellucida. Fertil Steril, 1987;48:637–642.CrossRefGoogle ScholarPubMed
Palermo, G, Joris, H, Devroey, P, Van Steirteghem, A. Pregnancies after intracytoplasmic sperm injection of single spermatozoon into an oocyte. Lancet, 1992;2:17–18.CrossRefGoogle Scholar
Handyside, AH, Kontogianni, EH, Hardy, K et al. Pregnancies from biopsied human pre-implantation embryos sexed by Y-specific DNA amplification. Nature, 1990;344:768–770.CrossRefGoogle Scholar
Verlinsky, Y, Ginsberg, N, Lifchez, A et al. Analysis of the first polar body: preconception genetic diagnosis. Hum Reprod, 1990;5:826–829.CrossRefGoogle ScholarPubMed
Cha, KY, Yoon, SH, Ko, JJ et al. Pregnancy after in vitro fertilization of human follicular oocytes collected from non-stimulated cycle, their culture in vitro and their transfer according to the donor oocyte program. Fertil Steril, 1989. Abstract O-00: In Proceedings of Annual Meeting of the American Fertility Society.Google Scholar
Silber, SJ, Nagy, Z, Liu, J, Tournaye, H et al. The use of epididymal and testicular spermatozoa for intracytoplasmic sperm injection: the genetic implications for male infertility. Hum Reprod, 1995;10:2031–2043.CrossRefGoogle ScholarPubMed
Reijo, R, Lee, T-Y, Salo, P et al. Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nat Gene, 1995;10:383–393.CrossRefGoogle ScholarPubMed
Picton, HM, Wyns, C, Anderson, RA et al. A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys. Hum Reprod, 2015;30:2463–2475.CrossRefGoogle ScholarPubMed
Gosden, RG. Restoration of fertility in sterilized mice by transferring primordial ovarian follicles. Hum Reprod, 1990;5:499–504.CrossRefGoogle Scholar
Gosden, RG, Baird, DT, Wade, JC et al. Restoration of fertility in oophorectomized sheep by ovarian autographs stored at −196°C. Hum Reprod, 1994;9:597–603.CrossRefGoogle Scholar
Oktay, K, Economos, K, Kan, M et al. Endocrine function and oocyte retrieval after autologous transplantation of ovarian cortical strips to the forearm. J Am Med Ass, 2001;286:1490–1493.CrossRefGoogle ScholarPubMed
Donnez, J, Dolmans, M, Demylle, D et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet, 2004;364:1405–1410.CrossRefGoogle ScholarPubMed
Anderson, RA, Wallace, WHB, Telfer, EE et al. Ovarian tissue cryopreservation for fertility preservation: Clinical and research perspectives. Hum Reprod Open, 2017;1. https://doi.org/10.1093/hropen/hox001Google Scholar
Silber, SJ, Lenahan, KM, Levine, DJ et al. Ovarian transplantation between monozygotic twins discordant for premature ovarian failure. N Engl J Med, 2005;353:58–63.CrossRefGoogle ScholarPubMed
Nyboe, Andersen A, Goossens, V, Bhattacharya, S et al. Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE. Hum Reprod, 2009;24:1267–1287.CrossRefGoogle Scholar
De Geyter, C, Calhaz-Jorge, C, Wyns, C et al. The European IVF monitoring consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod, 2018;1–16. Advance access: https://academic.oup.com/humrep/advance-article-abstract/doi/10.1093/humrep/dey242/50Google Scholar
Code of Practice 9th Edition. Human Fertilisation and Embryology Authority, London 2018 (Draft: For publication October 1, 2018). www.hfea.june-2018-code-of-practice-9th-edition-draftGoogle Scholar
International Federation of Fertility Societies (IFFS). IFFS surveillance 2016. Global Reproductive Health Open, 2016;1:1–143.CrossRefGoogle Scholar
Fauser, BC, Edwards, RG. The early days of IVF [editorial]. Hum Reprod Update, 2005;11:439–459.CrossRefGoogle Scholar
Edwards, RG, Sharpe, DJ. Social values and research in human embryology. Nature, 1971;231:87–91.CrossRefGoogle ScholarPubMed
Steptoe, PC, Edwards, RG. Birth after reimplantation of a human embryo. Lancet, 1978;2:366.CrossRefGoogle ScholarPubMed
Edwards, RG, Steptoe, PC. A Matter of Life. London: Hutchinson, 1980.Google Scholar
Jones, HW Jr. The ethics of in vitro fertilization – 1981. In Edwards RG, Purdy JM (eds.) Human Conception in Vitro. London: Academic Press. 351–357.Google Scholar
Jones, HW, Jones, GS, Andrews, MC et al. The programme for in vitro fertilization at Norfolk. Fertil Steril, 1982;38:14–21.CrossRefGoogle Scholar
Wood, C, Trounson, AO. Historical perspectives of IVF. 2000. In Trounson AO, Gardner DK (eds.) Handbook of in Vitro Fertilization, 2nd edn.Google Scholar
Cohen, J, Trounson, A, Dawson, J et al. The early days of IVF outside the UK. Hum Rep Update, 2005;11:439–459.CrossRefGoogle ScholarPubMed
Edwards, RG. Introduction: the beginnings of human in-vitro fertilization. In Gardner, DK. et al. (eds.) Textbook of Assisted Reproductive Techniques. Informa UK Ltd. 2009, 17–30.Google Scholar
Martinez, F et al. Update on fertility preservation from the Barcelona International Society for Fertility Preservation – ESHRE – ASRM 2015 expert meeting: Indications, results and future perspectives. Hum Reprod, 2017;32(9);1802–1811. https://doi.org/10.1093/humrep/dex2180CrossRefGoogle ScholarPubMed
Brown, L. My Life as the World’s First Test-Tube Baby. Bristol: Bristol Books CIC, 2015.Google Scholar
