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16B - The Freezing of All Embryos Should Be Used for All IVF Cycles

Against

from Section III - The Best Policy

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

The elective freezing of embryos without fresh transfer is increasingly the preferred protocol for IVF, particularly as it leads to equivalent or better implantation and lower rates of complications. However there is little evidence that every woman will benefit from what is a more prolonged chance to conceive. Therefore it cannot be argued that all patients should undergo this treatment pathway.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Roque, M, Valle, M, Sampaio, M, Geber, S. Does freeze-all policy affect IVF outcome in poor ovarian responders? Ultrasound Obstet Gynecol. 2018;52(4):530–4.CrossRefGoogle ScholarPubMed
Healy, DL, Breheny, S, Halliday, J, et al. Prevalence and risk factors for obstetric haemorrhage in 6730 singleton births after assisted reproductive technology in Victoria Australia. Hum Reprod. 2010;25(1):265–74.CrossRefGoogle ScholarPubMed
Chen, Z-J, Shi, Y, Sun, Y, et al. Fresh versus frozen embryos for infertility in the polycystic ovary syndrome. N Engl J Med. 2016;375(6):523–33.CrossRefGoogle ScholarPubMed
Yarali, H, Polat, M, Mumusoglu, S, Yarali, I, Bozdag, G. Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis. J Assist Reprod Genet. 2016;33(10):1287–304.CrossRefGoogle ScholarPubMed
Munné, S, Kaplan, B, Frattarelli, JL, et al. STAR Study Group: Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial. Fertil Steril. 2019 Dec;112(6):1071–9.CrossRefGoogle Scholar

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