Kovacs, G, Brinsden, PR, DeCherney, A. In-Vitro Fertilization: The Pioneers’ History. Cambridge: Cambridge University Press, 2018.CrossRefGoogle Scholar
Meirow, D, Nugent, D. The effects of radiotherapy and chemotherapy on female reproduction. Hum Reprod Update, 2001;7(6):535–543.CrossRefGoogle ScholarPubMed
Whitehead, E et al. The effect of combination chemotherapy on ovarian function in women treated for Hodgkin’s disease. Cancer, 1983;52(6):988–993.3.0.CO;2-6>CrossRefGoogle ScholarPubMed
Himelstein-Braw, R, Peters, H, Faber, M. Morphological study of the ovaries of leukaemic children. Br J Cancer, 1978;38(1):82–87.CrossRefGoogle ScholarPubMed
Familiari, G et al. Ultrastructure of human ovarian primordial follicles after combination chemotherapy for Hodgkin’s disease. Hum Reprod, 1993;8(12):2080–2087.CrossRefGoogle ScholarPubMed
Sklar, CA et al. Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst, 2006;98(13):890–896.CrossRefGoogle ScholarPubMed
Chemaitilly, W et al. Acute ovarian failure in the childhood cancer survivor study. J Clin Endocrinol Metab, 2006;91(5):1723–1728.CrossRefGoogle ScholarPubMed
Nielsen, SN et al. A 10-year follow up of reproductive function in women treated for childhood cancer. Reprod Biomed Online, 2013;27(2):192–200.CrossRefGoogle ScholarPubMed
Charpentier, AM et al. Anti-Mullerian hormone screening to assess ovarian reserve among female survivors of childhood cancer. J Cancer Surviv, 2014;8(4):548–554.CrossRefGoogle ScholarPubMed
Thomas-Teinturier, C et al. Ovarian reserve after treatment with alkylating agents during childhood. Hum Reprod, 2015;30(6):1437–1446.CrossRefGoogle ScholarPubMed
Luke, B et al. Assisted reproductive technology use and outcomes among women with a history of cancer. Hum Reprod, 2016;31(1):183–189.CrossRefGoogle ScholarPubMed
Meirow, D et al. Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: clinical importance and proposed accurate investigative tool. Hum Reprod, 1999;14(7):1903–1907.CrossRefGoogle ScholarPubMed
Meirow, D et al. Toxicity of chemotherapy and radiation on female reproduction. Clin Obstet Gynecol, 2010;53(4):727–739.CrossRefGoogle ScholarPubMed
Fan, W. Possible mechanisms of paclitaxel-induced apoptosis. Biochem Pharmacol, 1999;57(11):1215–1221.Google ScholarPubMed
Stumm, S et al. Paclitaxel treatment of breast cancer cell lines modulates Fas/Fas ligand expression and induces apoptosis which can be inhibited through the CD40 receptor. Oncology, 2004;66(2):101–111.CrossRefGoogle ScholarPubMed
Roti Roti, EC et al. Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent. PLoS One, 2012;7(8):e42293.CrossRefGoogle ScholarPubMed
Lopes, F et al. Docetaxel induces moderate ovarian toxicity in mice, primarily affecting granulosa cells of early growing follicles. Mol Hum Reprod, 2014;20(10):948–959.CrossRefGoogle ScholarPubMed
Kalich-Philosoph, L et al. Cyclophosphamide triggers follicle activation and “burnout”; AS101 prevents follicle loss and preserves fertility. Sci Transl Med, 2013;5(185):185ra62.CrossRefGoogle ScholarPubMed
Chen, XY et al. Follicle loss and apoptosis in cyclophosphamide-treated mice: What’s the matter? Int J Mol Sci, 2016;17(6)836.Google ScholarPubMed
Ben-Aharon, I et al. Doxorubicin-induced ovarian toxicity. Reprod Biol Endocrinol, 2010;8:20.CrossRefGoogle ScholarPubMed
Lopez, SG, Luderer, U. Effects of cyclophosphamide and buthionine sulfoximine on ovarian glutathione and apoptosis. Free Radic Biol Med, 2004;36(11):1366–1377.CrossRefGoogle ScholarPubMed
Anderson, RA et al. The effects of chemotherapy and long-term gonadotrophin suppression on the ovarian reserve in premenopausal women with breast cancer. Hum Reprod, 2006;21(10):2583–2592.CrossRefGoogle ScholarPubMed
Rosendahl, M et al. Dynamics and mechanisms of chemotherapy-induced ovarian follicular depletion in women of fertile age. Fertil Steril, 2010 June;94(1):156–66, epub March 31.CrossRefGoogle ScholarPubMed
Kalich-Philosoph, L, Roness, H, Carmely, A et al. Cyclophosphamide triggers follicle activation causing ovarian reserve “burn out”; AS101 prevents follicle loss and preserves fertility. Sci Transl Med, 2013;15(5):185.Google Scholar
Lande, Y et al. Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro. Reprod Biomed Online, 2017;34(1):104–114.CrossRefGoogle ScholarPubMed
Chang, EM et al. Cisplatin induces overactivation of the dormant primordial follicle through PTEN/AKT/FOXO3a pathway which leads to loss of ovarian reserve in mice. PLoS One, 2015;10(12):e0144245.CrossRefGoogle ScholarPubMed
Jang, H et al. Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary. J Pineal Res, 2016;60(3):336–347.CrossRefGoogle ScholarPubMed
Durlinger, AL, Visser, JA, Themmen, AP. Regulation of ovarian function: the role of anti-Mullerian hormone. Reproduction, 2002;124(5):601–609.CrossRefGoogle ScholarPubMed
Adhikari, D, Liu, K. Molecular mechanisms underlying the activation of mammalian primordial follicles. Endocr Rev, 2009;30(5):438–464.CrossRefGoogle ScholarPubMed
Kawamura, K et al. Hippo signaling disruption an Akt stimulation of ovarian follicles for infertility treatment. Proc Natl Acad Sci U S A, 2013;110(43):17474–17479.CrossRefGoogle ScholarPubMed
Li, J et al. Activation of dormant ovarian follicles to generate mature eggs. Proc Natl Acad Sci U S A, 2010;107(22):10280–10284.CrossRefGoogle ScholarPubMed
McLaughlin, M et al. Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but compromises development of growing follicles. Mol Hum Reprod, 2014;20(8):736–744.CrossRefGoogle ScholarPubMed
Durlinger, AL et al. Anti-Mullerian hormone inhibits initiation of primordial follicle growth in the mouse ovary. Endocrinology, 2002;143(3):1076–1084.CrossRefGoogle ScholarPubMed
Durlinger, AL et al. Control of primordial follicle recruitment by anti-Mullerian hormone in the mouse ovary. Endocrinology, 1999;140(12):5789–5796.CrossRefGoogle ScholarPubMed
Marcello, MF et al. Structural and ultrastructural study of the ovary in childhood leukemia after successful treatment. Cancer, 1990;66(10):2099–2104.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
Meirow, D et al. Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury. Hum Reprod, 2007;22(6):1626–1633.CrossRefGoogle ScholarPubMed
Nicosia, SV, Matus-Ridley, M, Meadows, AT. Gonadal effects of cancer therapy in girls. Cancer, 1985;55(10):2364–2372.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Soleimani, R, Heytens, E, Oktay, K. Enhancement of neoangiogenesis and follicle survival by sphingosine-1-phosphate in human ovarian tissue xenotransplants. PLoS One, 2011;6(4):e19475.CrossRefGoogle ScholarPubMed
Ben-Aharon, I et al. Chemotherapy-induced ovarian failure as a prototype for acute vascular toxicity. Oncologist, 2012;17(11):1386–1393.CrossRefGoogle ScholarPubMed
Bar-Joseph, H et al. In vivo bioimaging as a novel strategy to detect doxorubicin-induced damage to gonadal blood vessels. PLoS One, 2011;6(9):e23492.CrossRefGoogle ScholarPubMed
Sanders, JE et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood, 1996;87:3045–3052.CrossRefGoogle ScholarPubMed
Green, DM et al. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. J Clin Oncol, 2009;27(16):2677–2685.CrossRefGoogle ScholarPubMed
Mackie, EJ, Radford, M, Shalet, SM. Gonadal function following chemotherapy for childhood Hodgkin’s disease. Med Pediatr Oncol, 1996;27(2):74–78.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Behringer, K et al. Secondary amenorrhea after Hodgkin’s lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: a report from the German Hodgkin’s Lymphoma Study Group. J Clin Oncol, 2005;23(30):7555–7564.CrossRefGoogle ScholarPubMed
Brusamolino, E et al. Treatment of early-stage Hodgkin’s disease with four cycles of ABVD followed by adjuvant radio-therapy: analysis of efficacy and long-term toxicity. Haematologica, 2000;85(10):1032–1039.Google ScholarPubMed
De Bruin, ML et al. Treatment-related risk factors for premature menopause following Hodgkin lymphoma. Blood, 2008;111(1):101–108.CrossRefGoogle ScholarPubMed
Hodgson, DC et al. Fertility among female Hodgkin lymphoma survivors attempting pregnancy following ABVD chemotherapy. Hematol Oncol, 2006;25:11–15.CrossRefGoogle Scholar
Gershenson, DM. Management of ovarian germ cell tumors. J Clin Oncol, 2007;25(20):2938–2943.CrossRefGoogle ScholarPubMed
Gershenson, DM. Menstrual and reproductive function after treatment with combination chemotherapy for malignant ovarian germ cell tumors. J Clin Oncol, 1988;6(2):270–275.CrossRefGoogle ScholarPubMed
Park, MC et al. Risk of ovarian failure and pregnancy outcome in patients with lupus nephritis treated with intravenous cyclophosphamide pulse therapy. Lupus, 2004; 13(8):569–574.CrossRefGoogle ScholarPubMed
Blumenfeld, Z et al. Prevention of irreversible chemotherapy-induced ovarian damage in young women with lymphoma by a gonadotrophin-releasing hormone agonist in parallel to chemotherapy. Hum Reprod, 1996;11(8):1620–1626.CrossRefGoogle ScholarPubMed
Blumenfeld, Z. How to preserve fertility in young women exposed to chemotherapy? The role of GnRH agonist cotreatment in addition to cryopreservation of embryo, oocytes, or ovaries. Oncologist, 2007;12(9):1044–1054.CrossRefGoogle ScholarPubMed
Elgindy, EA et al. Gonadatrophin suppression to prevent chemotherapy-induced ovarian damage: a randomized controlled trial. Obstet Gynecol, 2013;121(1):78–86.CrossRefGoogle ScholarPubMed
Gerber, B et al. Effect of luteinizing hormone-releasing hormone agonist on ovarian function after modern adjuvant breast cancer chemotherapy: the GBG 37 ZORO study. J Clin Oncol, 2011;29(17):2334–2341.CrossRefGoogle ScholarPubMed
Munster, PN et al. Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer. J Clin Oncol, 2012;30(5):533–538.CrossRefGoogle ScholarPubMed
Sverrisdottir, A et al. Adjuvant goserelin and ovarian preservation in chemotherapy treated patients with early breast cancer: results from a randomized trial. Breast Cancer Res Treat, 2009;117(3):561–567.CrossRefGoogle ScholarPubMed
Del Mastro, L et al. Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial. JAMA, 2011;306(3):269–276.Google ScholarPubMed
Badawy, A et al. Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study. Fertil Steril, 2009;91(3):694–697.CrossRefGoogle ScholarPubMed
Moore, HC et al. Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy. N Engl J Med, 2015;372(10):923–932.CrossRefGoogle ScholarPubMed
Song, G, Gao, H, Yuan, Z. Effect of leuprolide acetate on ovarian function after cyclophosphamide-doxorubicin-based chemotherapy in premenopausal patients with breast cancer: results from a phase II randomized trial. Med Oncol, 2013;30(3):667.CrossRefGoogle ScholarPubMed
Gonfloni, S et al. Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med, 2009;15(10):1179–1185.CrossRefGoogle ScholarPubMed
Kerr, JB et al. DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa. Mol Cell, 2012 November 9;48(3):343–352.CrossRefGoogle ScholarPubMed
Morgan, S et al. Cisplatin and doxorubicin induce distinct mechanisms of ovarian follicle loss; imatinib provides selective protection only against cisplatin. PLoS One, 2013;8(7):e70117.CrossRefGoogle ScholarPubMed
Kim, SY et al. Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death Differ, 2013;20(8):987–997.CrossRefGoogle ScholarPubMed
Hancke, K et al. Sphingosine 1-phosphate protects ovaries from chemotherapy-induced damage in vivo. Fertil Steril, 2007;87(1):172–177.CrossRefGoogle ScholarPubMed
Li, F et al. Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death. Hum Reprod, 2014;29(1):107–113.CrossRefGoogle ScholarPubMed
Zhou, L et al. Rapamycin prevents cyclophosphamide-induced over-activation of primordial follicle pool through PI3K/Akt/mTOR signaling pathway in vivo. J Ovarian Res, 2017;10(1):56.CrossRefGoogle ScholarPubMed
Goldman, KN et al. mTORC1/2 inhibition preserves ovarian function and fertility during genotoxic chemotherapy. Proc Natl Acad Sci U S A, 2017;114(12):3186–3191.CrossRefGoogle ScholarPubMed
Sonigo, C et al. AMH prevents primordial ovarian follicle loss and fertility alteration in cyclophosphamide-treated mice. FASEB J, 2018;33(1):1278–1287,fj201801089R.CrossRefGoogle ScholarPubMed
Kano, M et al. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy. Proc Natl Acad Sci U S A, 2017;114(9):E1688–E1697.CrossRefGoogle ScholarPubMed
Meirow, D, Dor, J. Epidemiology and infertility in cancer patients. In Tulandi, T, Gosden, R (eds.)Preservation of Fertility. Abingdon: Taylor and Francis. 2004, 21–38.Google Scholar
SEER. Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov). SEER*Stat Database: Incidence, Survival & Mortality, November 2017 ed. 2018.Google Scholar
Mertens, AC, Yong, J, Dietz, AC, et al. Conditional survival in pediatric malignancies: analysis of data from the Childhood Cancer Survivor Study and the Surveillance, Epidemiology, and End Results Program. Cancer. 2015;121(7):1108–1117. DOI:10.1002/cncr.29170CrossRefGoogle ScholarPubMed
Landier, W, Armenian, S, Bhatia, S. Late effects of childhood cancer and its treatment. Pediatr Clin North Am, 2015;62(1):275–300. DOI:10.1016/j.pcl.2014.09.017CrossRefGoogle ScholarPubMed
Anderson, RA, Brewster, DH, Wood, R et al. The impact of cancer on subsequent chance of pregnancy: a population-based analysis. Hum Reprod, 2018;33(7):1281–1290. DOI:10.1093/humrep/dey216CrossRefGoogle ScholarPubMed
Wallace, WH, Kelsey, TW, Anderson, RA. Fertility preservation in pre-pubertal girls with cancer: the role of ovarian tissue cryopreservation. Fertil Steril, 2016;105(1):6–12. DOI:10.1016/j.fertnstert.2015.11.041CrossRefGoogle ScholarPubMed
Gerstl, B, Sullivan, E, Chong, S et al. Reproductive outcomes after a childhood and adolescent young adult cancer diagnosis in female cancer survivors: a systematic review and meta-analysis. J Adolesc Young Adult Oncol, 2018. DOI:10.1089/jayao.2018.0036CrossRefGoogle Scholar
Depmann, M, Faddy, MJ, van der Schouw, YT et al. The relationship between variation in size of the primordial follicle pool and age at natural menopause. J Clin Endocrinol Metab, 2015;100(6):E845–E851. DOI:10.1210/jc.2015-1298CrossRefGoogle ScholarPubMed
Kelsey, TW, Anderson, RA, Wright, P, Nelson, SM, Wallace, WH. Data-driven assessment of the human ovarian reserve. Mol Hum Reprod, 2012;18(2):79–87. DOI:10.1093/molehr/gar059CrossRefGoogle ScholarPubMed
Wallace, WH, Kelsey, TW. Human ovarian reserve from conception to the menopause. PLoS One, 2010;5(1):e8772. DOI:10.1371/journal.pone.0008772CrossRefGoogle ScholarPubMed
Johnson, J, Canning, J, Kaneko, T, Pru, JK, Tilly, JL. Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature, 2004;428(6979):145–150. DOI:10.1038/nature02316CrossRefGoogle ScholarPubMed
Lee, HJ, Selesniemi, K, Niikura, Y et al. Bone marrow transplantation generates immature oocytes and rescues long-term fertility in a preclinical mouse model of chemotherapy-induced premature ovarian failure. J Clin Oncol, 2007;25(22):3198–3204. DOI:10.1200/JCO.2006.10.3028CrossRefGoogle Scholar
Johnson, J, Skaznik-Wikiel, M, Lee, HJ et al. Setting the record straight on data supporting postnatal oogenesis in female mammals. Cell Cycle, 2005;4(11):1471–1477. DOI:10.4161/cc.4.11.2186Google ScholarPubMed
Zou, K, Yuan, Z, Yang, Z et al. Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol, 2009;11(5):631–636. DOI:10.1038/ncb1869CrossRefGoogle ScholarPubMed
Hummitzsch, K, Anderson, RA, Wilhelm, D et al. Stem cells, progenitor cells, and lineage decisions in the ovary. Endocr Rev, 2015;36(1):65–91. DOI:10.1210/er.2014-1079CrossRefGoogle ScholarPubMed
McLaughlin, M, Kelsey, TW, Wallace, WH, Anderson, RA, Telfer, EE. Non-growing follicle density is increased following adriamycin, bleomycin, vinblastine and dacarbazine (ABVD) chemotherapy in the adult human ovary. Hum Reprod, 2017;32(1):165–174. DOI:10.1093/humrep/dew260Google ScholarPubMed
Jadoul, P, Dolmans, MM, Donnez, J. Fertility preservation in girls during childhood: is it feasible, efficient and safe and to whom should it be proposed? Hum Reprod Update. 2010;16(6):617–630. DOI:10.1093/humupd/dmq010CrossRefGoogle ScholarPubMed
Gao, W, Liang, JX, Yan, Q. Exposure to radiation therapy is associated with female reproductive health among childhood cancer survivors: a meta-analysis study. J Assist Reprod Genet, 2015;32(8):1179–1186. DOI:10.1007/s10815-015-0490-6CrossRefGoogle ScholarPubMed
Meirow, D, Nugent, D. The effects of radiotherapy and chemotherapy on female reproduction. Hum Reprod Update, 2001;7(6):535–543.CrossRefGoogle ScholarPubMed
Chow, EJ, Stratton, KL, Leisenring, WM et al. Pregnancy after chemotherapy in male and female survivors of childhood cancer treated between 1970 and 1999: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol, 2016;17(5):567–576. DOI:10.1016/S1470-2045(16)00086-3CrossRefGoogle ScholarPubMed
Wallace, WH, Thomson, AB, Kelsey, TW. The radiosensitivity of the human oocyte. Hum Reprod, 2003;18(1):117–121.CrossRefGoogle ScholarPubMed
Salooja, N, Szydlo, RM, Socie, G et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet, 2001;358(9278):271–276.CrossRefGoogle ScholarPubMed
Sanders, JE, Hawley, J, Levy, W et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood, 1996;87(7):3045–3052.CrossRefGoogle ScholarPubMed
Wallace, WH, Shalet, SM, Crowne, EC, Morris-Jones, PH, Gattamaneni, HR. Ovarian failure following abdominal irradiation in childhood: natural history and prognosis. Clin Oncol (R Coll Radiol), 1989;1(2):75–79.CrossRefGoogle ScholarPubMed
Anderson, RA, Mitchell, RT, Kelsey, TW et al. Cancer treatment and gonadal function: experimental and established strategies for fertility preservation in children and young adults. Lancet Diabetes Endocrinol, 2015;3(7):556–567. DOI:10.1016/S2213-8587(15)00039-XCrossRefGoogle ScholarPubMed
Wallace, WH, Thomson, AB, Saran, F, Kelsey, TW. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys, 2005;62(3):738–744. DOI:10.1016/j.ijrobp.2004.11.038CrossRefGoogle ScholarPubMed
Davies, HA, Didcock, E, Didi, M et al. Growth, puberty and obesity after treatment for leukaemia. Acta Paediatr Suppl, 1995;411:45–50; discussion 1.CrossRefGoogle ScholarPubMed
Bath, LE, Anderson, RA, Critchley, HO, Kelnar, CJ, Wallace, WH. Hypothalamic-pituitary-ovarian dysfunction after prepubertal chemotherapy and cranial irradiation for acute leukaemia. Hum Reprod, 2001;16(9):1838–1844.CrossRefGoogle ScholarPubMed
Constine, LS, Woolf, PD, Cann, D et al. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med, 1993;328(2):87–94. DOI:10.1056/NEJM199301143280203CrossRefGoogle ScholarPubMed
Merchant, TE, Rose, SR, Bosley, C et al. Growth hormone secretion after conformal radiation therapy in pediatric patients with localized brain tumors. J Clin Oncol, 2011;29(36):4776–4780. DOI:10.1200/JCO.2011.37.9453CrossRefGoogle ScholarPubMed
Green, DM, Nolan, VG, Kawashima, T et al. Decreased fertility among female childhood cancer survivors who received 22–27 Gy hypothalamic/pituitary irradiation: a report from the Childhood Cancer Survivor Study. Fertil Steril, 2011;95(6):1922–1927, 7 e1. DOI:10.1016/j.fertnstert.2011.02.002CrossRefGoogle ScholarPubMed
Green, DM, Kawashima, T, Stovall, M et al. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. J Clin Oncol, 2009;27(16):2677–2685. DOI:10.1200/JCO.2008.20.1541CrossRefGoogle ScholarPubMed
Marci, R, Mallozzi, M, Di Benedetto, L et al. Radiations and female fertility. Reprod Biol Endocrinol, 2018;16(1):112. DOI:10.1186/s12958-018-0432-0CrossRefGoogle ScholarPubMed
Bath, LE, Critchley, HO, Chambers, SE et al. Ovarian and uterine characteristics after total body irradiation in childhood and adolescence: response to sex steroid replacement. Br J Obstet Gynaecol, 1999;106(12):1265–1272.CrossRefGoogle ScholarPubMed
Larsen, EC, Schmiegelow, K, Rechnitzer, C et al. Radiotherapy at a young age reduces uterine volume of childhood cancer survivors. Acta Obstet Gynecol Scand, 2004;83(1):96–102.CrossRefGoogle Scholar
Wo, JY, Viswanathan, AN. Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients. Int J Radiat Oncol Biol Phys, 2009;73(5):1304–1312. DOI:10.1016/j.ijrobp.2008.12.016CrossRefGoogle ScholarPubMed
Zheng, Y, Lei, Q, Jongejan, A et al. The influence of retinoic acid-induced differentiation on the radiation response of male germline stem cells. DNA Repair (Amst), 2018;70:55–66. DOI:10.1016/j.dnarep.2018.08.027CrossRefGoogle ScholarPubMed
Shalet, SM, Tsatsoulis, A, Whitehead, E, Read, G. Vulnerability of the human Leydig cell to radiation damage is dependent upon age. J Endocrinol, 1989;120(1):161–165.CrossRefGoogle ScholarPubMed
Castillo, LA, Craft, AW, Kernahan, J, Evans, RG, Aynsley-Green, A. Gonadal function after 12-Gy testicular irradiation in childhood acute lymphoblastic leukaemia. Med Pediatr Oncol, 1990;18(3):185–189.CrossRefGoogle ScholarPubMed
Grundy, RG, Leiper, AD, Stanhope, R, Chessells, JM. Survival and endocrine outcome after testicular relapse in acute lymphoblastic leukaemia. Arch Dis Child, 1997;76(3):190–196.CrossRefGoogle ScholarPubMed
Leiper, AD, Stanhope, R, Lau, T et al. The effect of total body irradiation and bone marrow transplantation during childhood and adolescence on growth and endocrine function. Br J Haematol, 1987;67(4):419–426.CrossRefGoogle ScholarPubMed
Choi, M, Hayes, JP, Mehta, MP et al. Using intensity-modulated radiotherapy to spare the kidney in a patient with seminoma and a solitary kidney: a case report. Tumori, 2013;99(2):e38–e42. DOI:10.1700/1283.14205CrossRefGoogle Scholar
Jonska-Gmyrek, J, Peczkowski, P, Michalski, W, et al. Radiotherapy in testicular germ cell tumours – a literature review. Contemp Oncol (Pozn), 2017;21(3):203–208. DOI:10.5114/wo.2017.69592Google ScholarPubMed
Argyle, CE, Harper, JC, Davies, MC. Oocyte cryopreservation: where are we now? Hum Reprod Update, 2016;22:440–449.CrossRefGoogle ScholarPubMed
Devroey, P, Van Steirteghem, A. A review of ten years experience of ICSI. Hum Reprod Update, 2004;10:19–28.CrossRefGoogle ScholarPubMed
Ward, E, DeSantis, C, Robbins, A, Kohler, B, Jemal, A. Childhood and adolescent cancer statistics. CA Cancer J Clin, 2014;64:83–103.CrossRefGoogle ScholarPubMed
Oeffinger, KC, Mertens, AC, Sklar, CA et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med, 2006;355:1572–1582.CrossRefGoogle ScholarPubMed
van Dorp, W, Haupt, R, Anderson, RA et al. Reproductive function and outcomes in female survivors of childhood, adolescent, and young adult cancer: a review. J Clin Oncol, 2018:JCO2017763441.Google Scholar
Peate, M, Meiser, B, Hickey, M, Friedlander, M. The fertility-related concerns, needs and preferences of younger women with breast cancer: a systematic review. Breast Cancer Res Treat, 2009;116:215–223.CrossRefGoogle ScholarPubMed
Shandley, LM, Spencer, JB, Fothergill, A et al. Impact of tamoxifen therapy on fertility in breast cancer survivors. Fertil Steril, 2017;107:243–252 e245.CrossRefGoogle ScholarPubMed
Lambertini, M, Kroman, N, Ameye, L et al. Long-term safety of pregnancy following breast cancer according to estrogen receptor status. J Natl Cancer Inst, 2018;110:426–429.CrossRefGoogle ScholarPubMed
Frobisher, C, Lancashire, ER, Winter, DL, Jenkinson, HC, Hawkins, MM. Long-term population-based marriage rates among adult survivors of childhood cancer in Britain. Int J Cancer, 2007;121:846–855.CrossRefGoogle ScholarPubMed
Koch, SV, Kejs, AM, Engholm, G et al. Marriage and divorce among childhood cancer survivors. J Pediatr Hematol Oncol, 2011;33:500–505.CrossRefGoogle ScholarPubMed
Ganz, PA, Rowland, JH, Desmond, K, Meyerowitz, BE, Wyatt, GE. Life after breast cancer: understanding women’s health-related quality of life and sexual functioning. J Clin Oncol, 1998;16:501–514.CrossRefGoogle ScholarPubMed
Howard-Anderson, J, Ganz, PA, Bower, JE, Stanton, AL. Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: a systematic review. J Natl Cancer Inst, 2012;104:386–405.CrossRefGoogle ScholarPubMed
Himelstein-Braw, R, Peters, H, Faber, M. Influence of irradiation and chemotherapy on the ovaries of children with abdominal tumours. Br J Cancer, 1977;36:269–275.CrossRefGoogle ScholarPubMed
Chapman, RM, Sutcliffe, SB, Malpas, JS. Cytotoxic-induced ovarian failure in women with Hodgkin’s disease. I. Hormone function. JAMA, 1979;242:1877–1881.CrossRefGoogle ScholarPubMed
Morgan, S, Anderson, RA, Gourley, C, Wallace, WH, Spears, N. How do chemotherapeutic agents damage the ovary? Hum Reprod Update, 2012;18:525–535.CrossRefGoogle ScholarPubMed
Kalich-Philosoph, L, Roness, H, Carmely, A et al. Cyclophosphamide triggers follicle activation and “burnout”; AS101 prevents follicle loss and preserves fertility. Sci Transl Med, 2013;5:185ra162.CrossRefGoogle ScholarPubMed
Meirow, D, Dor, J, Kaufman, B et al. Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury. Hum Reprod, 2007;22:1626–1633.CrossRefGoogle ScholarPubMed
Oktem, O, Oktay, K. Quantitative assessment of the impact of chemotherapy on ovarian follicle reserve and stromal function. Cancer, 2007;110:2222–2229.CrossRefGoogle ScholarPubMed
Roti Roti, EC, Leisman, SK, Abbott, DH, Salih, SM. Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent. PLoS One, 2012;7:e42293.CrossRefGoogle ScholarPubMed
Anderson, RA, Remedios, R, Kirkwood, AA et al. Chemotherapy regimen, age and pretreatment ovarian reserve as determinants of ovarian function after response-adapted therapy in patients with Hodgkin lymphoma: a prospective cohort study. Lancet Oncol, 2018 October;19(10):1328–1337.CrossRefGoogle Scholar
Meistrich, ML. Male gonadal toxicity. Pediatr Blood Cancer, 2009;53:261–266.CrossRefGoogle ScholarPubMed
van Alphen, MM, van de Kant, HJ, de Rooij, DG. Repopulation of the seminiferous epithelium of the rhesus monkey after X irradiation. Radiat Res, 1988;113:487–500.CrossRefGoogle ScholarPubMed
Poganitsch-Korhonen, M, Masliukaite, I, Nurmio, M et al. Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents. Leukemia, 2017;31:1460–1463.CrossRefGoogle ScholarPubMed
Stukenborg, JB, Alves-Lopes, JP, Kurek, M et al. Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy. Hum Reprod, 2018;33:1677–1683.CrossRefGoogle ScholarPubMed
Green, DM, Liu, W, Kutteh, WH et al. Cumulative alkylating agent exposure and semen parameters in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study. Lancet Oncol, 2014;15:1215–1223.CrossRefGoogle ScholarPubMed
Loren, AW, Mangu, PB, Beck, LN et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol, 2013;31:2500–2510.CrossRefGoogle ScholarPubMed
Mitchell, RT, Stukenborg, JB, Jahnukainen, K. Male hypogonadism due to cancer treatment. In Winters, SJ, Huhtaniemi, IT (eds.) Male Hypogonadism: Basic, Clinical, and Therapeutic Principles. Springer: Humana Press, 2017.Google Scholar
Marmor, D, Grob-Menendez, F, Duyck, F, Delafontaine, D. Very late return of spermatogenesis after chlorambucil therapy: case reports. Fertil Steril, 1992;58:845–846.CrossRefGoogle ScholarPubMed
Imai, A, Ichigo, S, Matsunami, K, Takagi, H, Kawabata, I. Ovarian function following targeted anti-angiogenic therapy with bevacizumab. Mol Clin Oncol, 2017;6:807–810.CrossRefGoogle ScholarPubMed
Wallace, WH, Thomson, AB, Saran, F, Kelsey, TW. Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys, 2005;62:738–744.CrossRefGoogle ScholarPubMed
Sanders, JE, Hawley, J, Levy, W et al. Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation. Blood, 1996;87:3045–3052.CrossRefGoogle ScholarPubMed
Salooja, N, Szydlo, RM, Socie, G et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet, 2001;358:271–276.CrossRefGoogle ScholarPubMed
Signorello, LB, Cohen, SS, Bosetti, C et al. Female survivors of childhood cancer: preterm birth and low birth weight among their children. J Natl Cancer Inst, 2006;98:1453–1461.CrossRefGoogle ScholarPubMed
Reulen, RC, Bright, CJ, Winter, DL et al. Pregnancy and labor complications in female survivors of childhood cancer: the British childhood cancer survivor study. J Natl Cancer Inst, 2017;109. DOI:10.1093/jnci/djx1056CrossRefGoogle ScholarPubMed
Bath, LE, Critchley, HOD, Chambers, SE et al. Ovarian and uterine characteristics after total body irradiation in childhood and adolescence: response to sex steroid replacement. Brit J Obstet Gynaecol, 1999;106:1265–1272.CrossRefGoogle ScholarPubMed
Kelsey, TW, Ginbey, E, Chowdhury, MM et al. A validated normative model for human uterine volume from birth to age 40 years. PLoS One, 2016;11:e0157375.CrossRefGoogle ScholarPubMed
Bath, LE, Anderson, RA, Critchley, HOD, Kelnar, CJH, Wallace, WHB. Hypothalamic–pituitary-ovarian dysfunction after prepubertal chemotherapy and cranial irradiation for acute leukaemia. Hum Reprod, 2001;16:1838–1844.CrossRefGoogle ScholarPubMed
Ogilvy-Stuart, AL, Shalet, SM. Effect of radiation on the human reproductive system. Environ Health Perspect, 1993;101(Suppl 2):109–116.Google ScholarPubMed
van Dorp, W, Mulder, RL, Kremer, LC et al. Recommendations for premature ovarian insufficiency surveillance for female survivors of childhood, adolescent, and young adult cancer: a report from the international late effects of childhood cancer guideline harmonization group in collaboration with the PanCareSurFup consortium. J Clin Oncol, 2016;34:3440–3450.CrossRefGoogle Scholar
Green, DM, Kawashima, T, Stovall, M et al. Fertility of female survivors of childhood cancer: a report from the childhood cancer survivor study. J Clin Oncol, 2009;27:2677–2685.CrossRefGoogle ScholarPubMed
Green, DM, Sklar, CA, Boice, JD, Jr. et al. Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study. J Clin Oncol, 2009;27:2374–2381.CrossRefGoogle ScholarPubMed
Chow, EJ, Stratton, KL, Leisenring, WM et al. Pregnancy after chemotherapy in male and female survivors of childhood cancer treated between 1970 and 1999: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol, 2016;17:567–576.CrossRefGoogle ScholarPubMed
Barton, SE, Najita, JS, Ginsburg, ES et al. Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol, 2013;14:873–881.CrossRefGoogle ScholarPubMed
Letourneau, JM, Ebbel, EE, Katz, PP et al. Acute ovarian failure underestimates age-specific reproductive impairment for young women undergoing chemotherapy for cancer. Cancer, 2012;118:1933–1939.CrossRefGoogle ScholarPubMed
Bramswig, JH, Riepenhausen, M, Schellong, G. Parenthood in adult female survivors treated for Hodgkin’s lymphoma during childhood and adolescence: a prospective, longitudinal study. Lancet Oncol, 2015;16:667–675.CrossRefGoogle ScholarPubMed
Behringer, K, Breuer, K, Reineke, T et al. Secondary amenorrhea after Hodgkin’s lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: a report from the German Hodgkin’s Lymphoma Study Group. J Clin Oncol, 2005;23:7555–7564.CrossRefGoogle ScholarPubMed
Swerdlow, AJ, Cooke, R, Bates, A et al. Risk of premature menopause after treatment for Hodgkin’s lymphoma. J Natl Cancer Inst, 2014;106(pii):dju207.CrossRefGoogle ScholarPubMed
Petrek, JA, Naughton, MJ, Case, LD et al. Incidence, time course, and determinants of menstrual bleeding after breast cancer treatment: a prospective study. J Clin Oncol, 2006;24:1045–1051.CrossRefGoogle ScholarPubMed
Bath, LE, Wallace, WH, Shaw, MP, Fitzpatrick, C, Anderson, RA. Depletion of ovarian reserve in young women after treatment for cancer in childhood: detection by anti-Mullerian hormone, inhibin B and ovarian ultrasound. Hum Reprod, 2003;18:2368–2374.CrossRefGoogle ScholarPubMed
Jayasinghe, YL, Wallace, WHB, Anderson, RA. Ovarian function, fertility and reproductive lifespan in cancer patients. Expert Rev Endocrinol Metab, 2018;13:125–136.CrossRefGoogle ScholarPubMed
Anderson, RA, Themmen, APN, Al Qahtani, A, Groome, NP, Cameron, DA. The effects of chemotherapy and long-term gonadotrophin suppression on the ovarian reserve in premenopausal women with breast cancer. Human Reprod, 2006;21:2583–2592.CrossRefGoogle ScholarPubMed
Chai, J, Howie, AF, Cameron, DA, Anderson, RA. A highly-sensitive anti-Mullerian hormone assay improves analysis of ovarian function following chemotherapy for early breast cancer. Eur J Cancer, 2014;50:2367–2374.CrossRefGoogle ScholarPubMed
Dezellus, A, Barriere, P, Campone, M et al. Prospective evaluation of serum anti-Mullerian hormone dynamics in 250 women of reproductive age treated with chemotherapy for breast cancer. Eur J Cancer, 2017;79:72–80.CrossRefGoogle ScholarPubMed
Su, HC, Haunschild, C, Chung, K et al. Prechemotherapy antimullerian hormone, age, and body size predict timing of return of ovarian function in young breast cancer patients. Cancer, 2014;120:3691–3698.CrossRefGoogle ScholarPubMed
Anderson, RA, Cameron, DA. Pretreatment serum anti-mullerian hormone predicts long-term ovarian function and bone mass after chemotherapy for early breast cancer. J Clin Endocrinol Metab, 2011;96:1336–1343.CrossRefGoogle ScholarPubMed
Hagen, CP, Vestergaard, S, Juul, A et al. Low concentration of circulating antimullerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study. Fertil Steril, 2012;98:1602–1608 e1602.CrossRefGoogle Scholar
Steiner, AZ, Pritchard, D, Stanczyk, FZ et al. Association between biomarkers of ovarian reserve and infertility among older women of reproductive age. JAMA, 2017;318:1367–1376.CrossRefGoogle ScholarPubMed
Anderson, RA, Brewster, DH, Wood, R et al. The impact of cancer on subsequent chance of pregnancy: a population-based analysis. Hum Reprod, 2018;33:1281–1290.CrossRefGoogle ScholarPubMed
van Beek, RD, Smit, M, van den Heuvel-Eibrink, MM et al. Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin’s lymphoma with chemotherapy during childhood. Hum Reprod, 2007;22:3215–3222.CrossRefGoogle ScholarPubMed
Green, DM, Zhu, L, Zhang, N et al. Lack of specificity of plasma concentrations of inhibin B and follicle-stimulating hormone for identification of azoospermic survivors of childhood cancer: a report from the St Jude lifetime cohort study. J Clin Oncol, 2013;31:1324–1328.CrossRefGoogle ScholarPubMed
Kelsey, TW, McConville, L, Edgar, AB et al. Follicle Stimulating Hormone is an accurate predictor of azoospermia in childhood cancer survivors. PLoS One, 2017;12:e0181377.CrossRefGoogle ScholarPubMed
Wallace, WH, Smith, AG, Kelsey, TW, Edgar, AE, Anderson, RA Fertility preservation for girls and young women with cancer: population-based validation of criteria for ovarian tissue cryopreservation. Lancet Oncol, 2014;15:1129–1136.CrossRefGoogle Scholar
Jones, GL, Hughes, J, Mahmoodi, N et al. Observational study of the development and evaluation of a fertility preservation patient decision aid for teenage and adult women diagnosed with cancer: the Cancer, Fertility and Me research protocol. BMJ Open, 2017;7: e013219.CrossRefGoogle ScholarPubMed
Peate, M, Meiser, B, Cheah, BC et al. Making hard choices easier: a prospective, multicentre study to assess the efficacy of a fertility-related decision aid in young women with early-stage breast cancer. Br J Cancer, 2012;106:1053–1061.CrossRefGoogle ScholarPubMed
Anderson, RA, Mitchell, RT, Kelsey, TW et al. Cancer treatment and gonadal function: experimental and established strategies for fertility preservation in children and young adults. Lancet Diabetes Endocrinol, 2015;3:556–567.CrossRefGoogle ScholarPubMed